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Yvonne M. W. Janssen-Heininger

Yvonne M. W. Janssen-Heininger

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
14014
World Ranking
12432
National Ranking
5321

Overview

Yvonne M. W. Janssen-Heininger is affiliated with the University of Vermont in the United States and has contributed extensively to research in biochemistry, molecular biology, and medicine. Their work spans multiple subfields, including molecular biology, pulmonary and respiratory medicine, physiology, immunology, and biochemistry.

The scientist's research focuses on key topics such as redox biology and oxidative stress, interstitial lung diseases and idiopathic pulmonary fibrosis, neonatal respiratory health research, glutathione transferases and polymorphisms, asthma and respiratory diseases, sulfur compounds in biology, and neutrophil, myeloperoxidase, and oxidative mechanisms.

Recent papers authored or co-authored by Janssen-Heininger include:

  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo, 2022, Nature Metabolism
  • Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?, 2021, Redox Biology
  • Endoplasmic reticulum stress and glutathione therapeutics in chronic lung diseases, 2020, Redox Biology
  • Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease, 2020, The Journal of Immunology
  • Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2, 2021, Redox Biology

Janssen-Heininger frequently publishes in notable scientific venues, such as:

  • Free Radical Biology and Medicine
  • Redox Biology
  • American Journal of Respiratory Cell and Molecular Biology
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaborations form an important part of Janssen-Heininger's scientific contributions. Frequent co-authors include Albert van der Vliet, Reem Aboushousha, Vikas Anathy, Maximilian B. MacPherson, and Cuixia Erickson.

Best Publications

  • Redox-based regulation of signal transduction : Principles, pitfalls, and promises

    Yvonne M.W. Janssen-Heininger;Brooke T. Mossman;Nicholas H. Heintz;Henry J. Forman

  • Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

    Yvonne M.W Janssen-Heininger;Matthew E Poynter;Patrick A Baeuerle

  • Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta.

    Niki L. Reynaert;Albert van der Vliet;Amy S. Guala;Toby McGovern

  • Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB.

    Ramon C. J. Langen;Annemie M. W. J. Schols;Marco C. J. M. Kelders;Emiel F. M. Wouters

  • Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation.

    Niki L. Reynaert;Karina Ckless;Solange H. Korn;Nanda Vos

  • Redox-Sensitive Kinases of the Nuclear Factor-κB Signaling Pathway

    Cristen Pantano;Niki L. Reynaert;Albert Van Der Vliet;Yvonne M. W. Janssen–Heininger

  • Cooperativity between Oxidants and Tumor Necrosis Factor in the Activation of Nuclear Factor (NF)- κ B

    Yvonne M. W. Janssen-Heininger;Ian Macara;Brooke T. Mossman

  • Hydrogen peroxide as a damage signal in tissue injury and inflammation: murderer, mediator, or messenger?

    Albert van der Vliet;Yvonne M.W. Janssen-Heininger

  • A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation.

    Matthew E. Poynter;Charles G. Irvin;Yvonne M. W. Janssen-Heininger

  • NF-κB Activation in Airways Modulates Allergic Inflammation but Not Hyperresponsiveness

    Matthew E. Poynter;Roy Cloots;Tiest van Woerkom;Kelly J. Butnor

  • Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways.

    Ramon C. J. Langen;Annemie M. W. J. Schols;Marco C. J. M. Kelders;Jos L. J. van der Velden

  • Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-β1

    John F. Alcorn;Amy S. Guala;Jos van der Velden;Brian McElhinney

  • Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation

    Ramon C. J. Langen;Annemie M. W. J. Schols;Marco C. J. M. Kelders;Jos L. J. van der Velden

  • Transforming Growth Factor-β1 Suppresses Airway Hyperresponsiveness in Allergic Airway Disease

    John F. Alcorn;Lisa M. Rinaldi;Elizabeth F. Jaffe;Mirjam van Loon

  • Influenza Induces Endoplasmic Reticulum Stress, Caspase-12–Dependent Apoptosis, and c-Jun N-Terminal Kinase–Mediated Transforming Growth Factor–β Release in Lung Epithelial Cells

    Elle C. Roberson;Jane E. Tully;Amy S. Guala;Jessica N. Reiss

  • Apoptosis in lung pathophysiology

    Alan Fine;Yvonne Janssen-Heininger;Rebecca P. Soultanakis;Stephen G. Swisher

  • Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

    Vikas Anathy;Scott W. Aesif;Amy S. Guala;Marije Havermans

  • Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses

    Milena Hristova;Aida Habibovic;Carmen Veith;Yvonne M.W. Janssen-Heininger

  • Oxidative stress in chronic lung disease: From mitochondrial dysfunction to dysregulated redox signaling.

    Albert van der Vliet;Yvonne M.W. Janssen-Heininger;Vikas Anathy

  • Nuclear Factor-κB Activation in Airway Epithelium Induces Inflammation and Hyperresponsiveness

    Cristen Pantano;Jennifer L. Ather;John F. Alcorn;Matthew E. Poynter

Frequent Co-Authors

Albert van der Vliet
Albert van der Vliet University of Vermont
Emiel F.M. Wouters
Emiel F.M. Wouters Maastricht University
Matthew E. Poynter
Matthew E. Poynter University of Vermont
Charles G. Irvin
Charles G. Irvin University of Vermont
John F. Alcorn
John F. Alcorn Children's Hospital of Pittsburgh
Douglas J. Taatjes
Douglas J. Taatjes University of Vermont
Ye-Shih Ho
Ye-Shih Ho Wayne State University
Nicholas H. Heintz
Nicholas H. Heintz University of Vermont
Ralph C. Budd
Ralph C. Budd University of Vermont
Annemie M. W. J. Schols
Annemie M. W. J. Schols Maastricht University

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