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John J. Mieyal

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
10112
World Ranking
17953
National Ranking
7349

John J. Mieyal publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John J. Mieyal sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 103 publications — 6th percentile

6% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John J. Mieyal D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John J. Mieyal sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John J. Mieyal is affiliated with Case Western Reserve University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in several subfields including molecular biology, biochemistry, immunology, and organic chemistry.

The scientist's work covers various main topics, such as:

  • Sulfur Compounds in Biology
  • Redox biology and oxidative stress
  • Glutathione Transferases and Polymorphisms
  • Phagocytosis and Immune Regulation
  • Synthesis and Characterization of Heterocyclic Compounds

John J. Mieyal has published research in different scientific venues, notably in:

  • Antioxidants
  • mBio

Among their recent papers are:

  • "Glutathione and Glutaredoxin-Key Players in Cellular Redox Homeostasis and Signaling," published in 2023 in Antioxidants
  • "Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300," published in 2021 in mBio

Their work has involved collaboration with multiple frequent coauthors including:

  • Yuh-Cherng Chai
  • David A. Davis
  • Haydar Bulut
  • Prabha Shrestha
  • Amulya Yaparla

This body of work contributes to understanding biochemical processes related to cellular redox homeostasis, immune regulation, and molecular mechanisms of enzyme activity modification. Throughout their career, the scientist has focused on detailed molecular interactions and the roles of specific sulfur-containing compounds in biology.

Best Publications

  • Molecular Mechanisms and Clinical Implications of Reversible Protein S-Glutathionylation

    John J. Mieyal;John J. Mieyal;Molly M. Gallogly;Suparna Qanungo;Elizabeth A. Sabens;Elizabeth A. Sabens

  • Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress.

    Molly M Gallogly;John J Mieyal

  • Glutaredoxin: Role in Reversible Protein S-Glutathionylation and Regulation of Redox Signal Transduction and Protein Translocation

    Melissa D. Shelton;P. Boon Chock;John J. Mieyal

  • Reversible Glutathionylation Regulates Actin Polymerization in A431 Cells

    Jun Wang;Emily S. Boja;Wuhong Tan;Ephrem Tekle

  • Dysregulation of glutathione homeostasis in neurodegenerative diseases.

    William M. Johnson;Amy L. Wilson-Delfosse;John. J. Mieyal

  • Thioltransferase is a specific glutathionyl mixed disulfide oxidoreductase.

    Stephen A. Gravina;John J. Mieyal

  • Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis

    Carol A. Chrestensen;David W. Starke;John J. Mieyal

  • Mechanistic and Kinetic Details of Catalysis of Thiol-Disulfide Exchange by Glutaredoxins and Potential Mechanisms of Regulation

    Molly M. Gallogly;David W. Starke;John J. Mieyal;John J. Mieyal

  • Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction.

    David W. Starke;P. Boon Chock;John J. Mieyal

  • Thioltransferase (Glutaredoxin) Is Detected Within HIV-1 and Can Regulate the Activity of Glutathionylated HIV-1 Protease in Vitro

    David A. Davis;Fonda M. Newcomb;David W. Starke;David E. Ott

  • Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity.

    Yanwu Yang;Shu Chuan Jao;Sambasivarao Nanduri;David W. Starke

  • Glutathione Supplementation Potentiates Hypoxic Apoptosis by S-Glutathionylation of p65-NFκB *

    Suparna Qanungo;David W. Starke;Harish V. Pai;John J. Mieyal

  • Reversible Inactivation of α-Ketoglutarate Dehydrogenase in Response to Alterations in the Mitochondrial Glutathione Status†

    Amy C. Nulton-Persson;David W. Starke;John J. Mieyal;Luke I. Szweda

  • Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation

    John J. Mieyal;P. Boon Chock

  • Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin

    Jun Wang;Ephrem Tekle;Hammou Oubrahim;John J. Mieyal

  • Protein-Thiol Oxidation and Cell Death: Regulatory Role of Glutaredoxins

    Erin M.G. Allen;John J. Mieyal

  • Thioltransferase (Glutaredoxin) Reactivates the DNA-binding Activity of Oxidation-inactivated Nuclear Factor I

    Smarajit Bandyopadhyay;David W. Starke;John J. Mieyal;Richard M. Gronostajski;Richard M. Gronostajski

  • pH profiles indicative of rate-limiting nucleophilic displacement in thioltransferase catalysis.

    Usha Srinivasan;Paul A. Mieyal;John J. Mieyal

  • Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases.

    Melissa D. Shelton;John J. Mieyal

  • Kinetic and mechanistic characterization and versatile catalytic properties of mammalian glutaredoxin 2: implications for intracellular roles.

    Molly M. Gallogly;David W. Starke;Amanda K. Leonberg;Susan M. English Ospina

Frequent Co-Authors

Edward J. Lesnefsky
Edward J. Lesnefsky Virginia Commonwealth University
Timothy S. Kern
Timothy S. Kern University of California, Irvine
Xiongwei Zhu
Xiongwei Zhu Case Western Reserve University
Charles L. Hoppel
Charles L. Hoppel Case Western Reserve University
John J. Lemasters
John J. Lemasters Medical University of South Carolina
Vernon E. Anderson
Vernon E. Anderson Case Western Reserve University
Danyelle M. Townsend
Danyelle M. Townsend Medical University of South Carolina
Richard M. Gronostajski
Richard M. Gronostajski University at Buffalo, State University of New York
Marcin Golczak
Marcin Golczak Case Western Reserve University
Vijayalakshmi Ravindranath
Vijayalakshmi Ravindranath Indian Institute of Science

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