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Biology and Biochemistry

D-Index
52
Citations
8865
World Ranking
16770
National Ranking
6921

Overview

Marcin Golczak is affiliated with Case Western Reserve University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions spanning medicine as well.

Their work encompasses several subfields including molecular biology, biochemistry, ophthalmology, biomedical engineering, and public health, environmental, and occupational health. Key topics addressed in their research cover areas such as retinoids in leukemia and cellular processes, antioxidant activity and oxidative stress, retinal development and disorders, retinal diseases and treatments, ocular surface and contact lens, adipose tissue and metabolism, and ultrasound and hyperthermia applications.

Marcin Golczak has published extensively in various scientific journals. Frequent publication venues include:

  • Journal of Biological Chemistry
  • Journal of Lipid Research
  • The FASEB Journal
  • ACS Chemical Biology
  • Journal of Controlled Release

Among recent papers authored or co-authored by Golczak are:

  • "Retinol-binding protein 2 (RBP2): biology and pathobiology" (2020) published in Critical Reviews in Biochemistry and Molecular Biology
  • "The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids" (2020) published in Journal of Biological Chemistry
  • "Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration" (2020) published in Molecular Pharmacology
  • "LRAT coordinates the negative-feedback regulation of intestinal retinoid biosynthesis from β-carotene" (2021) published in Journal of Lipid Research
  • "Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight" (2020) published in Science Advances

Collaborations in research are a notable aspect of Golczak's career. Frequent co-authors include:

  • William S. Blaner
  • Made Airanthi K. Widjaja-Adhi
  • Johannes von Lintig
  • Rossana M. Calderon
  • Srinivasagan Ramkumar

Best Publications

  • Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.

    David Salom;David T. Lodowski;Ronald E. Stenkamp;Isolde Le Trong

  • Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.

    Gabriel H. Travis;Marcin Golczak;Alexander R. Moise;Krzysztof Palczewski

  • Chemistry of the Retinoid (Visual) Cycle

    Philip D. Kiser;Marcin Bernard Golczak;Krzysztof Palczewski

  • A mitochondrial enzyme degrades carotenoids and protects against oxidative stress.

    Jaume Amengual;Glenn P. Lobo;Marcin Bernard Golczak;Hua Nan M Li

  • Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

    Akiko Maeda;Tadao Maeda;Marcin Golczak;Krzysztof Palczewski

  • Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

    Akiko Maeda;Tadao Maeda;Marcin Golczak;Steven Chou

  • Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations

    Sanae Sakami;Tadao Maeda;Grzegorz Bereta;Kiichiro Okano

  • Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration

    Yu Chen;Kiichiro Okano;Tadao Maeda;Vishal Chauhan

  • RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-deficient Animal Model for Matthew-Wood Syndrome

    Andrea Isken;Marcin Bernard Golczak;Vitus Oberhauser;Silke Hunzelmann;Silke Hunzelmann

  • Key enzymes of the retinoid (visual) cycle in vertebrate retina

    Philip D. Kiser;Marcin Bernard Golczak;Akiko Maeda;Krzysztof Palczewski

  • Tetramerization of SAMHD1 Is Required for Biological Activity and Inhibition of HIV Infection

    Junpeng Yan;Sarabpreet Kaur;Maria DeLucia;Caili Hao

  • Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.

    Jaume Amengual;M. Airanthi K. Widjaja-Adhi;Susana Rodriguez-Santiago;Susanne Hessel

  • Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

    Philip D. Kiser;Marcin Bernard Golczak;David Thomas Lodowski;Mark R Chance

  • Human cone photoreceptor dependence on RPE65 isomerase

    Samuel G. Jacobson;Tomas S. Aleman;Artur V. Cideciyan;Elise Heon

  • β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner

    Glenn P. Lobo;Jaume Amengual;Hua Nan M. Li;Marcin Golczak

  • Primary amines protect against retinal degeneration in mouse models of retinopathies

    Akiko Maeda;Marcin Bernard Golczak;Yu Chen;Kiichiro Okano

  • Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.

    Marcin Bernard Golczak;Vladimir Kuksa;Tadao Maeda;Alexander R. Moise

  • The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.

    Johannes Von Lintig;Philip D. Kiser;Marcin Bernard Golczak;Krzysztof Palczewski

  • Stabilizing Function for Myristoyl Group Revealed by the Crystal Structure of a Neuronal Calcium Sensor, Guanylate Cyclase-Activating Protein 1

    Ricardo Stephen;Grzegorz Bereta;Marcin Golczak;Krzysztof Palczewski

  • Mechanism of All-trans-retinal Toxicity with Implications for

    Yu Chen;Kiichiro Okano;Tadao Maeda;Vishal Chauhan

Frequent Co-Authors

Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Akiko Maeda
Akiko Maeda Case Western Reserve University
Johannes von Lintig
Johannes von Lintig Case Western Reserve University
Tadao Maeda
Tadao Maeda Case Western Reserve University
William S. Blaner
William S. Blaner Columbia University
Andreas Engel
Andreas Engel University of Basel
Artur V. Cideciyan
Artur V. Cideciyan University of Pennsylvania
Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
Jacek Skowronski
Jacek Skowronski Case Western Reserve University
Elise Héon
Elise Héon University of Toronto

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