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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
12544
World Ranking
10344
National Ranking
4502

Overview

Johannes von Lintig is affiliated with Case Western Reserve University in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their work spans critical research areas including molecular biology, biochemistry, ophthalmology, nutrition and dietetics, and physiology.

The scientist's publication record includes notable recent papers:

  • Astaxanthin-Shifted Gut Microbiota Is Associated with Inflammation and Metabolic Homeostasis in Mice (2020) published in Journal of Nutrition
  • β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice (2020) published in Journal of Lipid Research
  • Molecular components affecting ocular carotenoid and retinoid homeostasis (2020) published in Progress in Retinal and Eye Research
  • Genomic consequences of domestication of the Siamese fighting fish (2022) published in Science Advances
  • The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids (2020) published in Journal of Biological Chemistry

Johannes von Lintig frequently collaborates with a core group of coauthors, including:

  • Sepalika Bandara
  • Srinivasagan Ramkumar
  • Jean Moon
  • Marcin Golczak
  • Linda D. Thomas

The principal venues where von Lintig's research appears include:

  • Journal of Biological Chemistry
  • Journal of Lipid Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Journal of Nutrition

Von Lintig's research topics focus on antioxidant activity and oxidative stress, retinoids in leukemia and cellular processes, retinal development and disorders, retinal diseases and treatments, mitochondrial function and pathology, aquaculture nutrition and growth, and adipose tissue and metabolism. These topics reflect the broad biochemical and physiological implications of their work, particularly related to carotenoid and retinoid biology.

Best Publications

  • Identification and Characterization of a Mammalian Enzyme Catalyzing the Asymmetric Oxidative Cleavage of Provitamin A

    Cornelia Kiefer;Susanne Hessel;Johanna M. Lampert;Klaus Vogt

  • Transgenic rice (Oryza sativa) endosperm expressing daffodil (Narcissus pseudonarcissus) phytoene synthase accumulates phytoene, a key intermediate of provitamin A biosynthesis

    Peter K. Burkhardt;Peter Beyer;Joachim Wünn;Andreas Klöti

  • Filling the Gap in Vitamin A Research MOLECULAR IDENTIFICATION OF AN ENZYME CLEAVING β-CAROTENE TO RETINAL

    Johannes von Lintig;Klaus Vogt

  • Light‐dependent regulation of carotenoid biosynthesis occurs at the level of phytoene synthase expression and is mediated by phytochrome in Sinapis alba and Arabidopsis thaliana seedlings

    Johannes Von Lintig;Ralf Welsch;Michael Bonk;Giovanni Giuliano

  • Induced β-Carotene Synthesis Driven by Triacylglycerol Deposition in the Unicellular Alga Dunaliella bardawil

    Said Rabbani;Peter Beyer;Johannes v. Lintig;Philippe Hugueney

  • A mitochondrial enzyme degrades carotenoids and protects against oxidative stress.

    Jaume Amengual;Glenn P. Lobo;Marcin Bernard Golczak;Hua Nan M Li

  • Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism.

    Johannes von Lintig

  • CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice

    Susanne Hessel;Anne Eichinger;Andrea Isken;Jaume Amengual

  • A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila

    Cornelia Kiefer;Emerich Sumser;Mathias F. Wernet;Johannes von Lintig

  • Carotenoid oxygenases: cleave it or leave it.

    Giovanni Giuliano;Salim Al-Babili;Johannes von Lintig

  • Regulation and activation of phytoene synthase, a key enzyme in carotenoid biosynthesis, during photomorphogenesis

    Ralf Welsch;Peter Beyer;Philippe Hugueney;Hans Kleinig

  • ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β,β-carotene absorption and vitamin A production

    Glenn P. Lobo;Susanne Hessel;Anne Eichinger;Noa Noy

  • RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-deficient Animal Model for Matthew-Wood Syndrome

    Andrea Isken;Marcin Bernard Golczak;Vitus Oberhauser;Silke Hunzelmann;Silke Hunzelmann

  • Beta-Carotene Reduces Body Adiposity of Mice via BCMO1

    Jaume Amengual;Jaume Amengual;Erwan Gouranton;Yvonne G. J. van Helden;Susanne Hessel

  • Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.

    Jaume Amengual;M. Airanthi K. Widjaja-Adhi;Susana Rodriguez-Santiago;Susanne Hessel

  • Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis.

    Johanna M. Lampert;Jochen Holzschuh;Susanne Hessel;Wolfgang Driever

  • Phytoene synthase from Narcissus pseudonarcissus: functional expression, galactolipid requirement, topological distribution in chromoplasts and induction during flowering

    Michael Schledz;Salim Al-Babili;Johannes Von Lintig;Heinz Haubruck

  • Provitamin A metabolism and functions in mammalian biology

    Johannes von Lintig

  • β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner

    Glenn P. Lobo;Jaume Amengual;Hua Nan M. Li;Marcin Golczak

  • Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids.

    Alexander R. Moise;Johannes von Lintig;Krzysztof Palczewski

Frequent Co-Authors

Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Marcin Golczak
Marcin Golczak Case Western Reserve University
Peter Beyer
Peter Beyer University of Freiburg
Timothy S. Kern
Timothy S. Kern University of California, Irvine
Xiang-Dong Wang
Xiang-Dong Wang Tufts University
Jaap Keijer
Jaap Keijer Wageningen University & Research
Christian Grimm
Christian Grimm University of Zurich
Salim Al-Babili
Salim Al-Babili King Abdullah University of Science and Technology
Tadao Maeda
Tadao Maeda Case Western Reserve University
Andreas Wenzel
Andreas Wenzel Novartis (Switzerland)

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