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Biology and Biochemistry

D-Index
71
Citations
16644
World Ranking
6711
National Ranking
174

Overview

Jaap Keijer is affiliated with Wageningen University & Research in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Physiology, Molecular Biology, Epidemiology, Endocrinology, Diabetes and Metabolism, and Cell Biology.

The main topics explored in their scientific work include:

  • Adipose Tissue and Metabolism
  • Mitochondrial Function and Pathology
  • Diet and Metabolism Studies
  • Nutrition and Health in Aging
  • Diet, Metabolism, and Disease
  • Muscle Physiology and Disorders
  • Muscle Metabolism and Nutrition

Keijer has published multiple papers, with notable recent contributions including:

  • "The Molecular and Physiological Effects of Protein-Derived Polyamines in the Intestine" (2020) in Nutrients
  • Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention (2021) in Brain
  • "Sex differences in skeletal muscle-aging trajectory: same processes, but with a different ranking" (2023) in GeroScience
  • "Role of Oxidative DNA Damage and Repair in Atrial Fibrillation and Ischemic Heart Disease" (2021) in International Journal of Molecular Sciences
  • "Influence of the metabolic state during lactation on milk production in modern sows" (2020) in animal

Frequent co-authors collaborating with Keijer include:

  • Vincent C. J. de Boer
  • Arie G. Nieuwenhuizen
  • Evert M. van Schothorst
  • Robert Kleemann
  • Martien P. M. Caspers

The scientist has published extensively in several key venues, with multiple publications in:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nutrients
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • American Journal of Physiology-Endocrinology and Metabolism

Best Publications

  • Diet-Independent Correlations between Bacteria and Dysfunction of Gut, Adipose Tissue, and Liver: A Comprehensive Microbiota Analysis in Feces and Mucosa of the Ileum and Colon in Obese Mice with NAFLD.

    Eveline Gart;Everton Souto Lima;Frank Schuren;Christa G. F. De Ruiter

  • Tissue Distribution of Quercetin in Rats and Pigs

    Vincent C. J. de Boer;Ashwin A. Dihal;Hester van der Woude;Ilja C. W. Arts

  • Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.

    P. Flachs;O. Horakova;P. Brauner;M. Rossmeisl

  • The secretory function of adipocytes in the physiology of white adipose tissue

    Ping Wang;Edwin Mariman;Johan Renes;Jaap Keijer

  • The application of DNA microarrays in gene expression analysis

    N.L.W. van Hal;O. Vorst;A.M.M.L. van Houwelingen;E.J. Kok

  • Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations

    Aurélia De Pauw;Silvia Tejerina;Martine Raes;Jaap Keijer

  • Concepts for further sustainable production of foods

    A.J. van der Goot;P.J.M. Pelgrom;J.A.M. Berghout;M.E.J. Geerts

  • Rapid yeast estrogen bioassays stably expressing human estrogen receptors α and β, and green fluorescent protein: a comparison of different compounds with both receptor types

    Toine F.H. Bovee;Richard J.R. Helsdingen;Ivonne M.C.M. Rietjens;Jaap Keijer

  • Functional relationship between obesity and male reproduction: from humans to animal models

    K.J. Teerds;D.G. de Rooij;J. Keijer

  • Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine

    Susanne Keipert;Mario Ost;Kornelia Johann;Francine Imber

  • Alteration of serpin specificity by a protein cofactor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties.

    H J Ehrlich;R K Gebbink;J Keijer;M Linders

  • Host‐related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans

    Torsten Bohn;Charles Desmarchelier;Lars O. Dragsted;Charlotte S. Nielsen

  • Biomarkers of Nutrition and Health: New Tools for New Approaches

    Catalina Picó;Francisca Serra;Ana María Rodríguez;Jaap Keijer

  • Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines.

    P. Wang;E.C.M. Mariman;J. Keijer;F.G. Bouwman

  • Challenging homeostasis to define biomarkers for nutrition related health

    Ben van Ommen;Jaap Keijer;Sandra G. Heil;Jim Kaput

  • Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

    John R. Speakman;John R. Speakman;Jaap Keijer

  • SIRT1 stimulation by polyphenols is affected by their stability and metabolism.

    Vincent C.J. de Boer;Marcus C. de Goffau;Ilja C.W. Arts;Peter C.H. Hollman

  • Beta-Carotene Reduces Body Adiposity of Mice via BCMO1

    Jaume Amengual;Jaume Amengual;Erwan Gouranton;Yvonne G. J. van Helden;Susanne Hessel

  • Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils.

    A. J. Verhoeven;B. G. J. M. Bolscher;L. J. Meerhof;R. Van Zwieten

  • Structure of the human plasminogen activator inhibitor 1 gene: nonrandom distribution of introns.

    D J Loskutoff;M Linders;J Keijer;H Veerman

Frequent Co-Authors

Andreu Palou
Andreu Palou University of the Balearic Islands
Peter C. H. Hollman
Peter C. H. Hollman Wageningen University & Research
Ivonne M.C.M. Rietjens
Ivonne M.C.M. Rietjens Wageningen University & Research
Hans Pannekoek
Hans Pannekoek University of Amsterdam
Harry J. Wichers
Harry J. Wichers Wageningen University & Research
Robert Kleemann
Robert Kleemann Netherlands Organisation for Applied Scientific Research
John E. Hesketh
John E. Hesketh Newcastle University
Nicoline M. Soede
Nicoline M. Soede Wageningen University & Research
Edwin C. M. Mariman
Edwin C. M. Mariman Maastricht University
Bas Kemp
Bas Kemp Wageningen University & Research

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