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Angel R. de Lera

Angel R. de Lera

D-Index & Metrics

Chemistry

D-Index
61
Citations
12675
World Ranking
9282
National Ranking
307

Overview

Angel R. de Lera is affiliated with Universidade de Vigo in Spain. Their research spans across the fields of Biochemistry, Genetics and Molecular Biology as well as Chemistry, with a focus on Organic Chemistry, Molecular Biology, Pharmacology, Materials Chemistry, and Plant Science.

The main topics addressed in their work include:

  • Synthetic Organic Chemistry Methods
  • Retinoids in leukemia and cellular processes
  • Antioxidant Activity and Oxidative Stress
  • Microbial Natural Products and Biosynthesis
  • Plant Parasitism and Resistance
  • Histone Deacetylase Inhibitors Research
  • Chemical synthesis and alkaloids

Angel R. de Lera has contributed to several publications, including the following recent papers:

  • Two-hit wonders: The expanding universe of multitargeting epigenetic agents, 2020, Current Opinion in Chemical Biology
  • From carotenoid intake to carotenoid blood and tissue concentrations - implications for dietary intake recommendations, 2020, Nutrition Reviews
  • An alternative, zeaxanthin epoxidase-independent abscisic acid biosynthetic pathway in plants, 2021, Molecular Plant
  • Efficient Mimics for Elucidating Zaxinone Biology and Promoting Agricultural Applications, 2020, Molecular Plant
  • Natural polyenic macrolactams and polycyclic derivatives generated by transannular pericyclic reactions: optimized biogenesis challenging chemical synthesis, 2020, Natural Product Reports

Their frequent co-authors include:

  • Rosana Álvarez
  • Claudio Martínez
  • Ralph Rühl
  • Patricia García-Domínguez
  • Belén Vaz

Angel R. de Lera publishes regularly in the following venues:

  • The Cambridge Structural Database
  • The Journal of Organic Chemistry
  • Natural Product Reports
  • Chemistry - A European Journal
  • Organic Letters

Best Publications

  • Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells.

    Angela Nebbioso;Nicole Clarke;Emilie Voltz;Emmanuelle Germain

  • International Union of Pharmacology. LXIII. Retinoid X Receptors

    Pierre Germain;Pierre Chambon;Gregor Eichele;Ronald M. Evans

  • International Union of Pharmacology. LX. Retinoic Acid Receptors

    Pierre Germain;Pierre Germain;Pierre Chambon;Gregor Eichele;Ronald M. Evans

  • Design of selective nuclear receptor modulators: RAR and RXR as a case study

    Angel R de Lera;William Bourguet;William Bourguet;Lucia Altucci;Hinrich Gronemeyer

  • Palladium-catalyzed intermolecular C(sp3)-H amidation.

    Álvaro Iglesias;Rosana Álvarez;Ángel R. de Lera;Kilian Muñiz

  • Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

    Rosana Álvarez;Belén Vaz;Hinrich Gronemeyer;Ángel R. de Lera

  • Rapid, nongenomic actions of retinoic acid on phosphatidylinositol-3-kinase signaling pathway mediated by the retinoic acid receptor.

    Susana Masiá;Susana Alvarez;Angel R de Lera;Domingo Barettino

  • C-C reductive elimination in palladium complexes, and the role of coupling additives. A DFT study supported by experiment.

    Martín Pérez-Rodríguez;Ataualpa A. C. Braga;Max Garcia-Melchor;Mónica H. Pérez-Temprano

  • Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10

    Oriol Gallego;F. Xavier Ruiz;Albert Ardèvol;Marta Domínguez

  • Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.

    Vivian Pogenberg;Jean-François Guichou;Valérie Vivat-Hannah;Sabrina Kammerer

  • A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor

    Albane le Maire;Catherine Teyssier;Catherine Teyssier;Cathie Erb;Marina Grimaldi

  • Mechanism of the Gold(I)-Catalyzed Rautenstrauch Rearrangement: A Center-to-Helix-to-Center Chirality Transfer

    Olalla Nieto Faza;Carlos Silva Lopez;Rosana Alvarez;Angel R. De Lera

  • Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function

    Virginie Nahoum;Efrén Pérez;Pierre Germain;Fátima Rodríguez-Barrios

  • Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities

    Paola Bontempo;Luigi Mita;Marco Miceli;Antonella Doto

  • 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.

    Ralph Rühl;Agnieszka Krzyżosiak;Anna Niewiadomska-Cimicka;Natacha Rochel

  • Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins.

    J. K. McBee;V. Kuksa;R. Alvarez;A. R. De Lera

  • Theoretical study of the electrocyclic ring closure of hydroxypentadienyl cations.

    Olalla Nieto Faza;Carlos Silva López;Rosana Álvarez;Ángel R. de Lera

  • Bond Ellipticity as a Measure of Electron Delocalization in Structure and Reactivity

    Carlos Silva Lopez;Angel R. de Lera

  • On the Aromatic Character of Electrocyclic and Pseudopericyclic Reactions: Thermal Cyclization of (2Z)-Hexa-2,4-5-trienals and Their Schiff Bases.

    Angel R. de Lera;Rosana Alvarez;Begoña Lecea;Alicia Torrado

  • An alternative, zeaxanthin epoxidase-independent abscisic acid biosynthetic pathway in plants.

    Kun-Peng Jia;Kun-Peng Jia;Jianing Mi;Shawkat Ali;Hajime Ohyanagi

  • Rational design of RAR-selective ligands revealed by RARβ crystal stucture

    Pierre Germain;Sabrina Kammerer;Efrén Pérez;Carole Peluso-Iltis

  • The suzuki reaction in stereocontrolled polyene synthesis: Retinol (vitamin A), its 9- and/or 13-demethyl analogs, and related 9-demethyl-dihydroretinoids

    Alicia Torrado;Beatriz Iglesias;Susana López;Angel R. de Lera

Frequent Co-Authors

Hinrich Gronemeyer
Hinrich Gronemeyer Institute of Genetics and Molecular and Cellular Biology
Lucia Altucci
Lucia Altucci University of Campania "Luigi Vanvitelli"
William Bourguet
William Bourguet University of Montpellier
Luis Castedo
Luis Castedo University of Santiago de Compostela
William H. Okamura
William H. Okamura University of California, Riverside
Vincent Laudet
Vincent Laudet Okinawa Institute of Science and Technology
Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Darrin M. York
Darrin M. York Rutgers, The State University of New Jersey
Catherine A. Royer
Catherine A. Royer Rensselaer Polytechnic Institute
Ramon A. Alvarez-Puebla
Ramon A. Alvarez-Puebla Rovira i Virgili University

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