What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Enzyme
- Gene
The scientist’s investigation covers issues in Biochemistry, Retinoid X receptor, Stereochemistry, Retinoic acid and Nuclear receptor.
His Biochemistry research focuses on Cell biology and how it relates to Rational design.
He has included themes like Retinoid X receptor alpha, Retinoic acid receptor alpha, Retinoid X receptor beta, Receptor and Retinoid X receptor gamma in his Retinoid X receptor study.
Angel R. de Lera interconnects Cancer research, Signal transduction and Endocrinology in the investigation of issues within Receptor.
His Stereochemistry research incorporates elements of Tryptophan, Amino acid, Ring and Suzuki reaction.
In his study, which falls under the umbrella issue of Retinoic acid, Aldose reductase, Tolrestat and Aldehyde Reductase is strongly linked to Aldo-keto reductase.
His most cited work include:
- Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells. (525 citations)
- RAR and RXR modulation in cancer and metabolic disease (403 citations)
- International Union of Pharmacology. LXIII. Retinoid X Receptors (391 citations)
What are the main themes of his work throughout his whole career to date?
Angel R. de Lera mainly investigates Stereochemistry, Biochemistry, Retinoid X receptor, Retinoic acid and Organic chemistry.
The various areas that Angel R. de Lera examines in his Stereochemistry study include Chemical synthesis, Ring, Stille reaction and Stereoselectivity.
His work deals with themes such as Computational chemistry, Bicyclic molecule, Medicinal chemistry and Torquoselectivity, which intersect with Ring.
As part of his studies on Biochemistry, Angel R. de Lera often connects relevant areas like Cell biology.
His Retinoid X receptor research incorporates themes from Receptor and Retinoid, Retinoid X receptor alpha, Retinoid X receptor beta.
His work in Retinoic acid receptor and Tretinoin are all subfields of Retinoic acid research.
He most often published in these fields:
- Stereochemistry (46.10%)
- Biochemistry (15.26%)
- Retinoid X receptor (14.94%)
What were the highlights of his more recent work (between 2015-2021)?
- Stereochemistry (46.10%)
- Retinoid X receptor (14.94%)
- Retinoic acid (12.01%)
In recent papers he was focusing on the following fields of study:
Angel R. de Lera mostly deals with Stereochemistry, Retinoid X receptor, Retinoic acid, Biochemistry and Receptor.
His study connects Stereoselectivity and Stereochemistry.
The Retinoid X receptor study combines topics in areas such as Ligand and Ligand.
Angel R. de Lera is studying Retinoic acid receptor, which is a component of Retinoic acid.
His study explores the link between Biochemistry and topics such as Cell culture that cross with problems in Activator, Metabolite, In vitro and Tumor progression.
His studies in Receptor integrate themes in fields like Nuclear receptor, Retinoid and Tretinoin.
Between 2015 and 2021, his most popular works were:
- Epigenetic polypharmacology: from combination therapy to multitargeted drugs (65 citations)
- An Endogenous Mammalian Retinoid X Receptor Ligand, At Last! (33 citations)
- Alternative retinoid X receptor (RXR) ligands. (27 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- Gene
Angel R. de Lera spends much of his time researching Retinoid X receptor, Receptor, Tretinoin, Epigenetics and Endogeny.
Within the field of Biochemistry and Nuclear receptor Angel R. de Lera studies Retinoid X receptor.
His Nuclear receptor study combines topics in areas such as Calcitriol receptor, Retinoid and Function, Cell biology.
His research on Tretinoin also deals with topics like
- Cancer research and Agonist most often made with reference to Endocrinology,
- Retinoic acid receptor most often made with reference to Internal medicine.
As part of the same scientific family, he usually focuses on Epigenetics, concentrating on Drug discovery and intersecting with Normal cell, Human genetics and Combination therapy.
The concepts of his Retinoic acid study are interwoven with issues in Chordate and Lancelet.
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