William H. Okamura

Research.com Recognitions

• 1998 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia.

  I. Nemere;M.C. Dormanen;M.W. Hammond;W.H. Okamura

  427
  Citations

• Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

  A W Norman;Roger Bouillon;M C Farach-Carson;J E Bishop

  258
  Citations

• Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: a structure-function study.

  Xinde Song;June E. Bishop;William H. Okamura;Anthony W. Norman

  180
  Citations

• Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses.

  Anthony W. Norman;William H. Okamura;Marion W. Hammond;June E. Bishop

  180
  Citations

• Structural requirements for the interaction of 1 alpha, 25-(OH) 2- vitiamin D3 with its chick interestinal receptor system.

  D A Procsal;W H Okamura;A W Norman

  173
  Citations

• 1α,25-Dihydroxy-3-Epi-vitamin D3, a natural metabolite of 1α,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion

  A.J. Brown;C. Ritter;E. Slatopolsky;K.R. Muralidharan

  149
  Citations

• 6.pi.-Electrocyclization of 1-Azatrienes to 1,2-Dihydropyridines

  David F. Maynard;William H. Okamura

  131
  Citations

• Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses.

  A W Norman;W H Okamura;M C Farach-Carson;K Allewaert

  125
  Citations

• Ligands for the vitamin D endocrine system: different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein.

  Anthony W. Norman;Seiichi Ishizuka;William H. Okamura

  119
  Citations

• Studies on vitamin D and its analogs. VIII. Solution conformations of vitamin D3 and 1 alpha, 25-dihydroxyvitamin D3 by high-resolution proton magnetic resonance spectroscopy.

  Richard M. Wing;William H. Okamura;Albert Rego;Marcel R. Pirio

  118
  Citations

• Molecular tools for study of genomic and rapid signal transduction responses initiated by 1α, 25(OH)2-vitamin D3

  Anthony W. Norman;June E. Bishop;Craig M. Bula;Christopher J. Olivera

  116
  Citations

• Vitamin D: Concerning the Relationship Between Molecular Topology and Biological Function

  William H. Okamura;Anthony W. Norman;Richard M. Wing

  116
  Citations

• Profile of ligand specificity of the vitamin D binding protein for 1α,25-dihydroxyvitamin d3 and its analogs

  June E. Bishop;Elaine D. Collins;William H. Okamura;Anthony W. Norman

  116
  Citations

• Vitamin D in solution: conformations of vitamin D3, 1alpha,25-dihydroxyvitamin D3, and dihydrotachysterol3.

  Richard M. Wing;William H. Okamura;Marcel R. Pirio;Steven M. Sine

  113
  Citations

• Chemistry and conformation of vitamin D molecules

  William H. Okamura;M.Mark Midland;Marion W. Hammond;Noorsaadah Abd.Rahman

  113
  Citations

• 1,3,7,9,13,15-Hexadehydro[18]annulene

  William H. Okamura;Franz. Sondheimer

  110
  Citations

• An enantioselective central-axial-central chiral element transfer process leading to a concise synthesis of (+)-sterpurene: Intramolecular Diels-Alder reactions of vinylallene sulfoxides

  Richard A. Gibbs;Karin Bartels;Robert W. K. Lee;William H. Okamura

  105
  Citations

• Different shapes of the steroid hormone 1α,25(OH)2-vitamin D3 act as agonists for two different receptors in the vitamin D endocrine system to mediate genomic and rapid responses☆

  Anthony W. Norman;Helen L. Henry;June E. Bishop;Xin-De Song

  104
  Citations

• Studies of vitamin D (calciferol) and its analogs. 39. Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogs of 1.alpha.,25-dihydroxyvitamin D3

  B. Figadere;A. W. Norman;H. L. Henry;H. P. Koeffler

  103
  Citations

• Rapid and genomic biological responses are mediated by different shapes of the agonist steroid hormone, 1α,25(oh)2vitamin d3

  A. W. Norman;Xinde Song;L. Zanello;C. Bula

  99
  Citations