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Roshantha A. S. Chandraratna

Roshantha A. S. Chandraratna

D-Index & Metrics

Chemistry

D-Index
70
Citations
12101
World Ranking
6058
National Ranking
17

Biology and Biochemistry

D-Index
73
Citations
14969
World Ranking
6073
National Ranking
28

Overview

Roshantha A. S. Chandraratna is affiliated with Allergan (Ireland) and conducts research in Ireland. Their work primarily focuses on immunology, microbiology, and molecular biology, with emphasis on retinoids in leukemia, immune cell function and interaction, and T-cell and B-cell immunology.

The scientist has contributed to the field through publications in recognized venues, including the journal Blood.

  • Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses, 2020, Blood

Frequent co-authors of Roshantha A. S. Chandraratna include:

  • Govindarajan Thangavelu
  • Chao Wang
  • Michaël Loschi
  • Asim Saha
  • Mark J. Osborn

Research topics covered encompass:

  • Retinoids in leukemia and cellular processes
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology

The scientist's main fields of study are:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields include:

  • Immunology
  • Molecular Biology

Best Publications

  • Tazarotene-induced Gene 2 (TIG2), a Novel Retinoid-Responsive Gene in Skin

    Sunil Nagpal;Sheetal Patel;Heidi Jacobe;Daniel DiSepio

  • Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists

    Kengo Shimono;Wei En Tung;Wei En Tung;Christine MacOlino;Amber Hsu Tsai Chi

  • Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.

    Tohru Tsukui;Javier Capdevila;Koji Tamura;Pilar Ruiz-Lozano

  • ACTIVATION OF RETINOID X RECEPTORS INDUCES APOPTOSIS IN HL-60 CELL LINES

    László Nagy;Vilmos A. Thomázy;Gregory L. Shipley;László Fésüs

  • Separation of transactivation and AP1 antagonism functions of retinoic acid receptor alpha.

    Sunil Nagpal;Jyoti Athanikar;Roshantha A.S. Chandraratna

  • BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect.

    Andrew R Hallahan;Andrew R Hallahan;Joel I Pritchard;Roshantha A S Chandraratna;Richard G Ellenbogen

  • Differential Effects of Synthetic Nuclear Retinoid Receptor-selective Retinoids on the Growth of Human Non-Small Cell Lung Carcinoma Cells

    Shi-Yong Sun;Ping Yue;Marcia I. Dawson;Braham Shroot

  • Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid-like activity

    Roshantha A. S. Chandraratna

  • 13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors

    Miki Tsukada;Mandy Schröder;Constantin E. Orfanos;Christos C. Zouboulis

  • Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene

    Daniel DiSepio;Corine Ghosn;Richard L. Eckert;Anne Deucher

  • Vitamin A Enhances in Vitro Th2 Development Via Retinoid X Receptor Pathway

    Charles B. Stephensen;Reuven Rasooly;Xiaowen Jiang;Michael A. Ceddia

  • Tazarotene gel, a new retinoid, for topical therapy of psoriasis: Vehicle-controlled study of safety, efficacy, and duration of therapeutic effect

    Gerald D. Weinstein;Gerald G. Krueger;Nicholas J. Lowe;Madeleine Duvic

  • Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways.

    Andrea D. Weston;Vicki Rosen;Roshantha A.S. Chandraratna;T. Michael Underhill

  • Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor-responsive gene in skin

    Sunil Nagpal;Sheetal Patel;Arisa T. Asano;Alan T. Johnson

  • Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes.

    Ulrich Kintscher;Stephan Goetze;Shu Wakino;Sarah Kim

  • Therapeutic applications for ligands of retinoid receptors.

    Scott M. Thacher;Jayasree Vasudevan;Roshantha A.S. Chandraratna

  • Programmed Cell Death Is Required for Palate Shelf Fusion and Is Regulated by Retinoic Acid

    Rodrigo Cuervo;Concepción Valencia;Roshantha A.S. Chandraratna;Luis Covarrubias

  • Adenomatous Polyposis Coli (APC)-independent Regulation of β-Catenin Degradation via a Retinoid X Receptor-mediated Pathway

    Jia-Hao Xiao;Corine Ghosn;Cory Hinchman;Chad Forbes

  • Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter

    Laszlo Nagy;Margaret Saydak;Nancy Shipley;Shan Lu

  • Response of psoriasis to a new topical retinoid, AGN 190168.

    Teresa Esgleyes-Ribot;Roshantha A. Chandraratna;Deborah A. Lew-Kaya;John Sefton

  • Uso terapeutico de compostos com atividade seletiva semelhante a de agonista sobre receptores rxr de retinóide

    Chandraratna Roshantha A

Frequent Co-Authors

Randolph J. Noelle
Randolph J. Noelle Dartmouth College
Richard L. Eckert
Richard L. Eckert University of Maryland, Baltimore
Peter J. A. Davies
Peter J. A. Davies Texas A&M University
Bruce Blumberg
Bruce Blumberg University of California, Irvine
Madeleine Duvic
Madeleine Duvic The University of Texas MD Anderson Cancer Center
William H. Okamura
William H. Okamura University of California, Riverside
Maurizio Pacifici
Maurizio Pacifici Children's Hospital of Philadelphia
Carl R. Walkley
Carl R. Walkley Hudson Institute of Medical Research
Masahiro Iwamoto
Masahiro Iwamoto University of Maryland, Baltimore
Waun Ki Hong
Waun Ki Hong The University of Texas MD Anderson Cancer Center

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