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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
17495
World Ranking
5399
National Ranking
2560

Overview

Richard L. Eckert is affiliated with the University of Maryland, Baltimore, in the United States. Their research contributions span multiple disciplines within biochemistry, genetics, molecular biology, and medicine.

The main fields of study for Richard L. Eckert include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work further extends into specialized subfields such as:

  • Molecular Biology
  • Cell Biology
  • Pulmonary and Respiratory Medicine
  • Oncology
  • Immunology

Richard L. Eckert's research touches on critical topics including:

  • Blood properties and coagulation
  • Hippo pathway signaling and YAP/TAZ
  • Cancer-related gene regulation
  • Chromatin Remodeling and Cancer
  • Skin and Cellular Biology Research
  • Erythrocyte Function and Pathophysiology
  • Epigenetics and DNA Methylation

Frequent publication venues where their work appears are:

  • Molecular Carcinogenesis
  • Journal of Biological Chemistry
  • Cancer Research
  • Oncogene
  • Molecular Cancer Research

Among recent scientific papers authored are:

  • VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype, 2021, Molecular Carcinogenesis
  • ACTL6A suppresses p21Cip1 expression to enhance the epidermal squamous cell carcinoma phenotype, 2020, Oncogene
  • Structure-activity relationships of N-terminal variants of peptidomimetic tissue transglutaminase inhibitors, 2022, European Journal of Medicinal Chemistry
  • Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity, 2021, Molecular Carcinogenesis
  • Mesothelioma cancer cells are glutamine addicted and glutamine restriction reduces YAP1 signaling to attenuate tumor formation, 2022, Molecular Carcinogenesis

Richard L. Eckert collaborates frequently with several coauthors, including:

  • Gautam Adhikary
  • Wen Xu
  • Suruchi Shrestha
  • Xi Chen
  • Jeffrey W. Keillor

The range and frequency of publications suggest a focus on molecular mechanisms underlying cancer, cell signaling pathways, and gene regulation, with particular attention to the Hippo pathway and YAP/TAZ signaling in cellular and cancer biology contexts.

Best Publications

  • S100 Proteins in the Epidermis

    Richard L. Eckert;Ann-Marie Broome;Monica Ruse;Nancy Robinson

  • Structure and evolution of the human involucrin gene

    Richard L. Eckert;Howard Green

  • The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation

    Richard L. Eckert;James F. Crish;Nancy A. Robinson

  • Transglutaminase Regulation of Cell Function

    Richard L. Eckert;Mari T. Kaartinen;Maria Nurminskaya;Alexey M. Belkin

  • Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

    Jerome F. Sah;Sivaprakasam Balasubramanian;Richard L. Eckert;Ellen A. Rorke

  • S100 Protein Subcellular Localization During Epidermal Differentiation and Psoriasis

    Ann Marie Broome;David Ryan;Richard L. Eckert

  • Structure, function, and differentiation of the keratinocyte

    R. L. Eckert

  • S100A11, S100A10, Annexin I, Desmosomal Proteins, Small Proline-rich Proteins, Plasminogen Activator Inhibitor-2, and Involucrin Are Components of the Cornified Envelope of Cultured Human Epidermal Keratinocytes

    Nancy A. Robinson;Stephan Lapic;Jean F. Welter;Richard L. Eckert

  • Sex Steroids and Growth Factors Differentially Regulate the Growth and Differentiation of Cultured Human Endometrial Stromal Cells

    Juan C. Irwin;Wulf H. Utian;Richard L. Eckert

  • Transglutaminase function in epidermis.

    Richard L. Eckert;Michael T. Sturniolo;Ann Marie Broome;Monica Ruse

  • Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity.

    Jean F. Welter;James F. Crish;Chapla Agarwal;Richard L. Eckert

  • Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene

    Daniel DiSepio;Corine Ghosn;Richard L. Eckert;Anne Deucher

  • The Epidermis: Genes On – Genes Off

    Richard L. Eckert;James F. Crish;Eric B. Banks;Jean F. Welter

  • Involucrin—Structure and Role in Envelope Assembly

    Richard L. Eckert;Michael B. Yaffe;James F. Crish;Shubha Murthy

  • Molecular biology of keratinocyte differentiation.

    Richard Leon Eckert;Ellen Anne Rorke

  • Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway

    Tatiana Efimova;Peter LaCelle;Jean F. Welter;Richard L. Eckert

  • Green Tea Polyphenol Stimulates a Ras, MEKK1, MEK3, and p38 Cascade to Increase Activator Protein 1 Factor-dependent Involucrin Gene Expression in Normal Human Keratinocytes

    Sivaprakasam Balasubramanian;Tatiana Efimova;Richard L. Eckert

  • The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival

    Sivaprakasam Balasubramanian;Gautam Adhikary;Richard L. Eckert

  • Differential expression of the fos and jun family members c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD during human epidermal keratinocyte differentiation.

    Jean F Welter;Richard L. Eckert

  • Physical properties of estrogen receptor complexes in MCF-7 human breast cancer cells. Differences with anti-estrogen and estrogen.

    R L Eckert;B S Katzenellenbogen

Frequent Co-Authors

Chen-Yong Lin
Chen-Yong Lin Georgetown University
H. Richard Alexander
H. Richard Alexander Rutgers, The State University of New Jersey
Gail V. W. Johnson
Gail V. W. Johnson University of Rochester
Peter M. Elias
Peter M. Elias University of California, San Francisco
Kapil Mehta
Kapil Mehta MolQ Laboratory
Miroslav Blumenberg
Miroslav Blumenberg New York University
Thomas S. McCormick
Thomas S. McCormick Case Western Reserve University
Linda Van Horn
Linda Van Horn Northwestern University

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