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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
14898
World Ranking
15958
National Ranking
6627

Overview

Michael D. Johnson is affiliated with Georgetown University in the United States. Their research spans primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Cell Biology, Molecular Biology, Hematology, Oncology, and Genetics.

The scientific contributions of Michael D. Johnson are distributed across topics such as Protease and Inhibitor Mechanisms, Blood Coagulation and Thrombosis Mechanisms, Skin and Cellular Biology Research, Proteoglycans and Glycosaminoglycans Research, Cell Adhesion Molecules Research, Fibroblast Growth Factor Research, and studies related to Coagulation, Bradykinin, Polyphosphates, and Angioedema.

Frequent publication venues for Johnson include:

  • Human Cell
  • PLoS ONE
  • Human Molecular Genetics
  • Nature Communications
  • Frontiers in Pharmacology

The scientist has coauthored extensively with several collaborators, including:

  • Chen-Yong Lin
  • Jehng-Kang Wang
  • Robert B. Barndt
  • Nanxi Huang
  • Dajun D. Lu

Among the recent papers authored or coauthored by Michael D. Johnson are:

  • Screening of GPCR drugs for repurposing in breast cancer, 2022, Frontiers in Pharmacology
  • Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity, 2020, Genes & Diseases
  • The spatiotemporal control of human matriptase action on its physiological substrates: a case against a direct role for matriptase proteolytic activity in profilaggrin processing and desquamation, 2020, Human Cell
  • Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin, 2020, Human Cell
  • Ibrutinib and Venetoclax in Relapsed and Refractory Follicular Lymphoma, 2020, Blood

Best Publications

  • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

    Richard M. Neve;Richard M. Neve;Koei Chin;Jane Fridlyand;Jennifer Yeh

  • Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine

    Vered Stearns;Michael D. Johnson;James M. Rae;James M. Rae;Alan Morocho

  • Pharmacological Characterization of 4-hydroxy- N -desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen

    Michael D. Johnson;Hong Zuo;Kyung Hoon Lee;Joseph P. Trebley

  • Small-molecule agonists for the glucagon-like peptide 1 receptor

    Lotte Bjerre Knudsen;Dan Kiel;Min Teng;Carsten Behrens

  • Matriptase and HAI-1 Are Expressed by Normal and Malignant Epithelial Cells in Vitro and in Vivo

    Michael Oberst;Joanna Anders;Bin Xie;Baljit Singh

  • The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor.

    Michael D. Oberst;Cicely A. Williams;Robert B. Dickson;Michael D. Johnson

  • HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease.

    Michael D. Oberst;Li-Yuan L. Chen;Ken-Ichi Kiyomiya;Cicely A. Williams

  • Characterization of Matriptase expression in normal human tissues

    Michael D. Oberst;Baljit Singh;Metin Ozdemirli;Robert B. Dickson

  • TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells

    Ya-Wen Chen;Ming-Shyue Lee;Amanda Lucht;Feng-Pai Chou

  • Phase II Evaluation of Thalidomide in Patients With Metastatic Breast Cancer

    Said M. Baidas;Eric P. Winer;Gini F. Fleming;Lyndsay Harris

  • Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors

    Chad J. Creighton;Kevin E Cordero;Jose M Larios;Rebecca S Miller

  • The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.

    Hongwei Wang;Hao Li;Linda B. Moore;Michael D. L. Johnson

  • Quantitative Demonstration of Spontaneous Metastasis by MCF-7 Human Breast Cancer Cells Cotransfected with Fibroblast Growth Factor 4 and LacZ

    Junichi Kurebayashi;Sandra W. McLeskey;Michael D. Johnson;Marc E. Lippman

  • Delayed mammary gland involution in MMTV-AKT1 transgenic mice.

    Scott Ackler;Shakeel Ahmad;Christopher Tobias;Michael D Johnson

  • Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells.

    Lynda R. Wiseman;Michael D. Johnson;Alan E. Wakeling;Anne E. Lykkesfeldt

  • Cooperation of TGF alpha and c-Myc in mouse mammary tumorigenesis: coordinated stimulation of growth and suppression of apoptosis.

    Laufey Thora Amundadottir;Sharyl S.J. Nass;Guy Berchem;Michael D L Johnson

  • The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells.

    Erik W. Thompson;Nits Brünner;Jeffrey Torri;Michael D. Johnson

  • GREB1 is a novel androgen-regulated gene required for prostate cancer growth.

    James Michael Rae;Michael D. Johnson;Kevin E. Cordero;Joshua O. Scheys

  • Comprehensive mutation and copy number profiling in archived circulating breast cancer tumor cells documents heterogeneous resistance mechanisms

    Costanza Paoletti;Andi K. Cani;Jose M. Larios;Daniel H. Hovelson

  • Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1.

    Peng Li;Sheng Jiang;Sheau-Ling Lee;Cheng Yong Lin

Frequent Co-Authors

Chen-Yong Lin
Chen-Yong Lin Georgetown University
Robert Clarke
Robert Clarke University of Oxford
Albert J. Fornace
Albert J. Fornace Georgetown University
Erik W. Thompson
Erik W. Thompson Queensland University of Technology
Louis M. Weiner
Louis M. Weiner Georgetown University Medical Center
Erica A. Golemis
Erica A. Golemis Fox Chase Cancer Center
David A. Flockhart
David A. Flockhart Indiana University
Nils Brünner
Nils Brünner University of Copenhagen
Hiroaki Kataoka
Hiroaki Kataoka University of Miyazaki
Marc E. Lippman
Marc E. Lippman National Institutes of Health

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