World's Best Scientists 2026 revealed!
David A. Flockhart

David A. Flockhart

D-Index & Metrics

Medicine

D-Index
93
Citations
30272
World Ranking
10929
National Ranking
5623

David A. Flockhart publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where David A. Flockhart sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 400 publications — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

David A. Flockhart D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where David A. Flockhart sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 93 D-Index — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David A. Flockhart was affiliated with Indiana University in the United States. Their research contributions focused primarily on pharmacology, toxicology, pharmaceutics, medicine, and biochemistry, genetics and molecular biology. The scientist worked mainly within subfields such as pharmacology, biochemistry, pediatrics, perinatology and child health, endocrinology, diabetes and metabolism, and genetics.

Their scholarly work covered topics related to pharmacogenetics and drug metabolism, eicosanoids and hypertension pharmacology, pharmaceutical studies and practices, pharmacological effects and toxicity studies, hormonal regulation and hypertension, estrogen and related hormone effects, and inflammatory mediators and NSAID effects.

Among the research outputs were four papers published in UNC Libraries in 2020. These papers included:

  • In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles (2020, UNC Libraries)
  • Genotype-Guided Tamoxifen Dosing Increases Active Metabolite Exposure in Women With Reduced CYP2D6 Metabolism: A Multicenter Study (2020, UNC Libraries)
  • Creating and evaluating genetic tests predictive of drug response (2020, UNC Libraries)
  • Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity (2020, UNC Libraries)

Frequent collaborators included Howard L. McLeod, Christine M. Walko, Karen E. Weck, Oludamilola Olajide, and Rachel Raab, with whom David A. Flockhart coauthored multiple studies. Most of their works were published in a single primary venue, UNC Libraries.

David A. Flockhart was recognized as a member of the Association of American Physicians, an indication of their standing within the medical research community.

Best Publications

  • CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

    Yan Jin;Zeruesenay Desta;Vered Stearns;Bryan Ward

  • Clinical significance of the cytochrome P450 2C19 genetic polymorphism.

    Zeruesenay Desta;Xiaojiong Zhao;Jae Gook Shin;David A. Flockhart

  • Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine

    Vered Stearns;Michael D. Johnson;James M. Rae;James M. Rae;Alan Morocho

  • Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes

    Matthew P. Goetz;James M. Rae;Vera J. Suman;Stephanie L. Safgren

  • Association of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor-2 Genetic Polymorphisms With Outcome in a Trial of Paclitaxel Compared With Paclitaxel Plus Bevacizumab in Advanced Breast Cancer: ECOG 2100

    Bryan P. Schneider;Molin Wang;Milan Radovich;George W. Sledge

  • Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

    Zeruesenay Desta;Bryan A. Ward;Nadia V. Soukhova;David A. Flockhart

  • The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

    Bryan A. Ward;J. Christopher Gorski;David R. Jones;Stephen D. Hall

  • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.

    Matthew P. Goetz;Stacey K. Knox;Vera J. Suman;James M. Rae

  • Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment.

    Silvana Borges;Zeruesenay Desta;Lang Li;Todd C Skaar

  • Pharmacological Characterization of 4-hydroxy- N -desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen

    Michael D. Johnson;Hong Zuo;Kyung Hoon Lee;Joseph P. Trebley

  • Studies on the properties and mode of action of the purified regulatory subunit of bovine heart adenosine 3':5'-monophosphate-dependent protein kinase.

    Corbin Jd;Sugden Ph;West L;Flockhart Da

  • Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

    Russell A. Wilke;Debbie W. Lin;Dan M. Roden;Paul B. Watkins

  • Rifampin Is a Selective, Pleiotropic Inducer of Drug Metabolism Genes in Human Hepatocytes: Studies with cDNA and Oligonucleotide Expression Arrays

    James M. Rae;Michael D. Johnson;Marc E. Lippman;David A. Flockhart

  • Predictors of Aromatase Inhibitor Discontinuation as a Result of Treatment-Emergent Symptoms in Early-Stage Breast Cancer

    N. Lynn Henry;Faouzi Azzouz;Zereunesay Desta;Lang Li

  • Interethnic Differences in Genetic Polymorphisms of CYP2D6 in the U.S. Population: Clinical Implications

    Stephen Bernard;Kathleen A. Neville;Anne T. Nguyen;David A. Flockhart

  • Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen

    Young Chai Lim;Zeruesenay Desta;David A. Flockhart;Todd C. Skaar

  • Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants.

    Jose E. Tanus-Santos;Mehul Desai;David A. Flockhart

  • Pharmacogenomics: Challenges and Opportunities

    Dan M. Roden;Russ B. Altman;Neal L. Benowitz;David A. Flockhart

  • The pharmacogenetics research network: from SNP discovery to clinical drug response.

    K M Giacomini;C M Brett;R B Altman;N L Benowitz

  • Inhibition of IL-12 production by thalidomide.

    David R. Moller;Maria Wysocka;Brian M. Greenlee;Xiaojing Ma

Frequent Co-Authors

Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor
Vered Stearns
Vered Stearns Johns Hopkins University
Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition
Matthew P. Goetz
Matthew P. Goetz Mayo Clinic
Howard L. McLeod
Howard L. McLeod Utah Tech University
Steffi Oesterreich
Steffi Oesterreich University of Pittsburgh
Russ B. Altman
Russ B. Altman Stanford University

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Best Scientists Citing David A. Flockhart