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Biology and Biochemistry

D-Index
69
Citations
16237
World Ranking
7428
National Ranking
3388

Overview

Steffi Oesterreich is affiliated with the University of Pittsburgh in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a significant emphasis on medicine. Within these domains, their work extensively covers oncology, cancer research, molecular biology, genetics, and pulmonary and respiratory medicine.

Their research topics center on breast cancer treatment studies, cancer genomics and diagnostics, cancer cells and metastasis, estrogen and related hormone effects, breast lesions and carcinomas, advanced breast cancer therapies, and global cancer incidence and screening.

Several frequent co-authors appear in their publications, including Adrian V. Lee, Jennifer M. Atkinson, George C. Tseng, Zheqi Li, and Peter C. Lucas. Oesterreich's research has been published in a variety of venues, with the highest number of articles appearing in Cancer Research, followed by bioRxiv (Cold Spring Harbor Laboratory), npj Breast Cancer, Annals of Oncology, and Clinical Cancer Research.

Recent papers authored or co-authored by Steffi Oesterreich include:

  • Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer, 2020, Immunity
  • A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology, 2022, Nature Cancer
  • The Great Immune Escape: Understanding the Divergent Immune Response in Breast Cancer Subtypes, 2022, Cancer Discovery
  • Pan-Cancer Analysis of BRCA1 and BRCA2 Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity, 2020, JCO Precision Oncology
  • FGFR4: A promising therapeutic target for breast cancer and other solid tumors, 2020, Pharmacology & Therapeutics

Best Publications

  • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.

    Giovanni Ciriello;Giovanni Ciriello;Michael L. Gatza;Michael L. Gatza;Andrew H. Beck;Matthew D. Wilkerson

  • Biological and Clinical Implications of Heat Shock Protein 27000 (Hsp27): a Review

    Daniel R. Ciocca;Steffi Oesterreich;Gary C. Chamness;William L. MCGuire

  • Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer

    Anthony R. Cillo;Cornelius H.L. Kürten;Cornelius H.L. Kürten;Tracy Tabib;Zengbiao Qi

  • MCF-7 Cells—Changing the Course of Breast Cancer Research and Care for 45 Years

    Adrian V. Lee;Steffi Oesterreich;Nancy E. Davidson

  • An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer.

    Qiu-Xia Zhang;Ake Borg;Douglas M. Wolf;Steffi Oesterreich

  • B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

    Ayana T. Ruffin;Anthony R. Cillo;Tracy Tabib;Angen Liu

  • The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines

    S. Oesterreich;Chye-Ning Weng;Ming Qiu;S. G. Hilsenbeck

  • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.

    Xiaojiang Cui;Ping Zhang;Wanleng Deng;Steffi Oesterreich

  • Sensitive detection of mono- and polyclonal ESR1 mutations in primary tumors, metastatic lesions and cell free DNA of breast cancer patients

    Peilu Wang;Amir Bahreini;Rekha Gyanchandani;Peter C. Lucas

  • Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth.

    Steffi Oesterreich;Ping Zhang;Rebecca L. Guler;Xiuhua Sun

  • Cross-Talk among Estrogen Receptor, Epidermal Growth Factor, and Insulin-like Growth Factor Signaling in Breast Cancer

    Adrian V. Lee;Xiaojiang Cui;Steffi Oesterreich

  • Estrogen receptor corepressors -- a role in human breast cancer?

    K. M. Dobrzycka;S. M. Townson;S. Jiang;Steffi Oesterreich

  • Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade.

    Ye Qin;Shauna N. Vasilatos;Lin Chen;Hao Wu

  • Epigenetics in breast cancer: what's new?

    Yi Huang;Shweta Nayak;Rachel Jankowitz;Nancy E Davidson

  • Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.

    Nolan Priedigkeit;Ryan J. Hartmaier;Yijing Chen;Damir Vareslija

  • Hsp27 overexpression inhibits doxorubicin–induced apoptosis in human breast cancer cells

    Rhonda K. Hansen;Irma Parra;Pierre Lemieux;Steffi Oesterreich

  • Estrogen-mediated down-regulation of E-cadherin in breast cancer cells.

    Steffi Oesterreich;Wanleng Deng;Shiming Jiang;Xiaojiang Cui

  • Quercetin Inhibits Heat Shock Protein Induction but Not Heat Shock Factor DNA-Binding in Human Breast Carcinoma Cells

    R.K. Hansen;S. Oesterreich;S. Oesterreich;P. Lemieux;P. Lemieux;K.D. Sarge;K.D. Sarge

  • Hormone response in ovarian cancer: time to reconsider as a clinical target?

    Francesmary Modugno;Robin A Laskey;Ashlee L Smith;Courtney Lynn Andersen

  • Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response

    Matthew J. Sikora;Kristine L. Cooper;Amir Bahreini;Soumya Luthra

Frequent Co-Authors

George C. Tseng
George C. Tseng University of Pittsburgh
Adam Brufsky
Adam Brufsky University of Pittsburgh
Nancy E. Davidson
Nancy E. Davidson University of Washington
Suzanne A. W. Fuqua
Suzanne A. W. Fuqua Baylor College of Medicine
Vered Stearns
Vered Stearns Johns Hopkins University
David A. Flockhart
David A. Flockhart Indiana University
Susan G. Hilsenbeck
Susan G. Hilsenbeck Baylor College of Medicine
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor
Alana L. Welm
Alana L. Welm University of Utah
Ronald L. Hamilton
Ronald L. Hamilton University of Pittsburgh

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