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Molecular Biology

D-Index
77
Citations
25442
World Ranking
1100
National Ranking
36

Research.com Recognitions

  • 2015 - Fellow of the Royal Society of Canada Academy of Science

Overview

James R. Davie is affiliated with the University of Manitoba in Canada. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology as evidenced by a majority of their publications in this subfield.

The scientist's work covers several interconnected topics, including:

  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • SARS-CoV-2 and COVID-19 Research
  • Genetics and Neurodevelopmental Disorders
  • COVID-19 Clinical Research Studies

Their recent publications demonstrate a focus on epigenetics and disease mechanisms, with several papers addressing chromatin modifications and viral interactions:

  • "The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes," 2021, Clinical Epigenetics
  • "Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus," 2020, Genome
  • "SARS-CoV-2 multifaceted interaction with the human host. Part II: Innate immunity response, immunopathology, and epigenetics," 2020, IUBMB Life
  • "Genomic landscape of transcriptionally active histone arginine methylation marks, H3R2me2s and H4R3me2a, relative to nucleosome depleted regions," 2020, Gene
  • "The chicken model organism for epigenomic research," 2020, Genome

Among the frequent co-authors collaborating with James R. Davie are:

  • Tasnim H. Beacon
  • Ted M. Lakowski
  • Mojgan Rastegar
  • Camila López
  • Geneviève P. Delcuve

Their work has been published repeatedly in several scientific venues, indicating ongoing contributions to these journals:

  • Genome
  • Biochemistry and Cell Biology
  • IUBMB Life
  • Gene
  • International Journal of Molecular Sciences

In recognition of their scientific contributions, James R. Davie was named a Fellow of the Royal Society of Canada in 2015 within the Academy of Science.

Best Publications

  • Histone H4-K16 Acetylation Controls Chromatin Structure and Protein Interactions

    Michael Shogren-Knaak;Haruhiko Ishii;Jian-Min Sun;Michael J. Pazin

  • A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.

    Thorsten Heinzel;Robert M. Lavinsky;Tina-Marie Mullen;Mats Söderström

  • Inhibition of Histone Deacetylase Activity by Butyrate

    James R. Davie

  • Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

    Carol D Laherty;Wen-Ming Yang;Jian-Min Sun;James R Davie

  • Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family

    Wen-Ming Yang;Ya-Li Yao;Jian-Min Sun;James R. Davie

  • ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors

    Bart Lutterbach;Jennifer J. Westendorf;Bryan Linggi;Andrea Patten

  • Gene regulation by Sp1 and Sp3.

    Lin Li;Shihua He;Jian-Min Sun;James R Davie

  • Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

    Geneviève P Delcuve;Dilshad H Khan;James R Davie

  • Regulation of neuronal traits by a novel transcriptional complex.

    Nurit Ballas;Elena Battaglioli;Fouad Atouf;Maria E. Andres

  • Epigenetic control

    Geneviève P. Delcuve;Mojgan Rastegar;James R. Davie

  • Role of covalent modifications of histones in regulating gene expression

    Virginia A Spencer;James R Davie

  • The Human Factors YY1 and LSF Repress the Human Immunodeficiency Virus Type 1 Long Terminal Repeat via Recruitment of Histone Deacetylase 1

    Jason J. Coull;Fabio Romerio;Jian Min Sun;Janet L. Volker

  • The role of Sp1 and Sp3 in normal and cancer cell biology

    Lin Li;James R. Davie

  • Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts.

    D N Chadee;M J Hendzel;C P Tylipski;C D Allis

  • Direct Visualization of the Human Estrogen Receptor α Reveals a Role for Ligand in the Nuclear Distribution of the Receptor

    Han Htun;Laurel T. Holth;Dawn Walker;James R. Davie

  • The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.

    Katherine L Dunn;Paula S Espino;Bojan Drobic;Shihua He

  • Covalent modifications of histones: expression from chromatin templates.

    James R Davie

  • SAP30, a Component of the mSin3 Corepressor Complex Involved in N-CoR-Mediated Repression by Specific Transcription Factors

    Carol D. Laherty;Andrew N. Billin;Robert M. Lavinsky;Gregory S. Yochum

  • Chromatin immunoprecipitation: a tool for studying histone acetylation and transcription factor binding.

    Virginia A Spencer;Jian-Min Sun;Lin Li;James R Davie

  • 5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA.

    J H Proffitt;J R Davie;D Swinton;S Hattman

Frequent Co-Authors

Leigh C. Murphy
Leigh C. Murphy University of Manitoba
Edward Seto
Edward Seto George Washington University
Lorrie A. Kirshenbaum
Lorrie A. Kirshenbaum University of Manitoba
Michael G. Rosenfeld
Michael G. Rosenfeld University of California, San Diego
Michael J. Hendzel
Michael J. Hendzel University of Alberta
C. David Allis
C. David Allis Rockefeller University
David W. Rose
David W. Rose University of California, San Diego
Christopher K. Glass
Christopher K. Glass University of California, San Diego
Steffi Oesterreich
Steffi Oesterreich University of Pittsburgh
Robert N. Eisenman
Robert N. Eisenman Fred Hutchinson Cancer Research Center

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