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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
179
Citations
161421
World Ranking
624
National Ranking
390

Biology and Biochemistry

D-Index
181
Citations
163776
World Ranking
66
National Ranking
55

Medicine

D-Index
179
Citations
161620
World Ranking
375
National Ranking
237

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2017 - Member of the National Academy of Sciences
  • 2015 - Member of the National Academy of Medicine (NAM)
  • 2014 - Fellow of the American Academy of Arts and Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Christopher K. Glass is affiliated with the University of California, San Diego in the United States. Their research spans biochemistry, genetics, and molecular biology, with extensive work in medicine. The scientist's key areas of study include molecular biology, immunology, neurology, physiology, and cancer research.

Their research topics focus on multiple complex biological and medical issues: neuroinflammation and neurodegeneration mechanisms, immune cells in cancer, epigenetics and DNA methylation, single-cell and spatial transcriptomics, genomics and chromatin dynamics, Alzheimer's disease research and treatments, and liver disease diagnosis and treatment.

Recent published papers demonstrate engagement with cutting-edge molecular and cellular research. These include:

  • "Microglia states and nomenclature: A field at its crossroads," 2022, published in Neuron
  • "Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics," 2020, published in Circulation Research
  • "Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis," 2020, published in Immunity
  • "APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia," 2024, published in Nature
  • "Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients," 2021, published in Cell stem cell

Frequent co-authors collaborating with Christopher K. Glass comprise Johannes C. M. Schlachetzki, Nathanael J. Spann, Claudia Z. Han, Ty D. Troutman, and Mashito Sakai, reflecting a network of sustained research partnerships.

Publication venues regularly selected for disseminating research findings include bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, Immunity, Proceedings of the National Academy of Sciences, and Cell Reports.

Christopher K. Glass has been recognized through professional memberships and honors including:

  • Member of the National Academy of Sciences (2017)
  • Member of the National Academy of Medicine (NAM) (2015)
  • Fellow of the American Academy of Arts and Sciences (2014)
  • Member of the Association of American Physicians

Best Publications

  • Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

    Sven Heinz;Christopher Benner;Nathanael Spann;Eric Bertolino

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Ewan Birney;John A. Stamatoyannopoulos;Anindya Dutta;Roderic Guigó

  • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

    Mercedes Ricote;Andrew C. Li;Andrew C. Li;Timothy M. Willson;Carolyn J. Kelly

  • Atherosclerosis: The Road Ahead

    Christopher K. Glass;Joseph L. Witztum

  • Mechanisms underlying inflammation in neurodegeneration.

    Christopher K. Glass;Kaoru Saijo;Beate Winner;Maria Carolina Marchetto

  • A comprehensive classification system for lipids

    Eoin Fahy;Shankar Subramaniam;H. Alex Brown;Christopher K. Glass

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • Macrophages, Inflammation, and Insulin Resistance

    Jerrold M. Olefsky;Christopher K. Glass

  • The coregulator exchange in transcriptional functions of nuclear receptors

    Christopher K. Glass;Michael G. Rosenfeld

  • A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

    Yasutomi Kamei;Lan Xu;Thorsten Heinzel;Joseph Torchia

  • Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

    Andreas J. Hörlein;Anders M. Näär;Thorsten Heinzel;Joseph Torchia

  • Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

    R T Nolte;G B Wisely;S Westin;J E Cobb

  • The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

    Joseph Torchia;David W. Rose;Juan Inostroza;Yasutomi Kamei

  • A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.

    Thorsten Heinzel;Robert M. Lavinsky;Tina-Marie Mullen;Mats Söderström

  • 15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

    Daniel S. Straus;Gabriel Pascual;Mei Li;John S. Welch

  • A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

    Gabriel Pascual;Amy L. Fong;Sumito Ogawa;Amir Gamliel

  • LMSD: LIPID MAPS structure database.

    Manish Sud;Eoin Fahy;Dawn Cotter;Alex Brown

  • Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

    David Gosselin;Verena M. Link;Casey E. Romanoski;Gregory J. Fonseca

  • RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

    Victor C. Yu;Claude Delsert;Bogi Andersen;Jeffrey M. Holloway

  • Microglial cell origin and phenotypes in health and disease.

    Kaoru Saijo;Christopher K. Glass

Frequent Co-Authors

Michael G. Rosenfeld
Michael G. Rosenfeld University of California, San Diego
Christopher Benner
Christopher Benner University of California, San Diego
David W. Rose
David W. Rose University of California, San Diego
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
Shankar Subramaniam
Shankar Subramaniam University of California, San Diego
Edward A. Dennis
Edward A. Dennis University of California, San Diego
Bing Ren
Bing Ren New York Genome Center
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Victor Nizet
Victor Nizet University of California, San Diego

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