World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
114
Citations
57830
World Ranking
651
National Ranking
273

Biology and Biochemistry

D-Index
120
Citations
63160
World Ranking
628
National Ranking
400

Research.com Recognitions

  • 1984 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1983 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Edward A. Dennis is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with notable work also in Medicine.

The scientist's subfields of study include Molecular Biology, Biochemistry, Spectroscopy, Nutrition and Dietetics, and Physiology. These areas reflect their comprehensive approach to studying biological systems at molecular and biochemical levels.

Their main topics of research cover various aspects of lipid science and cellular regulation, including:

  • Metabolomics and Mass Spectrometry Studies
  • Lipid Membrane Structure and Behavior
  • Protein Kinase Regulation and GTPase Signaling
  • Lipid metabolism and biosynthesis
  • Peroxisome Proliferator-Activated Receptors
  • Advanced Proteomics Techniques and Applications
  • Fatty Acid Research and Health

Frequent publication venues for their work include:

  • Journal of Lipid Research
  • Nature Communications
  • The FASEB Journal
  • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Proceedings of the National Academy of Sciences

Frequent collaborators in their research projects have included Daiki Hayashi, Oswald Quehenberger, Aaron M. Armando, Varnavas D. Mouchlis, and Valerie B. O'Donnell.

Some representative recent publications authored or co-authored by Edward A. Dennis are:

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures, 2020, Journal of Lipid Research
  • Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?, 2020, Scientific Reports
  • LIPID MAPS: update to databases and tools for the lipidomics community, 2023, Nucleic Acids Research
  • Quality control requirements for the correct annotation of lipidomics data, 2021, Nature Communications
  • A global lipid map defines a network essential for Zika virus replication, 2020, Nature Communications

Edward A. Dennis was recognized as a Fellow of the American Association for the Advancement of Science in 1984 and as a Fellow of the John Simon Guggenheim Memorial Foundation in 1983. These honors mark significant milestones in their scientific career.

Best Publications

  • A comprehensive classification system for lipids

    Eoin Fahy;Shankar Subramaniam;H. Alex Brown;Christopher K. Glass

  • Diversity of group types, regulation, and function of phospholipase A2.

    E A Dennis

  • Update of the LIPID MAPS comprehensive classification system for lipids

    Eoin Fahy;Shankar Subramaniam;Robert C. Murphy;Masahiro Nishijima

  • The expanding superfamily of phospholipase A(2) enzymes: classification and characterization.

    David A Six;Edward A Dennis

  • Eicosanoid storm in infection and inflammation.

    Edward A. Dennis;Paul C. Norris

  • LMSD: LIPID MAPS structure database.

    Manish Sud;Eoin Fahy;Dawn Cotter;Alex Brown

  • Lipidomics reveals a remarkable diversity of lipids in human plasma

    Oswald Quehenberger;Aaron M. Armando;Alex H. Brown;Stephen B. Milne

  • Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.

    Edward A. Dennis;Jian Cao;Yuan-Hao Hsu;Victoria Magrioti

  • The phospholipase A2 superfamily and its group numbering system

    Ralph H. Schaloske;Edward A. Dennis

  • The growing phospholipase A2 superfamily of signal transduction enzymes

    Edward A. Dennis

  • Phospholipase A2 structure/function, mechanism, and signaling

    John E. Burke;Edward A. Dennis

  • Solubilization of phospholipids by detergents. Structural and kinetic aspects.

    Dov Lichtenberg;Robert J. Robson;Edward A. Dennis

  • Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.

    Sohvi Hörkkö;David A. Bird;Elizabeth Miller;Hiroyuki Itabe

  • REGULATION AND INHIBITION OF PHOSPHOLIPASE A2

    Jesús Balsinde;María A. Balboa;Paul A. Insel;Edward A. Dennis

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

    Gerhard Liebisch;Eoin Fahy;Junken Aoki;Edward A. Dennis

  • Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids.

    F F Davidson;E A Dennis;M Powell;J R Glenney

  • Role of phospholipase in generating lipid second messengers in signal transduction.

    Edward A. Dennis;Sue Goo Rhee;M. Motasim Billah;Yusuf A. Hannun

  • Phospholipase A2 regulation of arachidonic acid mobilization

    Jesús Balsinde;Michelle V Winstead;Edward A Dennis

  • Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition

    Mi-Kyung Chang;Claes Bergmark;Aino Laurila;Sohvi Hörkkö

  • Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

    Nathanael J. Spann;Lana X. Garmire;Jeffrey G. McDonald;David S. Myers

  • The size, shape, and hydration of nonionic surfactant micelles. Triton X-100

    Robert J. Robson;Edward A. Dennis

Frequent Co-Authors

Oswald Quehenberger
Oswald Quehenberger University of California, San Diego
Jesús Balsinde
Jesús Balsinde Spanish National Research Council
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
George Kokotos
George Kokotos National and Kapodistrian University of Athens
Shankar Subramaniam
Shankar Subramaniam University of California, San Diego
María A. Balboa
María A. Balboa Spanish National Research Council
Christopher K. Glass
Christopher K. Glass University of California, San Diego
Robert C. Murphy
Robert C. Murphy University of Colorado Denver
Tony L. Yaksh
Tony L. Yaksh University of California, San Diego
J. Andrew McCammon
J. Andrew McCammon University of California, San Diego

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