World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
23343
World Ranking
2749
National Ranking
2

Overview

Bruno Lomonte is affiliated with the University of Costa Rica in Costa Rica. Their research predominantly focuses on the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. Within these main fields, they have a significant presence in subfields including Genetics, Molecular Biology, Virology, Paleontology, and Global and Planetary Change.

Lomonte's work covers a variety of topics related mostly to venomous animal envenomation and studies, alongside areas such as rabies epidemiology and control, ion channel regulation and function, marine invertebrate physiology and ecology, amphibian and reptile biology, biochemical and structural characterization, and healthcare and venom research.

Their frequent publication venues reflect a consistent focus on toxinology and related biological sciences, with numerous publications appearing in:

  • Toxicon
  • Journal of Proteomics
  • Toxins
  • Biochimie
  • Acta Tropica

Collaboration is a strong aspect of Lomonte's research, with frequent coauthors including:

  • Julián Fernández
  • José María Gutiérrez
  • Mahmood Sasa
  • Juan J. Calvete
  • Fabián Bonilla

Selected recent publications by Lomonte include:

  • "Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms," 2020, Toxins
  • "Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes," 2023, Nature Communications
  • "Development of Nanobodies Against Hemorrhagic and Myotoxic Components of Bothrops atrox Snake Venom," 2020, Frontiers in Immunology
  • "Unity Makes Strength: Exploring Intraspecies and Interspecies Toxin Synergism between Phospholipases A2 and Cytotoxins," 2020, Frontiers in Pharmacology
  • "Novel Snakebite Therapeutics Must Be Tested in Appropriate Rescue Models to Robustly Assess Their Preclinical Efficacy," 2020, Toxins

The work of Bruno Lomonte reflects a systematic approach to understanding toxin effects and therapeutic interventions, with a research career marked by notable contributions to venom research as well as broader molecular and genetic studies.

Best Publications

  • Phospholipase A2 myotoxins from Bothrops snake venoms

    José María Gutiérrez;Bruno Lomonte

  • Venoms, venomics, antivenomics

    Juan J. Calvete;Libia Sanz;Yamileth Angulo;Bruno Lomonte

  • An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action.

    Bruno Lomonte;Yamileth Angulo;Leonel Calderón

  • Host response to Bothrops asper snake venom. Analysis of edema formation, inflammatory cells, and cytokine release in a mouse model.

    Bruno Lomonte;Andrej Tarkowski;Lars Ake Hanson

  • Neutralizing interaction between heparins and myotoxin II, a lysine 49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling.

    B Lomonte;E Moreno;A Tarkowski;L A Hanson

  • Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action

    Cesare Montecucco;Cesare Montecucco;José María Gutiérrez;Bruno Lomonte

  • Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America

    Juan J Calvete;Libia Sanz;Pedro Cid;Pilar de la Torre

  • Medicinal Plants with Inhibitory Properties Against Snake Venoms

    Andreimar Martins Soares;Fábio K. Ticli;Silvana Marcussi;Miriam V. Lourenço

  • Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins

    José María Gutiérrez;Bruno Lomonte

  • A new muscle damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo).

    Bruno Lomonte;José María Gutiérrez

  • Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

    Juan J. Calvete;Libia Sanz;Alicia Pérez;Adolfo Borges

  • Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom--synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region

    Leandro Páramo;Bruno Lomonte;Javier Pizarro-Cerdá;José-Antonio Bengoechea

  • Snake venomics and antivenomics : Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming

    José María Gutiérrez;Bruno Lomonte;Guillermo León;Alberto Alape-Girón

  • Local tissue damage induced by Bothrops snake venoms - A review

    José María Gutiérrez;Bruno Lomonte

  • Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation.

    José María Gutiérrez;Guillermo León;Bruno Lomonte

  • Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom

    José María Gutiérrez;Guillermo León;Gustavo Rojas;Bruno Lomonte

  • Myotoxin II from Bothrops asper (terciopelo) venom is a lysine-49 phospholipase A2

    Brian Francis;Jose Maria Gutierrez;Bruno Lomonte;Ivan I. Kaiser

  • Myotoxic phospholipases A2 in Bothrops snake venoms: Effect of chemical modifications on the enzymatic and pharmacological properties of bothropstoxins from Bothrops jararacussu

    Silvia H. Andrião-Escarso;Andreimar Martins Soares;Andreimar Martins Soares;Veridiana M. Rodrigues;Yamileth Angulo

  • Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism

    Vitelbina Núñez;Pedro Cid;Libia Sanz;Pilar De La Torre

  • Snake venom Lys49 myotoxins: From phospholipases A2 to non-enzymatic membrane disruptors

    Bruno Lomonte;José Rangel

Frequent Co-Authors

José María Gutiérrez
José María Gutiérrez University of Costa Rica
Juan J. Calvete
Juan J. Calvete Spanish National Research Council
Yamileth Angulo
Yamileth Angulo University of Costa Rica
Libia Sanz
Libia Sanz Spanish National Research Council
Alexandra Rucavado
Alexandra Rucavado University of Costa Rica
Edgardo Moreno
Edgardo Moreno National University of Costa Rica
Lars Å. Hanson
Lars Å. Hanson University of Gothenburg
Cesare Montecucco
Cesare Montecucco University of Padua
Andrej Tarkowski
Andrej Tarkowski University of Gothenburg
Ole Lund
Ole Lund Danish National Genome Center

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