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Ana M. Moura-da-Silva

Ana M. Moura-da-Silva

D-Index & Metrics

Molecular Biology

D-Index
47
Citations
3481
World Ranking
2763
National Ranking
5

Overview

Ana M. Moura-da-Silva is affiliated with the Instituto Butantan in Brazil. Their research primarily focuses on venomous animal envenomation and studies, with significant contributions in biochemistry, genetics, and molecular biology as well as immunology and microbiology.

The main topics covered in their work include:

  • Venomous Animal Envenomation and Studies
  • Rabies epidemiology and control
  • Amphibian and Reptile Biology
  • Marine Invertebrate Physiology and Ecology
  • Biochemical and Structural Characterization
  • Yersinia bacterium, plague, ectoparasites research
  • Toxin Mechanisms and Immunotoxins

The scientist's primary fields are further subdivided into subfields such as genetics, virology, paleontology, global and planetary change, and molecular biology. The breadth of their research displays an interdisciplinary approach connecting molecular biology techniques with ecological and epidemiological studies.

Ana M. Moura-da-Silva has authored numerous publications in several journals, with frequent contributions to:

  • Toxins
  • Toxicon
  • Frontiers in Immunology
  • PLoS Neglected Tropical Diseases
  • Toxicology Letters

Notable recent papers include:

  • "Phylogenetically diverse diets favor more complex venoms in North American pitvipers," 2021, Proceedings of the National Academy of Sciences
  • "Bothrops atrox, the most important snake involved in human envenomings in the amazon: How venomics contributes to the knowledge of snake biology and clinical toxinology," 2020, Toxicon X
  • "Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca genome," 2021, Proceedings of the National Academy of Sciences
  • "Plant-Derived Toxin Inhibitors as Potential Candidates to Complement Antivenom Treatment in Snakebite Envenomations," 2022, Frontiers in Immunology
  • "Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom," 2020, Toxins

The scientist collaborates frequently with other researchers. Some of the most frequent co-authors include:

  • Wuelton Marcelo Monteiro
  • Jacqueline de Almeida Gonçalves Sachett
  • Luciana Aparecida Freitas-de-Sousa
  • Felipe G. Grazziotin
  • Fan Hui Wen

This network of collaboration reflects active participation in advancing the understanding of venom biology and toxinology through multidisciplinary research efforts. Their work bridges molecular genetics, clinical toxinology, and immunology, contributing to the broader field of venomous animals and related public health concerns.

Best Publications

  • Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

    Juan J. Calvete;Libia Sanz;Alicia Pérez;Adolfo Borges

  • Processing of pro-tumor necrosis factor-alpha by venom metalloproteinases: a hypothesis explaining local tissue damage following snake bite.

    Ana Maria Moura-da-Silva;Gavin David Laing;Mark John Ingraham Paine;Jeremy Michael Thomas Jonathan Dennison

  • Clinical trial of two antivenoms for the treatment of Bothrops and Lachesis bites in the north eastern Amazon region of Brazil.

    Pedro Pereira de Oliveira Pardal;Suzana Medeiro Souza;Maria Rita de Cássia da Costa Monteiro;Hui Wen Fan

  • Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: A biochemical and immunohistochemical study

    Teresa Escalante;John Shannon;Ana M. Moura-da-Silva;José María Gutiérrez

  • Natterins, a new class of proteins with kininogenase activity characterized from Thalassophryne nattereri fish venom.

    G.S. Magalhães;M. Lopes-Ferreira;I.L.M. Junqueira-de-Azevedo;P.J. Spencer

  • Inflammatory pathogenesis of snake venom metalloproteinase-induced skin necrosis.

    Gavin David Laing;Patricia Bianca Clissa;Robert David Geoffrey Theakston;Ana Maria Moura-da-Silva

  • Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species.

    L.A. Freitas-de-Sousa;D.R. Amazonas;L.F. Sousa;S.S. Sant'Anna

  • BnP1, a novel P-I metalloproteinase from Bothrops neuwiedi venom: biological effects benchmarking relatively to jararhagin, a P-III SVMP.

    C. Baldo;I. Tanjoni;I.R. León;I.F.C. Batista

  • Isolation and comparison of myotoxins isolated from venoms of different species of bothrops snakes

    A.M. Moura-da-Silva;H. Desmond;G. Laing;R.D.G. Theakston

  • Collagen-induced secretion-dependent phase of platelet aggregation is inhibited by the snake venom metalloproteinase jararhagin

    A. S. Kamiguti;A. M. Moura-Da-Silva;A. M. Moura-Da-Silva;G. D. Laing;T. Knapp

  • Evidence for heterogeneous forms of the snake venom metalloproteinase jararhagin: a factor contributing to snake venom variability.

    A.M Moura-da-Silva;M.S Della-Casa;A.S David;M.T Assakura

  • Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation

    Juliana L. Bernardoni;Leijiane F. Sousa;Luciana S. Wermelinger;Aline S. Lopes

  • Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases.

    A.M. Moura-da-Silva;O.H.P. Ramos;C. Baldo;S. Niland

  • Transcriptome analysis of expressed sequence tags from the venom glands of the fish Thalassophryne nattereri.

    G.S. Magalhães;I.L.M. Junqueira-de-Azevedo;M. Lopes-Ferreira;D.M. Lorenzini

  • The molecular cloning of a phospholipase A2 from Bothrops jararacussu snake venom: evolution of venom group II phospholipase A2's may imply gene duplications.

    Ana M. Moura-da-Silva;Ana M. Moura-da-Silva;Mark J. I. Paine;Marcelo R. V. Diniz;R. David G. Theakston

  • Jararhagin ECD-Containing Disintegrin Domain: Expression in Escherichia coli and Inhibition of the Platelet–Collagen Interaction

    A. M. Moura-Da-Silva;A. Linica;M. S. Della-Casa;A. S. Kamiguti

  • Cloning of metalloprotease genes in the carpet viper (Echis pyramidum leakeyi). Further members of the metalloprotease/disintegrin gene family.

    Mark J. I. Paine;Ana M. Moura-Da-Silva;Ana M. Moura-Da-Silva;R. David G. Theakston;Julian M. Crampton

  • Importance of metalloproteinases and macrophages in viper snake envenomation-induced local inflammation.

    E. P. Costa;P. B. Clissa;C. F. P. Teixeira;A. M. Moura-da-Silva

  • Structural and biological characterization of Nattectin, a new C-type lectin from the venomous fish Thalassophryne nattereri

    Mônica Lopes-Ferreira;Geraldo Santana Magalhães;Jorge Hernandez Fernandez;Inácio de Loiola M. Junqueira-de-Azevedo

  • Thalassophryne nattereri fish venom: biological and biochemical characterization and serum neutralization of its toxic activities

    M Lopes-Ferreira;K.C Barbaro;D.F Cardoso;A.M Moura-Da-Silva

Frequent Co-Authors

Mark J. I. Paine
Mark J. I. Paine Liverpool School of Tropical Medicine
José María Gutiérrez
José María Gutiérrez University of Costa Rica
H. Lisle Gibbs
H. Lisle Gibbs The Ohio State University
R.D.G. Theakston
R.D.G. Theakston Liverpool School of Tropical Medicine
Jay W. Fox
Jay W. Fox University of Virginia
Yamileth Angulo
Yamileth Angulo University of Costa Rica
Carol V. Robinson
Carol V. Robinson University of Oxford
Bruno Lomonte
Bruno Lomonte University of Costa Rica
Bryan G. Fry
Bryan G. Fry University of Queensland
Antonio C. Marques
Antonio C. Marques Universidade de São Paulo

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