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Kazuhisa Sekimizu

Kazuhisa Sekimizu

D-Index & Metrics

Molecular Biology

D-Index
64
Citations
17195
World Ranking
1726
National Ranking
143

Overview

Kazuhisa Sekimizu is a researcher affiliated with the University of Tokyo in Japan. Their research contributions span several intersecting fields, including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine.

Their work covers multiple subfields, such as Molecular Biology, Immunology, Insect Science, Pharmacology, and Infectious Diseases. The primary topics explored include Invertebrate Immune Response Mechanisms, Biochemical and Structural Characterization, Insect Utilization and Effects, Antimicrobial Peptides and Activities, Microbial Natural Products and Biosynthesis, Genomics and Phylogenetic Studies, and Antimicrobial Resistance in Staphylococcus.

Among their frequently published venues are Drug Discoveries & Therapeutics, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Frontiers in Microbiology, and Scientific Reports.

Frequently collaborating researchers include Hiroshi Hamamoto, Atsushi Miyashita, Suresh Panthee, Atmika Paudel, and Hiroaki Itoh.

Selected recent publications by Kazuhisa Sekimizu highlight a range of research topics and publication venues:

  • Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library, 2020, Nature Communications
  • Complete genome sequence and comparative genomic analysis of Enterococcus faecalis EF-2001, a probiotic bacterium, 2021, Genomics
  • YjbH regulates virulence genes expression and oxidative stress resistance in Staphylococcus aureus, 2021, Virulence
  • Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter, 2020, PLoS Pathogens
  • Large-Scale Screening and Identification of Novel Pathogenic Staphylococcus aureus Genes Using a Silkworm Infection Model, 2020, The Journal of Infectious Diseases

Best Publications

  • Whole genome sequencing of meticillin-resistant Staphylococcus aureus

    Makoto Kuroda;Toshiko Ohta;Ikuo Uchiyama;Tadashi Baba

  • Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli

    Katsutoshi Imamura;Naoto Imamachi;Gen Akizuki;Michiko Kumakura

  • The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase

    Tsutomu Katayama;Tsutomu Katayama;Toshio Kubota;Kenji Kurokawa;Elliott Crooke

  • Pim Kinases Promote Cell Cycle Progression by Phosphorylating and Down-regulating p27Kip1 at the Transcriptional and Posttranscriptional Levels

    Daisuke Morishita;Ryohei Katayama;Kazuhisa Sekimizu;Takashi Tsuruo

  • Silkworm larvae as an animal model of bacterial infection pathogenic to humans

    Chikara Kaito;Nobuyoshi Akimitsu;Haruo Watanabe;Kazuhisa Sekimizu

  • Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

    Hiroshi Hamamoto;Makoto Urai;Makoto Urai;Kenichi Ishii;Jyunichiro Yasukawa

  • Quantitative Evaluation of the Therapeutic Effects of Antibiotics Using Silkworms Infected with Human Pathogenic Microorganisms

    Hiroshi Hamamoto;Kenji Kurokawa;Chikara Kaito;Koushirou Kamura

  • Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coli.

    Kenji Kurokawa;Kenji Kurokawa;Satoshi Nishida;Akiko Emoto;Kazuhisa Sekimizu;Kazuhisa Sekimizu

  • Pleiotropic Roles of Polyglycerolphosphate Synthase of Lipoteichoic Acid in Growth of Staphylococcus aureus Cells

    Yusuke Oku;Kenji Kurokawa;Kenji Kurokawa;Miki Matsuo;Sakuo Yamada;Sakuo Yamada

  • Silkworm pathogenic bacteria infection model for identification of novel virulence genes.

    Chikara Kaito;Kenji Kurokawa;Yasuhiko Matsumoto;Yutaka Terao

  • A nucleotide switch in the Escherichia coli DnaA protein initiates chromosomal replication. Evidence from a mutant DnaA protein defective in regulatory ATP hydrolysis in vitro and in vivo

    Satoshi Nishida;Kazuyuki Fujimitsu;Kazuhisa Sekimizu;Tadahiro Ohmura

  • Antimicrobial action mechanism of flavonoids from Dorstenia species.

    Jean Paul Dzoyem;Hiroshi Hamamoto;Barthelemy Ngameni;Bonaventure Tchaleu Ngadjui

  • Silkworm as a model animal to evaluate drug candidate toxicity and metabolism

    Hiroshi Hamamoto;Akiko Tonoike;Kazuya Narushima;Ryo Horie

  • DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication.

    Takuma Ishida;Nobuyoshi Akimitsu;Tamami Kashioka;Masakazu Hatano

  • Colony Spreading in Staphylococcus aureus

    Chikara Kaito;Kazuhisa Sekimizu

  • Transcription and Translation Products of the Cytolysin Gene psm-mec on the Mobile Genetic Element SCCmec Regulate Staphylococcus aureus Virulence

    Chikara Kaito;Yuki Saito;Gentaro Nagano;Mariko Ikuo

  • The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2.

    Kenji Kurokawa;Hanna Lee;Hanna Lee;Kyung-Baeg Roh;Miwako Asanuma

  • A role of the Duffy antigen for the maintenance of plasma chemokine concentrations

    Nobuko Fukuma;Nobuyoshi Akimitsu;Hiroshi Hamamoto;Hiroyuki Kusuhara

  • Influence of Cluster Formation of Acidic Phospholipids on Decrease in the Affinity for ATP of DnaA Protein

    Tohru Mizushima;Yuichi Ishikawa;Eishi Obana;Masakazu Hase

  • Characterization of the Staphylococcus aureus mprF gene, involved in lysinylation of phosphatidylglycerol.

    Yusuke Oku;Kenji Kurokawa;Norikazu Ichihashi;Kazuhisa Sekimizu

Frequent Co-Authors

Shunji Natori
Shunji Natori University of Tokyo
Tohru Mizushima
Tohru Mizushima Keio University
Tsutomu Katayama
Tsutomu Katayama Kyushu University
Yoshinobu Nakanishi
Yoshinobu Nakanishi Kanazawa University
Masayuki Inoue
Masayuki Inoue University of Tokyo
Masami Horikoshi
Masami Horikoshi University of Tokyo
Takeo Kubo
Takeo Kubo University of Tokyo
Bok Luel Lee
Bok Luel Lee Pusan National University
Keiichi Hiramatsu
Keiichi Hiramatsu Juntendo University
Yutaka Suzuki
Yutaka Suzuki University of Tokyo

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