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Kirsten Skarstad

Kirsten Skarstad

D-Index & Metrics

Genetics

D-Index
49
Citations
7408
World Ranking
4004
National Ranking
14

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Kirsten Skarstad is affiliated with Oslo University Hospital in Norway. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology, genetics, and molecular medicine.

Their scientific contributions include studies on DNA repair mechanisms, bacterial genetics and biotechnology, and antibiotic resistance in bacteria. Additional research topics cover DNA and nucleic acid chemistry, cancer therapeutics and mechanisms, as well as environmental impacts related to pharmaceuticals and antibiotics.

Among recent papers authored or coauthored by Skarstad are:

  • Antimicrobial resistance: A challenge awaiting the post-COVID-19 era (2021) published in International Journal of Infectious Diseases
  • Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli (2021) published in Scientific Reports
  • Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis (2020) published in Nucleic Acids Research
  • Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability (2020) published in Scientific Reports
  • A DnaA-dependent riboswitch for transcription attenuation of the his operon (2023) published in mLife

Frequent coauthors in their research activities include Magnar Bjørås, James A. Booth, Emily Helgesen, Synnøve Brandt Ræder, and A. Tekle.

Skarstad's work has appeared multiple times in specific publication venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory) with 5 publications
  • Scientific Reports with 3 publications
  • Nucleic Acids Research with 2 publications
  • International Journal of Infectious Diseases with 1 publication
  • mLife with 1 publication

The scientist's research is situated largely within the fields of molecular biology and genetics, extending to applied microbiology and biotechnology as well as issues of pollution. Their focus on DNA repair and bacterial genetics contributes to understanding antibiotic resistance mechanisms and bacterial mutagenesis processes.

Kirsten Skarstad holds membership in the European Molecular Biology Organization (EMBO), reflecting recognition within the molecular biology research community.

Best Publications

  • Timing of initiation of chromosome replication in individual Escherichia coli cells.

    Kirsten Skarstad;Erik Boye;H. B. Steen

  • The DnaA protein determines the initiation mass of Escherichia coli K-12.

    Anders Løbner-Olesen;Kirsten Skarstad;Flemming G. Hansen;Kaspar von Meyenburg

  • E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration

    Steven Slater;Sture Wold;Min Lu;Erik Boye

  • Regulating DNA Replication in Bacteria

    Kirsten Skarstad;Tsutomu Katayama

  • Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins

    Erik Boye;Trond Stokke;Nancy Kleckner;Kirsten Skarstad

  • The initiator protein DnaA: evolution, properties and function

    Kirsten Skarstad;Erik Boye

  • Limiting DNA replication to once and only once

    Erik Boye;Anders Løbner-Olesen;Kirsten Skarstad

  • Strand separation required for initiation of replication at the chromosomal origin of E.coli is facilitated by a distant RNA-DNA hybrid

    Kirsten Skarstad;Tania A. Baker;Arthur Kornberg

  • Cell cycle parameters of slowly growing Escherichia coli B/r studied by flow cytometry.

    K Skarstad;H B Steen;E Boye

  • Escherichia coli DNA distributions measured by flow cytometry and compared with theoretical computer simulations

    K Skarstad;H B Steen;E Boye

  • The initiation mass for DNA replication in Escherichia coli K-12 is dependent on growth rate.

    S Wold;K Skarstad;H B Steen;T Stokke

  • A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli.

    Stéphanie Gon;Stéphanie Gon;Johanna E Camara;Hege K Klungsøyr;Elliott Crooke

  • Applications of flow cytometry on bacteria: Cell cycle kinetics, drug effects, and quantitation of antibody binding

    Harald B. Steen;Erik Boye;Kirsten Skarstad;Barry Bloom

  • Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli

    Solveig Fossum;Elliott Crooke;Kirsten Skarstad

  • A novel binding protein of the origin of the Escherichia coli chromosome.

    Kirsten Skarstad;Beat Thöny;Deog Su Hwang;Arthur Kornberg

  • Flow Cytometry of Bacteria: a Promising Tool in Experimental and Clinical Microbiology

    Erik Boye;Harald B. Steen;Kirsten Skarstad

  • The Escherichia coli SeqA protein.

    Torsten Waldminghaus;Kirsten Skarstad

  • Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism.

    Felipe Molina;Kirsten Skarstad

  • Coordination of chromosome replication initiation in Escherichia coli: effects of different dnaA alleles.

    K Skarstad;K von Meyenburg;F G Hansen;E Boye

  • Degradation of individual chromosomes in recA mutants of Escherichia coli.

    Kirsten Skarstad;Erik Boye

Frequent Co-Authors

Anders Løbner-Olesen
Anders Løbner-Olesen University of Copenhagen
Magnar Bjørås
Magnar Bjørås Norwegian University of Science and Technology
Walter Messer
Walter Messer Max Planck Society
Harald Steen
Harald Steen Oslo University Hospital
Grzegorz Węgrzyn
Grzegorz Węgrzyn University of Gdańsk
Beat Thöny
Beat Thöny University of Zurich
Arthur Kornberg
Arthur Kornberg Stanford University
Nancy Kleckner
Nancy Kleckner Harvard University
Lumir Krejci
Lumir Krejci Masaryk University
Hanno Steen
Hanno Steen Boston Children's Hospital

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