World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
90
Citations
29161
World Ranking
2066
National Ranking
755

Biology and Biochemistry

D-Index
93
Citations
31227
World Ranking
2109
National Ranking
1145

Best Publications

  • Role of quinones in toxicology.

    Judy L. Bolton;Michael A. Trush;Trevor M. Penning;Glenn Dryhurst

  • Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

    Michael Stanbrough;Glenn J. Bubley;Kenneth Ross;Todd R. Golub

  • Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Lauren E. Tebay;Holly Robertson;Stephen T. Durant;Steven R. Vitale

  • Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.

    Trevor M. Penning;Michael E. Burczynski;Joseph M. Jez;Chien-Fu Hung

  • Comparative anatomy of the aldo-keto reductase superfamily.

    Joseph M. Jez;Melanie J. Bennett;Brian P. Schlegel;Mitchell Lewis

  • Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps.

    Mihir S. Date;Devin O’Brien;Danielle J. Botelho;Terry W. Schultz

  • Molecular Endocrinology of Hydroxysteroid Dehydrogenases

    Trevor M. Penning

  • Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones.

    Trevor M. Penning;Michael E. Burczynski;Chien Fu Hung;Kirsten D. McCoull

  • The aldo-keto reductases (AKRs): Overview

    Trevor M. Penning

  • The biochemical basis for increased Testosterone production in theca cells propagated from patients with polycystic ovary syndrome

    Velen L. Nelson;Ke-nan Qin;Robert L. Rosenfield;Jennifer R. Wood

  • The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

    Bengt Persson;Yvonne Kallberg;Yvonne Kallberg;James E. Bray;Elspeth Bruford

  • A new nomenclature for the aldo-keto reductase superfamily

    J M Jez;T G Flynn;T M Penning

  • Aldo-Keto Reductases and Bioactivation/Detoxication

    Yi Jin;Trevor M. Penning

  • Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds

    A.Kenneth MacLeod;Michael McMahon;Simon M. Plummer;Larry G. Higgins

  • The aldo-keto reductase superfamily homepage.

    David Hyndman;David R Bauman;Vladi V Heredia;Trevor M Penning

  • Human Cytosolic 3α-Hydroxysteroid Dehydrogenases of the Aldo-keto Reductase Superfamily Display Significant 3β-Hydroxysteroid Dehydrogenase Activity IMPLICATIONS FOR STEROID HORMONE METABOLISM AND ACTION

    Stephan Steckelbroeck;Yi Jin;Sridhar Gopishetty;Busola Oyesanmi

  • Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

    Karen E. Knudsen;Trevor M. Penning

  • Human Aldo-Keto Reductases: Function, Gene Regulation, and Single Nucleotide Polymorphisms

    Trevor M. Penning;Jason E. Drury

  • Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents.

    Lawrence M. Szewczuk;Luca Forti;Lucia A. Stivala;Trevor M. Penning

  • Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.

    Nisha T. Palackal;Seon Hwa Lee;Ronald G. Harvey;Ian A. Blair

Frequent Co-Authors

Ian A. Blair
Ian A. Blair University of Pennsylvania
Ronald G. Harvey
Ronald G. Harvey University of Chicago
Joseph M. Jez
Joseph M. Jez Washington University in St. Louis
Wolfgang Dekant
Wolfgang Dekant University of Würzburg
Steven P. Balk
Steven P. Balk Beth Israel Deaconess Medical Center
Thomas E. Smithgall
Thomas E. Smithgall University of Pittsburgh
Peter S. Nelson
Peter S. Nelson Fred Hutchinson Cancer Research Center
Mary-Ellen Taplin
Mary-Ellen Taplin Harvard University
David W. Christianson
David W. Christianson University of Pennsylvania
Jeffrey Field
Jeffrey Field University of Pennsylvania

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