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Albena T. Dinkova-Kostova

Albena T. Dinkova-Kostova

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Biology and Biochemistry
UK
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
54382
World Ranking
2378
National Ranking
163

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Albena T. Dinkova-Kostova is affiliated with the University of Dundee in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Organic Chemistry, Immunology, Pharmacology, and Physiology subfields.

Their main research topics include:

  • Genomics, phytochemicals, and oxidative stress
  • Glutathione Transferases and Polymorphisms
  • Synthesis and Biological Evaluation
  • Free Radicals and Antioxidants
  • Coenzyme Q10 studies and effects
  • Heme Oxygenase-1 and Carbon Monoxide
  • IL-33, ST2, and ILC Pathways

Albena T. Dinkova-Kostova has contributed to several recent papers, including:

  • Advances and challenges in therapeutic targeting of NRF2, 2023, Trends in Pharmacological Sciences
  • Natural products in drug discovery: advances and opportunities, 2021, Nature Reviews Drug Discovery
  • Oxidative Stress in Cancer, 2020, Cancer Cell
  • Can Activation of NRF2 Be a Strategy against COVID-19?, 2020, Trends in Pharmacological Sciences
  • Molecular basis for the disruption of Keap1-Nrf2 interaction via Hinge & Latch mechanism, 2021, Communications Biology

Frequent co-authors collaborating with this researcher include Sharadha Dayalan Naidu, Maureen Higgins, Elena V. Knatko, Tadashi Honda, and Laureano de la Vega.

Their publications have appeared predominantly in the following venues:

  • Free Radical Biology and Medicine
  • Redox Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Antioxidants

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Natural products in drug discovery: advances and opportunities.

    Atanas G Atanasov;Sergey B Zotchev;Verena M Dirsch

  • Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

    Albena T. Dinkova-Kostova;W. David Holtzclaw;Robert N. Cole;Ken Itoh

  • The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

    John D. Hayes;Albena T. Dinkova-Kostova

  • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

    Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya

  • Oxidative Stress in Cancer.

    John D. Hayes;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Kenneth D. Tew

  • Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.

    Nobunao Wakabayashi;Albena T. Dinkova-Kostova;W. David Holtzclaw;Moon Il Kang

  • The cytoprotective role of the Keap1–Nrf2 pathway

    Liam Baird;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova

  • Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

    Antonio Cuadrado;Ana I. Rojo;Geoffrey Wells;John D. Hayes

  • Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Lauren E. Tebay;Holly Robertson;Stephen T. Durant;Steven R. Vitale

  • The emerging role of Nrf2 in mitochondrial function.

    Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Andrey Y. Abramov

  • Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

    Vittorio Calabrese;Carolin Cornelius;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Edward J. Calabrese

  • NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

    Albena T. Dinkova-Kostova;Paul Talalay

  • Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

    Albena T. Dinkova-Kostova;Michael A. Massiah;Richard E. Bozak;Ronald J. Hicks

  • Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress

    Albena T. Dinkova-Kostova;Karen T. Liby;Katherine K. Stephenson;W. David Holtzclaw

  • Direct and indirect antioxidant properties of inducers of cytoprotective proteins.

    Albena T. Dinkova-Kostova;Paul Talalay

  • Glucosinolates and isothiocyanates in health and disease

    Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Rumen V. Kostov

  • Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

    John D. Hayes;Michael McMahon;Sudhir Chowdhry;Albena T. Dinkova-Kostova

  • Nrf2 regulates ROS production by mitochondria and NADPH oxidase

    Stjepana Kovac;Plamena R. Angelova;Kira M. Holmström;Ying Zhang

  • Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans

    Lingxiang Ye;Albena T Dinkova-Kostova;Kristina L Wade;Yuesheng Zhang

Frequent Co-Authors

Paul Talalay
Paul Talalay Johns Hopkins University School of Medicine
Tadashi Honda
Tadashi Honda Stony Brook University
Jed W. Fahey
Jed W. Fahey Johns Hopkins University
John D. Hayes
John D. Hayes University of Dundee
Andrey Y. Abramov
Andrey Y. Abramov University College London
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Vittorio Calabrese
Vittorio Calabrese University of Catania
Thomas W. Kensler
Thomas W. Kensler Johns Hopkins University
Philip A. Cole
Philip A. Cole Brigham and Women's Hospital
Michael L. J. Ashford
Michael L. J. Ashford University of Dundee

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