Albena T. Dinkova-Kostova mainly investigates Biochemistry, KEAP1, Transcription factor, Cell biology and Sulforaphane. Her work on Biochemistry deals in particular with Antioxidant, Enzyme inducer, Oxidative stress, Enzyme and Cysteine. Her KEAP1 research is multidisciplinary, relying on both Oxidoreductase, Cell, Ubiquitin ligase and Inducer.
The various areas that Albena T. Dinkova-Kostova examines in her Transcription factor study include Ubiquitin and Signal transducing adaptor protein. Her Cell biology research is multidisciplinary, incorporating perspectives in Apoptosis, Endogeny, Transcriptional regulation and Angiogenesis. Her work is dedicated to discovering how Sulforaphane, Isothiocyanate are connected with Pharmacology, Broccoli sprouts and Disease and other disciplines.
Her main research concerns Biochemistry, KEAP1, Transcription factor, Oxidative stress and Cell biology. Her work carried out in the field of KEAP1 brings together such families of science as Cancer research, Ubiquitin, Cytoprotection, Oxidative phosphorylation and Cysteine. Her study in Transcription factor is interdisciplinary in nature, drawing from both Ubiquitin ligase and HSF1.
Her study looks at the intersection of Oxidative stress and topics like Inflammation with Biomarker. Her research investigates the link between Cell biology and topics such as Downregulation and upregulation that cross with problems in Carcinogenesis. Her Sulforaphane research focuses on Pharmacology and how it connects with Broccoli sprouts and Isothiocyanate.
Her scientific interests lie mostly in Cancer research, Oxidative stress, Inflammation, Transcription factor and KEAP1. Albena T. Dinkova-Kostova combines subjects such as Cell, Cancer cell, Cancer, Carcinogenesis and Kinase with her study of Cancer research. The concepts of her Oxidative stress study are interwoven with issues in DNA damage, Toxicity and In vivo.
Her biological study spans a wide range of topics, including Swietenine, HMOX1, Biomarker, Arsenic toxicity and Pharmacology. Her studies deal with areas such as HEK 293 cells, Transcription and Cell biology as well as Transcription factor. Her research in KEAP1 intersects with topics in Cytoprotection, Downregulation and upregulation and Cysteine.
Albena T. Dinkova-Kostova mainly focuses on Inflammation, Oxidative stress, Cytoprotection, Transcription factor and KEAP1. Her Inflammation study integrates concerns from other disciplines, such as Heat shock protein and Sulforaphane. Her Oxidative stress research is multidisciplinary, incorporating perspectives in Immune dysregulation, Immunology, Peripheral blood mononuclear cell, Hsp70 and Biomarker.
Her studies in Transcription factor integrate themes in fields like AMPK, Ubiquitin ligase and Cell biology. Her Cell biology study combines topics from a wide range of disciplines, such as Carcinogenesis, Cancer cell, HSF1 and Pentose phosphate pathway. She has included themes like Cancer research and Bardoxolone methyl in her KEAP1 study.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
Albena T. Dinkova-Kostova;W. David Holtzclaw;Robert N. Cole;Ken Itoh.
Proceedings of the National Academy of Sciences of the United States of America (2002)
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
John D. Hayes;Albena T. Dinkova-Kostova.
Trends in Biochemical Sciences (2014)
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Nobunao Wakabayashi;Albena T. Dinkova-Kostova;W. David Holtzclaw;Moon Il Kang.
Proceedings of the National Academy of Sciences of the United States of America (2004)
The cytoprotective role of the Keap1–Nrf2 pathway
Liam Baird;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova;Albena T. Dinkova-Kostova.
Archives of Toxicology (2011)
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya.
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
Albena T. Dinkova-Kostova;Michael A. Massiah;Richard E. Bozak;Ronald J. Hicks.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
Albena T. Dinkova-Kostova;Karen T. Liby;Katherine K. Stephenson;W. David Holtzclaw.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
Lauren E. Tebay;Holly Robertson;Stephen T. Durant;Steven R. Vitale.
Free Radical Biology and Medicine (2015)
NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
Albena T. Dinkova-Kostova;Paul Talalay.
Archives of Biochemistry and Biophysics (2010)
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