D-Index & Metrics Best Publications
Biology and Biochemistry
Spain
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 74 Citations 26,521 210 World Ranking 3446 National Ranking 32

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

Antonio Cuadrado mostly deals with Transcription factor, Biochemistry, Cell biology, PI3K/AKT/mTOR pathway and Microglia. His research investigates the connection between Transcription factor and topics such as Ubiquitin ligase that intersect with problems in LY294002 and Scaffold protein. His study in the field of GSK-3, Signal transduction, Oxidative stress and Malondialdehyde also crosses realms of Choline kinase.

His Cell biology research is multidisciplinary, incorporating elements of Cancer research and Gene expression. Antonio Cuadrado has included themes like Molecular biology, Protein kinase B and Kinase in his PI3K/AKT/mTOR pathway study. He combines subjects such as Neuroinflammation, Neuroprotection, In vivo and Sulforaphane with his study of Microglia.

His most cited work include:

  • Regulation of Heme Oxygenase-1 Expression through the Phosphatidylinositol 3-Kinase/Akt Pathway and the Nrf2 Transcription Factor in Response to the Antioxidant Phytochemical Carnosol (600 citations)
  • SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner. (450 citations)
  • The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation (347 citations)

What are the main themes of his work throughout his whole career to date?

Antonio Cuadrado mainly focuses on Cell biology, Transcription factor, Oxidative stress, Internal medicine and Molecular biology. His Cell biology research incorporates themes from Autophagy, Apoptosis and Biochemistry. He has researched Transcription factor in several fields, including Proteostasis and Ubiquitin ligase.

His study in Oxidative stress is interdisciplinary in nature, drawing from both Reactive oxygen species, Neuroprotection, Pharmacology and Neuroinflammation, Disease. His studies in Internal medicine integrate themes in fields like Gastroenterology and Endocrinology. The Molecular biology study combines topics in areas such as Protein kinase C, Kinase and Transfection.

He most often published in these fields:

  • Cell biology (31.89%)
  • Transcription factor (22.70%)
  • Oxidative stress (18.38%)

What were the highlights of his more recent work (between 2017-2021)?

  • Transcription factor (22.70%)
  • Cell biology (31.89%)
  • Disease (7.03%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Transcription factor, Cell biology, Disease, Internal medicine and Oxidative stress. His work carried out in the field of Transcription factor brings together such families of science as Proteostasis and Quinone. The various areas that Antonio Cuadrado examines in his Cell biology study include Autophagy and Neuroprotection.

His studies deal with areas such as Reactive oxygen species, Drug development, Neuroscience and Drug discovery as well as Disease. The Internal medicine study which covers Gastroenterology that intersects with Vascular disease. His Oxidative stress research includes elements of Cancer, Antioxidant and Mechanism of action.

Between 2017 and 2021, his most popular works were:

  • Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases (291 citations)
  • Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach (198 citations)
  • Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development (122 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Antonio Cuadrado mainly investigates Cell biology, Transcription factor, Neuroinflammation, Inflammation and Bioinformatics. His work investigates the relationship between Cell biology and topics such as Autophagy that intersect with problems in Signalling and Multicellular organism. Much of his study explores Transcription factor relationship to Proteostasis.

The concepts of his Neuroinflammation study are interwoven with issues in Neurodegeneration and Tauopathy. His Inflammation research is multidisciplinary, incorporating perspectives in Cytoprotection and KEAP1. His Bioinformatics study combines topics from a wide range of disciplines, such as Oxidative stress and Cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Autophagy (2021)

8964 Citations

Regulation of Heme Oxygenase-1 Expression through the Phosphatidylinositol 3-Kinase/Akt Pathway and the Nrf2 Transcription Factor in Response to the Antioxidant Phytochemical Carnosol

Daniel Martin;Ana I. Rojo;Marta Salinas;Raquel Diaz;Raquel Diaz;Raquel Diaz.
Journal of Biological Chemistry (2004)

920 Citations

Clinical Relevance of Biomarkers of Oxidative Stress

Jeroen Frijhoff;Paul Graham Winyard;Neven Zarkovic;Sean Ss Davies.
Antioxidants & Redox Signaling (2015)

622 Citations

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Antonio Cuadrado;Ana I. Rojo;Geoffrey Wells;John D. Hayes.
Nature Reviews Drug Discovery (2019)

579 Citations

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

Patricia Rada;Ana I. Rojo;Sudhir Chowdhry;Michael McMahon.
Molecular and Cellular Biology (2011)

549 Citations

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

Sudhir Chowdhry;Yiguo Zhang;Michael McMahon;Calum Sutherland.
Oncogene (2013)

512 Citations

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

Nadia G. Innamorato;Ana I. Rojo;Ángel Juan García-Yagüe;Masayuki Yamamoto.
Journal of Immunology (2008)

490 Citations

Glycogen Synthase Kinase-3β Inhibits the Xenobiotic and Antioxidant Cell Response by Direct Phosphorylation and Nuclear Exclusion of the Transcription Factor Nrf2

María Salazar;Ana I. Rojo;Diego Velasco;Rosa María de Sagarra.
Journal of Biological Chemistry (2006)

451 Citations

Activation of Akt/Protein Kinase B by G Protein-coupled Receptors A ROLE FOR α AND βγ SUBUNITS OF HETEROTRIMERIC G PROTEINS ACTING THROUGH PHOSPHATIDYLINOSITOL-3-OH KINASEγ

Cristina Murga;Luciana Laguinge;Reinhard Wetzker;Antonio Cuadrado.
Journal of Biological Chemistry (1998)

433 Citations

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis

Antonio Cuadrado.
Molecular and Cellular Biology (2012)

372 Citations

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