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Harald H.H.W. Schmidt

Harald H.H.W. Schmidt

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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
100
Citations
37865
World Ranking
1513
National Ranking
26

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Harald H.H.W. Schmidt is affiliated with Maastricht University in the Netherlands. Their research spans multiple disciplines within the broader fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Notably, they have contributed extensively to Molecular Biology, Physiology, Neurology, Computational Theory and Mathematics, and Immunology.

The scientist's work covers a range of topics including:

  • Bioinformatics and Genomic Networks
  • Nitric Oxide and Endothelin Effects
  • Computational Drug Discovery Methods
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Gene expression and cancer classification
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Health, Environment, Cognitive Aging

Harald H.H.W. Schmidt has collaborated frequently with several researchers. These co-authors include Jan Baumbach, Cristian Nogales, Ana I. Casas, Mahmoud H. Elbatreek, and Markus List.

The scientist has published in a variety of journals and venues, with frequent contributions to:

  • Network and Systems Medicine
  • IUPHAR/BPS Guide to Pharmacology CITE
  • Scientific Reports
  • Drug repurposing
  • UNC Libraries

Among recent papers, notable examples include:

  • Network pharmacology: curing causal mechanisms instead of treating symptoms, 2021, Trends in Pharmacological Sciences
  • Molecular networks in Network Medicine: Development and applications, 2020, WIREs Systems Biology and Medicine
  • Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification, 2020, Circulation Research
  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors, 2021, British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors, 2023, British Journal of Pharmacology

Additionally, Harald H.H.W. Schmidt has contributed to academic book publications. One such work is titled Reactive Oxygen Species, published in 2021 by Springer Science+Business Media.

Best Publications

  • NO at work

    Harald H.H.W. Schmidt;Ulrich Walter

  • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

    Jennifer S. Pollock;Ulrich Forstermann;Jane A. Mitchell;Timothy D. Warner

  • Isoforms of nitric oxide synthase Characterization and purification from different cell types

    Ulrich Förstermann;Haral H.H.W. Schmidt;Jennifer S. Pollock;Hong Sheng

  • The nitric oxide and cGMP signal transduction system: regulation and mechanism of action

    Harald H.H.W. Schmidt;Suzanne M. Lohmann;Ulrich Walter

  • Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction.

    H. H. H. W. Schmidt;G. D. Gagne;M. Nakane;J. S. Pollock

  • NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

    Oleg V. Evgenov;Pál Pacher;Peter M. Schmidt;György Haskó

  • Clinical Relevance of Biomarkers of Oxidative Stress

    Jeroen Frijhoff;Paul Graham Winyard;Neven Zarkovic;Sean Ss Davies

  • Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

    Sabine Heumüller;Sven Wind;Eduardo Barbosa-Sicard;Harald H.H.W. Schmidt

  • Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells

    Ulrich Forstermann;Jennifer S. Pollock;Harald H. H. Schmidt;Michael Heller

  • Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle

    Masaki Nakane;Harald H.H.W. Schmidt;Jennifer S. Pollock;Ulrich Förstermann

  • Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase

    Rashmi K. Ambasta;Pravir Kumar;Kathy K. Griendling;Harald H.H.W. Schmidt

  • Nitric oxide synthase in macula densa regulates glomerular capillary pressure

    Christopher S. Wilcox;William J. Welch;Ferid Murad;Steven S. Gross

  • Arginine is a physiological precursor of endothelium-derived nitric oxide

    Harald H.H.W. Schmidt;Heinz Nau;Werner Wittfoht;Jörg Gerlach

  • Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

    Sebastian Altenhöfer;Kim A. Radermacher;Pamela W.M. Kleikers;Kirstin Wingler

  • Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

    Antonio Cuadrado;Gina Manda;Ahmed Hassan;María José Alcaraz

  • Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides

    Harald H. H. W. Schmidt;Timothy D. Warner;Kunio Ishii;Hong Sheng

  • NOX1 OVEREXPRESSION POTENTIATES ANGIOTENSIN II-INDUCED HYPERTENSION AND VASCULAR SMOOTH MUSCLE HYPERTROPHY IN TRANSGENIC MICE

    Anna Dikalova;Roza Clempus;Bernard Lassègue;Guangjie Cheng

  • Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

    Johannes-Peter Stasch;Peter M. Schmidt;Pavel I. Nedvetsky;Tatiana Y. Nedvetskaya

  • No .NO from NO synthase.

    Harald H. H. W. Schmidt;Heinrich Hofmann;Ursula Schindler;Zhanna S. Shutenko

  • Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant. Commentary

    Rhian M. Touyz;Sabine Heumüller;Sven Wind;Eduardo Barbosa-Sicard

Frequent Co-Authors

Jan Baumbach
Jan Baumbach Universität Hamburg
Ulrich Förstermann
Ulrich Förstermann Johannes Gutenberg University of Mainz
Wolfgang Pfleiderer
Wolfgang Pfleiderer University of Konstanz
Christoph Kleinschnitz
Christoph Kleinschnitz University of Duisburg-Essen
Mark E. Cooper
Mark E. Cooper Monash University
Jennifer S. Pollock
Jennifer S. Pollock University of Alabama at Birmingham
Ferid Murad
Ferid Murad The University of Texas Health Science Center at Houston
Rhian M. Touyz
Rhian M. Touyz McGill University Health Centre
Richard J. Weinberg
Richard J. Weinberg University of North Carolina at Chapel Hill
Antonio Cuadrado
Antonio Cuadrado Autonomous University of Madrid

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