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Christoph Kleinschnitz

Christoph Kleinschnitz

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
22797
World Ranking
4306
National Ranking
320

Overview

Christoph Kleinschnitz is affiliated with the University of Duisburg-Essen in Germany, specializing in medical research with a focus on neurology. Their body of work primarily revolves around neurological disorders, neurogenetics, and neuroinflammation, encompassing both clinical and molecular approaches.

The scientist has contributed to 571 publications within the broader field of Medicine, with significant specialization in the following subfields:

  • Neurology
  • Genetics
  • Molecular Biology
  • Pathology and Forensic Medicine
  • Epidemiology

The main research topics addressed by Kleinschnitz include:

  • Multiple Sclerosis Research Studies
  • Neurogenetic and Muscular Disorders Research
  • Glioma Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Peripheral Neuropathies and Disorders
  • Long-Term Effects of COVID-19

Kleinschnitz has published numerous papers in prominent journals. Some of their recent works include:

  • "Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study," published in 2020 in The Lancet Neurology
  • "Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice," published in 2021 in Basic Research in Cardiology
  • "Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid," published in 2020 in Immunity
  • "Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper)," published in 2021 in Therapeutic Advances in Neurological Disorders
  • "Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients," published in 2022 in Journal of Neuroinflammation

Frequent co-authors collaborating with Kleinschnitz include:

  • Tim Hagenacker
  • Ulrich Sure
  • Martin Glas
  • Cornelius Deuschl
  • Sied Kebir

Regarding publication venues, Kleinschnitz often publishes in the following journals:

  • Neuro-Oncology
  • Therapeutic Advances in Neurological Disorders
  • Neurological Research and Practice
  • European Journal of Neurology
  • Journal of Neurology

Best Publications

  • Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

    Sven Jarius;Klemens Ruprecht;Brigitte Wildemann;Tania Kuempfel

  • Animal models of ischemic stroke and their application in clinical research.

    Felix Fluri;Michael K Schuhmann;Christoph Kleinschnitz

  • Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

    Christoph Kleinschnitz;Guido Stoll;Martin Bendszus;Kai Schuh

  • Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

    Christoph Kleinschnitz;Henrike Grund;Kirstin Wingler;Melanie Elise Armitage

  • Targeting Platelets in Acute Experimental Stroke Impact of Glycoprotein Ib, VI, and IIb/IIIa Blockade on Infarct Size, Functional Outcome, and Intracranial Bleeding

    Christoph Kleinschnitz;Miroslava Pozgajova;Mirko Pham;Martin Bendszus

  • Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

    David Schafflick;Chenling A. Xu;Maike Hartlehnert;Michael Cole

  • Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

    Christoph Kleinschnitz;Nicholas Schwab;Peter Kraft;Ina Hagedorn

  • Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

    Christoph Kleinschnitz;Peter Kraft;Angela Dreykluft;Ina Hagedorn

  • The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

    Menno V. Huisman;Kenneth J. Rothman;Miney Paquette;Christine Teutsch

  • Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

    Attila Braun;Bernhard Nieswandt;Dávid Varga-Szabó

  • STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death

    Alejandro Berna-Erro;Attila Braun;Robert Kraft;Christoph Kleinschnitz

  • Neuroprotection for ischaemic stroke: Translation from the bench to the bedside

    Brad A. Sutherland;Jens Minnerup;Joyce S. Balami;Francesco Arba

  • Thromboinflammation in Stroke Brain Damage.

    Simon F. De Meyer;Frederik Denorme;Friederike Langhauser;Eva Geuss

  • The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

    David Varga-Szabo;Attila Braun;Christoph Kleinschnitz;Markus Bender

  • Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

    Guido Stoll;Christoph Kleinschnitz;Bernhard Nieswandt;Bernhard Nieswandt

  • Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1.

    Margitta Elvers;David Stegner;Ina Hagedorn;Christoph Kleinschnitz

  • Ischaemic stroke: a thrombo-inflammatory disease?

    Bernhard Nieswandt;Christoph Kleinschnitz;Guido Stoll

  • Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

    Ina Hagedorn;Stefan Schmidbauer;Irina Pleines;Christoph Kleinschnitz

  • Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

    Ingo Kleiter;Anna Gahlen;Nadja Borisow;Katrin Fischer

  • Neuroprotection for Stroke: Current Status and Future Perspectives

    Jens Minnerup;Brad A. Sutherland;Alastair M. Buchan;Christoph Kleinschnitz

Frequent Co-Authors

Sven G. Meuth
Sven G. Meuth University of Münster
Heinz Wiendl
Heinz Wiendl University of Münster
Bernhard Nieswandt
Bernhard Nieswandt University of Würzburg
Peter Kraft
Peter Kraft Harvard University
Michael Forsting
Michael Forsting University of Duisburg-Essen
Dirk M. Hermann
Dirk M. Hermann University of Duisburg-Essen
Martin Bendszus
Martin Bendszus University Hospital Heidelberg
Harald H.H.W. Schmidt
Harald H.H.W. Schmidt Maastricht University
Martin Stangel
Martin Stangel Hannover Medical School
Thomas Budde
Thomas Budde University of Münster

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