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Immunology

D-Index
70
Citations
18433
World Ranking
2407
National Ranking
164

Medicine

D-Index
70
Citations
18582
World Ranking
20086
National Ranking
1047

Overview

Klemens Ruprecht is affiliated with Charité - University Medicine Berlin in Germany, focusing primarily on medical research within the fields of pathology, forensic medicine, and neurology. Their work spans multiple subfields including rheumatology, molecular biology, and immunology, reflecting a broad interdisciplinary approach to medicine.

Their research extensively covers topics related to multiple sclerosis, peripheral neuropathies, and systemic lupus erythematosus. Additional areas of interest include neuroinflammation and neurodegeneration mechanisms, polyomavirus and associated diseases, long-term effects of COVID-19, and ocular diseases such as Behçet's syndrome.

Ruprecht has contributed to a significant number of publications, with key venues for their work including:

  • Neurology
  • Neurology Neuroimmunology & Neuroinflammation
  • Journal of Neurology
  • Journal of Neuroinflammation
  • bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in Ruprecht's research include Friedemann Paul, Judith Bellmann-Strobl, Carolin Otto, Sven Jarius, and Susanna Asseyer, with collaboration counts ranging from 28 to 68 publications.

Among Ruprecht's recent published papers are the following:

  • Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis (2023), Journal of Neurology
  • Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients (2022), Journal of Neuroinflammation
  • Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients (2020), Journal of Neuroinflammation
  • Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management (2023), Journal of Neurology
  • Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors (2020), JCI Insight

Best Publications

  • MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

    Sven Jarius;Klemens Ruprecht;Ingo Kleiter;Nadja Borisow

  • Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

    Sven Jarius;Klemens Ruprecht;Brigitte Wildemann;Tania Kuempfel

  • MOG encephalomyelitis: International recommendations on diagnosis and antibody testing

    S. Jarius;F. Paul;F. Paul;O. Aktas;N. Asgari

  • A blood based 12-miRNA signature of Alzheimer disease patients

    Petra Leidinger;Christina Backes;Stephanie Deutscher;Katja Schmitt

  • MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

    Sven Jarius;Klemens Ruprecht;Ingo Kleiter;Nadja Borisow

  • Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls

    Andreas Keller;Petra Leidinger;Julia Lange;Anne Borries

  • Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.

    Ingo Kleiter;Anna Gahlen;Nadja Borisow;Katrin Fischer

  • Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: results from 211 lumbar punctures.

    S. Jarius;F. Paul;D. Franciotta;K. Ruprecht

  • Toward the blood-borne miRNome of human diseases

    Andreas Keller;Petra Leidinger;Andrea Bauer;Abdou Elsharawy

  • A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus

    Nelly Scuda;Jörg Hofmann;Sébastien Calvignac-Spencer;Klemens Ruprecht

  • Evaluation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich, glioma-inactivated 1 antibodies

    Carsten Finke;Harald Prüss;Josephine Heine;Sigrid Reuter

  • MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

    Florence Pache;Hanna Zimmermann;Janine Mikolajczak;Sophie Schumacher

  • MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.

    Sven Jarius;Ingo Kleiter;Klemens Ruprecht;Nasrin Asgari

  • Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis

    Tim Sinnecker;Jan Dörr;Caspar F. Pfueller;Lutz Harms

  • Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease

    Hervé Perron;Raphaëlle Germi;Corinne Bernard;Marta Garcia-Montojo

  • Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

    Ingo Kleiter;Anna Gahlen;Nadja Borisow;Katrin Fischer

  • Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

    Sven Jarius;Diego Franciotta;Friedemann Paul;Klemens Ruprecht

  • Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions.

    Hervé Perron;Françoise Lazarini;Klemens Ruprecht;Christine Péchoux-Longin

  • Plasma exchange for severe optic neuritis: treatment of 10 patients.

    K. Ruprecht;E. Klinker;T. Dintelmann;P. Rieckmann

  • Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma

    Dirk Vordermark;Oliver Kölbl;Klemens Ruprecht;Giles H Vince

  • Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis

    Unknown

  • Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination.

    Patrick Peschl;Kathrin Schanda;Bleranda Zeka;Katherine Given

  • Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

    Sven Jarius;Sven Jarius;Jette Frederikson;Patrick Waters;Friedemann Paul

  • Bortezomib for treatment of therapy-refractory anti-NMDA receptor encephalitis.

    Franziska Scheibe;Harald Prüss;Annerose M. Mengel;Siegfried Kohler

  • Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis.

    Klemens Ruprecht;Karola Obojes;Verena Wengel;Felix Gronen

  • Neuromyelitis optica spectrum disorders in patients with myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature.

    S Jarius;F Paul;F Paul;D Franciotta;J de Seze

  • MOG-Enzephalomyelitis: Internationale Empfehlungen zu Diagnose und Antikörpertestung [MOG encephalomyelitis: international recommendations on diagnosis and antibody testing]

    S. Jarius;F. Paul;O. Aktas;N. Asgari

Frequent Co-Authors

Friedemann Paul
Friedemann Paul Charité - University Medicine Berlin
Brigitte Wildemann
Brigitte Wildemann University Hospital Heidelberg
Orhan Aktas
Orhan Aktas Heinrich Heine University Düsseldorf
Carsten Finke
Carsten Finke Charité - University Medicine Berlin
Markus Reindl
Markus Reindl Innsbruck Medical University
Diego Franciotta
Diego Franciotta University of Pavia
Eckart Meese
Eckart Meese Saarland University
Andreas Keller
Andreas Keller Saarland University
Michael J. Levy
Michael J. Levy Harvard Medical School
Hayrettin Tumani
Hayrettin Tumani University of Ulm

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