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Medicine

D-Index
83
Citations
23301
World Ranking
15695
National Ranking
826

Overview

Dirk M. Hermann is affiliated with the University of Duisburg-Essen in Germany. Their research primarily focuses on neuroscience, medicine, and biochemistry, genetics, and molecular biology. The scientist has also contributed extensively to subfields such as neurology, molecular biology, cellular and molecular neuroscience, immunology, and epidemiology.

Their work concentrates on several key topics, including:

  • Neuroinflammation and neurodegeneration mechanisms
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Neurological disease mechanisms and treatments
  • Acute ischemic stroke management
  • Barrier structure and function studies
  • Immune cells in cancer

Among the recent papers authored or co-authored by Dirk M. Hermann are:

  • Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles (2021) published in Cytotherapy
  • Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice (2021) published in Basic Research in Cardiology
  • Adipose-derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR-25 (2020) published in Journal of Extracellular Vesicles
  • Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway (2021) published in Cell Death and Disease
  • Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils (2020) published in Stroke

Dirk M. Hermann collaborates frequently with multiple researchers, including:

  • Thorsten R. Doeppner
  • Aurel Popa-Wagner
  • Matthias Gunzer
  • Nina Hagemann
  • Ayan Mohamud Yusuf

The scientist has published works in notable venues such as:

  • Frontiers in Cellular Neuroscience
  • Stroke
  • Brain Behavior and Immunity
  • Experimental Neurology
  • Exploration of Neuroscience

Dirk M. Hermann has contributed to book publications, including a title released by Frontiers Media: Crosstalk between Peripheral and Local Immune Response in the Pathophysiology of Stroke and Neurodegeneration Diseases (2023).

Best Publications

  • Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  • Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

    Thorsten R. Doeppner;Josephine Herz;André Görgens;Jana Schlechter

  • Post-stroke dementia - a comprehensive review

    Milija D. Mijajlović;Aleksandra Pavlović;Michael Brainin;Wolf Dieter Heiss

  • Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms

    Marco Bacigaluppi;Stefano Pluchino;Luca Peruzzotti Jametti;Ertugrul Kilic

  • Effects of electromagnetic radiation of mobile phones on the central nervous system

    K.-A. Hossmann;D.M. Hermann

  • Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation

    Dirk M Hermann;Michael Chopp;Michael Chopp

  • VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena.

    Yaoming Wang;Ertugrul Kilic;Ülkan Kilic;Bruno Weber

  • The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF’s neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia

    Ertugrul Kilic;Ülkan Kilic;Yaoming Wang;Claudio L. Bassetti

  • Sleep-related breathing and sleep-wake disturbances in ischemic stroke

    Dirk M. Hermann;Claudio L. Bassetti

  • Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales.

    Anna-Kristin Ludwig;Anna-Kristin Ludwig;Kyra De Miroschedji;Thorsten R. Doeppner;Thorsten R. Doeppner;Verena Börger

  • Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways

    Ertugrul Kilic;Ülkan Kilic;Jorge Soliz;Claudio L. Bassetti

  • Afferent projections to the rat nuclei raphe magnus, raphe pallidus and reticularis gigantocellularis pars α demonstrated by iontophoretic application of choleratoxin (subunit b)

    Dirk M Hermann;Pierre-Hervé Luppi;Christelle Peyron;Peter Hinckel

  • Evolution of brain infarction after transient focal cerebral ischemia in mice

    Ryuji Hata;Keiichiro Maeda;Dirk Hermann;Günter Mies

  • Dose-dependent effects of endotoxin on human sleep.

    Janet Mullington;Carsten Korth;Dirk M. Hermann;Armin Orth

  • Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.

    Jens Neumann;Monika Riek-Burchardt;Monika Riek-Burchardt;Josephine Herz;Thorsten R. Doeppner

  • Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice.

    Ertugrul Kilic;Gunnar P. H. Dietz;Dirk M. Hermann;Mathias Bähr

  • Implications of vascular endothelial growth factor for postischemic neurovascular remodeling.

    Dirk Matthias Hermann;Anil Zechariah

  • Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways

    Ülkan Kilic;Ertugrul Kilic;Anne Järve;Zeyun Guo

  • Animal Models of Ischemic Stroke. Part Two: Modeling Cerebral Ischemia

    Marco Bacigaluppi;Giancarlo Comi;Dirk M. Hermann

  • Applying extracellular vesicles based therapeutics in clinical trials

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

Frequent Co-Authors

Ertugrul Kilic
Ertugrul Kilic Istanbul Medipol University
Claudio L. Bassetti
Claudio L. Bassetti University of Bern
Mathias Bähr
Mathias Bähr University of Göttingen
Christoph Kleinschnitz
Christoph Kleinschnitz University of Duisburg-Essen
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Bernd Giebel
Bernd Giebel University of Duisburg-Essen
Raimund Erbel
Raimund Erbel University of Duisburg-Essen
Karl-Heinz Jöckel
Karl-Heinz Jöckel University of Duisburg-Essen
Susanne Moebus
Susanne Moebus University of Duisburg-Essen
Stefano Pluchino
Stefano Pluchino University of Cambridge

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