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Immunology

D-Index
73
Citations
19034
World Ranking
2142
National Ranking
148

Overview

Matthias Gunzer is affiliated with the University of Duisburg-Essen in Germany. Their research primarily focuses on immunology and molecular biology within the broader fields of medicine and biochemistry. The scientist's work spans several subfields, including immunology, molecular biology, neurology, epidemiology, and biophysics.

Gunzer has authored multiple papers addressing key topics such as neutrophil biology, immune responses in cancer, neuroinflammation, and advanced microscopy techniques. Their research contributions include the following recent publications:

  • Co-option of Neutrophil Fates by Tissue Environments (2020, Cell)
  • Durable and controlled depletion of neutrophils in mice (2020, Nature Communications)
  • Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice (2021, Basic Research in Cardiology)
  • Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling (2020, Nature Communications)
  • Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils (2020, Stroke)

Frequent co-authors collaborating with Gunzer include Dirk M. Hermann, Nina Hagemann, Jianxu Chen, Ayan Mohamud Yusuf, and Vikramjeet Singh. These partnerships have contributed to a range of studies primarily published in well-known scientific venues.

The most common venues for Gunzer's publications are bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Frontiers in Immunology, and Brain Behavior and Immunity. These outlets reflect the interdisciplinary nature of their research.

The main academic topics in Gunzer's research encompass:

  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune cells in cancer
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune Response and Inflammation
  • Advanced Fluorescence Microscopy Techniques
  • Cell Image Analysis Techniques
  • Immunotherapy and Immune Responses

Best Publications

  • Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation.

    Katia De Filippo;Anne Dudeck;Mike Hasenberg;Emma Nye

  • CDC42 ACTIVITY REGULATES HEMATOPOIETIC STEM CELL AGING AND REJUVENATION

    Maria Carolina Florian;Karin Dörr;Anja Niebel;Deidre Daria

  • Antigen Presentation in Extracellular Matrix: Interactions of T Cells with Dendritic Cells Are Dynamic, Short Lived, and Sequential

    Matthias Gunzer;Matthias Gunzer;Angelika Schäfer;Stefan Borgmann;Stephan Grabbe

  • Visualizing the function and fate of neutrophils in sterile injury and repair

    Jing Wang;Jing Wang;Mokarram Hossain;Ajitha Thanabalasuriar;Matthias Gunzer

  • Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens.

    Anne Dudeck;Jan Dudeck;Julia Scholten;Anke Petzold

  • Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

    Sandra Bruns;Olaf Kniemeyer;Olaf Kniemeyer;Mike Hasenberg;Vishukumar Aimanianda

  • Co-option of Neutrophil Fates by Tissue Environments.

    Iván Ballesteros;Andrea Rubio-Ponce;Marco Genua;Eleonora Lusito

  • Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro.

    Marie-Pierre Manitz;Basil Horst;Stephan Seeliger;Anke Strey

  • Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.

    Rene Jackstadt;Sander R. van Hooff;Joshua D. Leach;Xabier Cortes-Lavaud

  • Tuning immune responses: diversity and adaptation of the immunological synapse

    Peter Friedl;Annemieke Th. den Boer;Matthias Gunzer

  • Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.

    Carlos Silvestre-Roig;Quinte Braster;Kanin Wichapong;Ernest Y. Lee

  • Human chorionic gonadotropin attracts regulatory T cells into the fetal-maternal interface during early human pregnancy.

    Anne Schumacher;Nadja Brachwitz;Sindy Sohr;Kurt Engeland

  • Microglia provide neuroprotection after ischemia.

    Jens Neumann;Matthias Gunzer;Herwig O. Gutzeit;Oliver Ullrich

  • Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

    Anika Klingberg;Anja Hasenberg;Isis Ludwig-Portugall;Anna Medyukhina

  • Microglia cells protect neurons by direct engulfment of invading neutrophil granulocytes: a new mechanism of CNS immune privilege.

    Jens Neumann;Steven Sauerzweig;Raik Rönicke;Frank Gunzer

  • STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.

    Christina Heichler;Kristina Scheibe;Anabel Schmied;Carol I Geppert

  • Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging.

    Ingo Stoffels;Stefan Morscher;Iris Helfrich;Uwe Hillen

  • Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

    Anja Hasenberg;Mike Hasenberg;Linda Männ;Franziska Neumann

  • Neutrophils instruct homeostatic and pathological states in naive tissues

    Maria Casanova-Acebes;José A. Nicolás-Ávila;Jackson LiangYao Li;Jackson LiangYao Li;Susana García-Silva

  • A network of trans-cortical capillaries as mainstay for blood circulation in long bones

    Anika Grüneboom;Ibrahim Hawwari;Daniela Weidner;Stephan Culemann

  • Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.

    Jens Neumann;Monika Riek-Burchardt;Monika Riek-Burchardt;Josephine Herz;Thorsten R. Doeppner

Frequent Co-Authors

Dirk M. Hermann
Dirk M. Hermann University of Duisburg-Essen
Stephan Grabbe
Stephan Grabbe Johannes Gutenberg University of Mainz
Peter Friedl
Peter Friedl Radboud University Medical Center
Hartmut Geiger
Hartmut Geiger University of Ulm
Burkhart Schraven
Burkhart Schraven Otto-von-Guericke University Magdeburg
Sven Brandau
Sven Brandau University of Duisburg-Essen
Axel A. Brakhage
Axel A. Brakhage Leibniz Association
Kurt S. Zänker
Kurt S. Zänker Witten/Herdecke University
Christoph Kleinschnitz
Christoph Kleinschnitz University of Duisburg-Essen
Eckhart Kämpgen
Eckhart Kämpgen University of Erlangen-Nuremberg

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