World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
42518
World Ranking
1150
National Ranking
684

Overview

Yi Zheng is affiliated with Cincinnati Children's Hospital Medical Center in the United States and has contributed extensively to research in the fields of medicine, biochemistry, genetics, and molecular biology. Their work spans a range of specialized subfields including molecular biology, oncology, immunology, hematology, and genetics.

Their scientific output includes focused research on topics such as acute myeloid leukemia, epigenetics and DNA methylation, cancer cells and metastasis, immune cells in cancer, RNA modifications and cancer, protein kinase regulation and GTPase signaling, and RNA research and splicing.

Yi Zheng has collaborated frequently with several researchers, including José A. Cancelas, Hartmut Geiger, Fukun Guo, Ashley Kuenzi Davis, and Maria Carolina Florian. These collaborations have contributed to their investigations in hematopoiesis, stem cell biology, and cancer mechanisms.

Their recent publications include investigations into inflammation and hematopoietic stem cells, aging, and genetic mutations related to myelodysplasia. Notable papers are:

  • Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs, 2020, Nature Immunology
  • Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia, 2021, Cell Stem Cell
  • Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice, 2020, Aging Cell
  • Aging of intestinal stem cells, 2022, Stem Cell Reports
  • Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity, 2021, Haematologica

Yi Zheng's work has been featured primarily in journals such as Blood, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Research, and Annals of Oncology. These venues reflect a consistent contribution to the fields of hematology and oncology.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

    Yuan Gao;J. Bradley Dickerson;Fukun Guo;Jie Zheng

  • Rho GTPase-activating proteins in cell regulation

    Sun Young Moon;Yi Zheng

  • Inhibition of RhoA by p120 catenin

    Panos Z. Anastasiadis;Sun Y. Moon;Molly A. Thoreson;Debbie J. Mariner

  • CDC42 ACTIVITY REGULATES HEMATOPOIETIC STEM CELL AGING AND REJUVENATION

    Maria Carolina Florian;Karin Dörr;Anja Niebel;Deidre Daria

  • Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

    Ling Qin;Irina Kufareva;Lauren G. Holden;Chong Wang

  • Rac1 GTPase: A “Rac” of All Trades

    E. E. Bosco;J. C. Mulloy;Y. Zheng

  • Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases.

    Joanna Liliental;Sun Young Moon;Ralf Lesche;Ramanaiah Mamillapalli

  • Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization

    Jose A Cancelas;Andrew W Lee;Rethinasamy Prabhakar;Keith F Stringer

  • Intestinal Microbiota Distinguish Gout Patients from Healthy Humans

    Zhuang Guo;Jiachao Zhang;Zhanli Wang;Kay Ying Ang

  • Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia

    Junping Wei;Mark Wunderlich;Catherine Fox;Sara Alvarez

  • Direct Desktop Printed-Circuits-on-Paper Flexible Electronics

    Yi Zheng;Zhizhu He;Yunxia Gao;Jing Liu;Jing Liu

  • A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

    Maria Carolina Florian;Kalpana J. Nattamai;Karin Dörr;Gina Marka

  • Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

    Yi Zheng;Ling Qin;Natalia V. Ortiz Zacarías;Henk de Vries

  • An essential role for Rac1 in endothelial cell function and vascular development

    Wenfu Tan;Todd R. Palmby;Julie Gavard;Panomwat Amornphimoltham

  • Cdc42 in oncogenic transformation, invasion, and tumorigenesis

    Kristy Stengel;Yi Zheng

  • Interactions among Proteins Involved in Bud-site Selection and Bud-site Assembly in Saccharomyces cerevisiae

    Yi Zheng;Alan Bender;Richard A. Cerione

  • Saccharina genomes provide novel insight into kelp biology

    Naihao Ye;Xiaowen Zhang;Miao Miao;Xiao Fan

  • Comprehensive identification of internal structure and alternative splicing events in circular RNAs

    Yuan Gao;Jinfeng Wang;Yi Zheng;Jinyang Zhang

  • Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.

    J Peterson;Y Zheng;L Bender;A Myers

Frequent Co-Authors

Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center
Hartmut Geiger
Hartmut Geiger University of Ulm
David A. Williams
David A. Williams Boston Children's Hospital
James C. Mulloy
James C. Mulloy Cincinnati Children's Hospital Medical Center
Richard A. Lang
Richard A. Lang Cincinnati Children's Hospital Medical Center
R. Michael Garavito
R. Michael Garavito Michigan State University
Nancy Ratner
Nancy Ratner Cincinnati Children's Hospital Medical Center
Tracy M. Handel
Tracy M. Handel University of Montana
Fangqing Zhao
Fangqing Zhao Chinese Academy of Sciences
Jing Liu
Jing Liu Chinese Academy of Sciences

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