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Hartmut Geiger

Hartmut Geiger

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
13980
World Ranking
11304
National Ranking
807

Overview

Hartmut Geiger is affiliated with the University of Ulm in Germany. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on aging, hematopoietic stem cells, and immune system function.

Their published work includes prominent papers such as:

  • Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice, 2020, Aging Cell
  • Targeted methods for epigenetic age predictions in mice, 2020, Scientific Reports
  • Aging of intestinal stem cells, 2022, Stem Cell Reports
  • Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity, 2021, Haematologica
  • Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems, 2023, Nature Aging

Frequent co-authors who have collaborated extensively with Hartmut Geiger include:

  • Maria Carolina Florian
  • Vadim Sakk
  • Karin Soller
  • Kalpana Nattamai
  • Mehmet Saçma

They have contributed multiple publications to several scientific journals and preprint servers, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Aging Cell
  • Blood
  • Blood Advances
  • Nature Communications

The main fields of study for Hartmut Geiger are biochemistry, genetics and molecular biology, with significant work also in medicine. Their research covers subfields including molecular biology, hematology, immunology, genetics, and oncology.

Key topics explored through their research publications are:

  • Epigenetics and DNA Methylation
  • Hematopoietic Stem Cell Transplantation
  • Cancer Cells and Metastasis
  • Single-cell and spatial transcriptomics
  • Immune Cell Function and Interaction
  • Acute Myeloid Leukemia Research
  • Wnt/β-catenin signaling in development and cancer

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

    Dagmar Walter;Amelie Lier;Anja Geiselhart;Frederic B. Thalheimer

  • CDC42 ACTIVITY REGULATES HEMATOPOIETIC STEM CELL AGING AND REJUVENATION

    Maria Carolina Florian;Karin Dörr;Anja Niebel;Deidre Daria

  • The ageing haematopoietic stem cell compartment

    Hartmut Geiger;Hartmut Geiger;Gerald de Haan;M. Carolina Florian

  • Impaired immune surveillance accelerates accumulation of senescent cells and aging

    Yossi Ovadya;Tomer Landsberger;Hanna Leins;Ezra Vadai

  • Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

    Simon Haas;Jenny Hansson;Daniel Klimmeck;Daniel Klimmeck;Dirk Loeffler

  • Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.

    Nina Cabezas-Wallscheid;Florian Buettner;Pia Sommerkamp;Daniel Klimmeck

  • The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

    Melissa Dumble;Lynette Marie Moore;Stuart M. Chambers;Hartmut Geiger

  • A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

    Maria Carolina Florian;Kalpana J. Nattamai;Karin Dörr;Gina Marka

  • The aging of lympho-hematopoietic stem cells.

    Hartmut Geiger;Gary Van Zant

  • Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.

    Linda Yang;Lei Wang;Hartmut Geiger;Jose A. Cancelas

  • G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.

    Anja Köhler;Katia De Filippo;Mike Hasenberg;Cindy van den Brandt

  • Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones.

    Anja Köhler;Vince Schmithorst;Marie-Dominique Filippi;Marnie A. Ryan

  • Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

    Kodandaramireddy Nalapareddy;Kalpana J. Nattamai;Rupali S. Kumar;Rebekah Karns

  • Increased hematopoietic stem cell mobilization in aged mice

    Zhenlan Xing;Zhenlan Xing;Marnie A. Ryan;Marnie A. Ryan;Deidre Daria;Deidre Daria;Kalpana J. Nattamai;Kalpana J. Nattamai

  • TNF-α induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells

    June Li;Daniel P. Sejas;Xiaoling Zhang;Yuhui Qiu

  • Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts

    Hartmut Geiger;Stefanie Sick;Constanze Bonifer;Albrecht M Müller

  • Aging, Clonality, and Rejuvenation of Hematopoietic Stem Cells

    Shailaja Akunuru;Hartmut Geiger

  • Unrestrained erythroblast development in Nix−/− mice reveals a mechanism for apoptotic modulation of erythropoiesis

    Abhinav Diwan;Andrew G. Koesters;Amy M. Odley;Suvarnamala Pushkaran

  • HSC Niche Biology and HSC Expansion Ex Vivo

    Sachin Kumar;Hartmut Geiger

Frequent Co-Authors

Yi Zheng
Yi Zheng Cincinnati Children's Hospital Medical Center
Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center
David A. Williams
David A. Williams Boston Children's Hospital
Gerald de Haan
Gerald de Haan University Medical Center Groningen
Andreas Trumpp
Andreas Trumpp German Cancer Research Center
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Nancy Ratner
Nancy Ratner Cincinnati Children's Hospital Medical Center
Stella M. Davies
Stella M. Davies Cincinnati Children's Hospital Medical Center
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Lars M. Steinmetz
Lars M. Steinmetz Stanford University

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