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D-Index & Metrics

Genetics

D-Index
85
Citations
38420
World Ranking
1284
National Ranking
610

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Lars M. Steinmetz is affiliated with Stanford University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans several specialized areas, including molecular biology, cardiology and cardiovascular medicine, immunology, genetics, and infectious diseases.

Steinmetz's work covers a range of topics focusing on advanced genetic and molecular mechanisms such as CRISPR and genetic engineering, RNA research and splicing, RNA and protein synthesis mechanisms, RNA modifications and cancer, single-cell and spatial transcriptomics, cardiomyopathy and myosin studies, and T-cell and B-cell immunology.

Some of the recent papers authored or co-authored by Steinmetz include:

  • High-speed fluorescence image-enabled cell sorting, 2022, Science
  • Targeted Perturb-seq enables genome-scale genetic screens in single cells, 2020, Nature Methods
  • KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19, 2022, Science
  • Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics, 2021, Nature Communications
  • Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs, 2020, Nature Medicine

Frequent co-authors working with Steinmetz include:

  • Wei Wu
  • Daniel Schraivogel
  • Andreas R. Gschwind
  • Benjamin Meder
  • Vicent Pelechano

Steinmetz's publications are seen regularly in several scientific venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science
  • Nucleic Acids Research
  • Cell Reports

This scientist has been recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • A Genome-Wide Transcriptional Analysis of the Mitotic Cell Cycle

    Raymond J. Cho;Michael J. Campbell;Elizabeth A. Winzeler;Lars Steinmetz

  • Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

    Alfredo Castello;Bernd Fischer;Katrin Eichelbaum;Rastislav Horos

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • Assembly of functionally integrated human forebrain spheroids

    Fikri Birey;Jimena Andersen;Christopher D. Makinson;Saiful Islam

  • Bidirectional promoters generate pervasive transcription in yeast

    Zhenyu Xu;Wu Wei;Julien Gagneur;Fabiana Perocchi

  • Evolutionary Rate in the Protein Interaction Network

    Hunter B. Fraser;Aaron E. Hirsh;Lars M. Steinmetz;Curt Scharfe

  • Ultrasensitive proteome analysis using paramagnetic bead technology

    Christopher S Hughes;Sophia Foehr;David A Garfield;Eileen E Furlong

  • Role of duplicate genes in genetic robustness against null mutations.

    Zhenglong Gu;Lars M. Steinmetz;Xun Gu;Curt Scharfe

  • Human haematopoietic stem cell lineage commitment is a continuous process

    Lars Velten;Simon F. Haas;Simon Raffel;Simon Raffel;Sandra Blaszkiewicz

  • A high-resolution map of transcription in the yeast genome

    Lior David;Wolfgang Huber;Marina Granovskaia;Joern Toedling

  • Gene regulation by antisense transcription

    Vicent Pelechano;Lars M. Steinmetz

  • Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

    Erwei Zuo;Yidi Sun;Wu Wei;Wu Wei;Wu Wei;Tanglong Yuan

  • Dissecting the architecture of a quantitative trait locus in yeast

    Lars M. Steinmetz;Himanshu Sinha;Dan R. Richards;Jamie I. Spiegelman

  • Widespread bidirectional promoters are the major source of cryptic transcripts in yeast

    Helen Neil;Christophe Malabat;Yves d'Aubenton-Carafa;Zhenyu Xu

  • High-resolution mapping of meiotic crossovers and non-crossovers in yeast

    Eugenio Mancera;Richard Bourgon;Alessandro Brozzi;Wolfgang Huber

  • Systematic screen for human disease genes in yeast

    Lars M. Steinmetz;Curt Scharfe;Adam M. Deutschbauer;Dejana Mokranjac

  • Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.

    Chiara Baccin;Chiara Baccin;Jude Al-Sabah;Lars Velten;Patrick M. Helbling

  • Transcriptional regulation and function during the human cell cycle.

    Raymond J. Cho;Mingxia Huang;Michael J. Campbell;Helin Dong

  • The Genomic and Transcriptomic Landscape of a HeLa Cell Line

    Jonathan J M Landry;Paul Theodor Pyl;Tobias Rausch;Thomas Zichner

  • A new fate mapping system reveals context-dependent random or clonal expansion of microglia

    Tuan Leng Tay;Dominic Mai;Jana Dautzenberg;Francisco Fernández-Klett

Frequent Co-Authors

Julien Gagneur
Julien Gagneur Technical University of Munich
Ronald W. Davis
Ronald W. Davis Stanford University
Wolfgang Huber
Wolfgang Huber European Bioinformatics Institute
Michael Snyder
Michael Snyder Stanford University
Andreas Trumpp
Andreas Trumpp German Cancer Research Center
Peter J. Oefner
Peter J. Oefner University of Regensburg
Leopold Parts
Leopold Parts Wellcome Sanger Institute
Jeroen Krijgsveld
Jeroen Krijgsveld German Cancer Research Center
Nicholas M. Luscombe
Nicholas M. Luscombe The Francis Crick Institute
Utkan Demirci
Utkan Demirci Stanford University

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