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Biology and Biochemistry

D-Index
72
Citations
30742
World Ranking
6135
National Ranking
2878

Overview

Lucia R. Languino is affiliated with Thomas Jefferson University in the United States. Their research primarily focuses on molecular biology and medicine, with a particular interest in cancer research and biochemistry.

Their work has contributed to multiple fields of study, including:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, their subfields of study encompass:

  • Molecular Biology
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine
  • Cancer Research
  • Epidemiology

The main topics of Lucia R. Languino's research include:

  • Cell Adhesion Molecules Research
  • Extracellular vesicles in disease
  • Prostate Cancer Treatment and Research
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • RNA Research and Splicing

The scientist has published extensively, with frequent appearances in several publication venues. These include:

  • Journal of Extracellular Vesicles
  • Cancer Research
  • Scientific Reports
  • Journal of Clinical Oncology
  • Cancer Biology & Therapy

Some of the recent research papers authored or co-authored by Lucia R. Languino are:

  • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019 (2020), Journal of Clinical Oncology
  • The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells (2020), Science Signaling
  • The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis (2020), Journal of Extracellular Vesicles
  • STEAP1-4 (Six-Transmembrane Epithelial Antigen of the Prostate 1-4) and Their Clinical Implications for Prostate Cancer (2022), Cancers
  • Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment (2020), Developmental Cell

Frequent collaborators include the following co-authors, with multiple joint publications:

  • William Kevin Kelly
  • Dario C. Altieri
  • Nicole M. Naranjo
  • Cecilia E. Verrillo
  • Fabio Quaglia

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

    Wayne A. Border;Seiya Okuda;Lucia R. Languino;Michael B. Sporn

  • Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

    Seiya Okuda;Lucia R. Languino;Erkki Ruoslahti;Wayne A. Border

  • Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors

    Vinit Kumar;Laxminarasimha Donthireddy;Douglas Marvel;Thomas Condamine

  • Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt

    Manuel Morales-Ruiz;David Fulton;Grzegorz Sowa;Lucia R. Languino

  • Transforming growth factor-β regulates production of proteoglycans by mesangial cells

    Wayne A. Border;Wayne A. Border;Seiya Okuda;Seiya Okuda;Lucia R. Languino;Lucia R. Languino;Erkki Ruoslahti;Erkki Ruoslahti

  • Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.

    L R Languino;K R Gehlsen;E Wayner;W G Carter

  • Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway

    Lucia R. Languino;Janet Plescia;Alain Duperray;Adrienne A. Brian

  • The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion

    Jitesh Pratap;Amjad Javed;Lucia R. Languino;Andre J. van Wijnen

  • Alpha 2 beta 1 integrins from different cell types show different binding specificities.

    D Kirchhofer;L R Languino;E Ruoslahti;M D Pierschbacher

  • Runx2 association with progression of prostate cancer in patients: Mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

    J. Akech;J. J. Wixted;K. Bedard;M. Van Der Deen

  • CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

    Vinit Kumar;Pingyan Cheng;Thomas Condamine;Sridevi Mony

  • IAP Regulation of Metastasis

    Swarna Mehrotra;Lucia R. Languino;Christopher M. Raskett;Arthur M. Mercurio

  • Prostatic carcinoma cell migration via alpha(v)beta3 integrin is modulated by a focal adhesion kinase pathway.

    Duo-Qi Zheng;Amy S. Woodard;Mara Fornaro;Giovanni Tallini

  • Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.

    S Suzuki;W S Argraves;H Arai;L R Languino

  • Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding.

    E Dejana;L R Languino;N Polentarutti;G Balconi

  • Regulation of survivin expression by IGF-1/mTOR signaling.

    V Vaira;C W Lee;H L Goel;S Bosari

  • The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration

    Amy S. Woodard;Guillermo García-Cardeña;Margaret Leong;Joseph A. Madri

  • TRAP-1, the mitochondrial Hsp90.

    Dario C. Altieri;Gary S. Stein;Jane B. Lian;Lucia R. Languino

  • The integrin-growth factor receptor duet.

    Naved Alam;Hira Lal Goel;Matthew J. Zarif;Julie E. Butterfield

Frequent Co-Authors

Dario C. Altieri
Dario C. Altieri The Wistar Institute
Andrew V. Kossenkov
Andrew V. Kossenkov The Wistar Institute
Jane B. Lian
Jane B. Lian University of Vermont
Gary S. Stein
Gary S. Stein University of Vermont
Silvano Bosari
Silvano Bosari University of Milan
Dmitry I. Gabrilovich
Dmitry I. Gabrilovich AstraZeneca (United Kingdom)
David W. Speicher
David W. Speicher The Wistar Institute
Elisabetta Dejana
Elisabetta Dejana Uppsala University
Edward F. Plow
Edward F. Plow Cleveland Clinic Lerner College of Medicine
Janet L. Stein
Janet L. Stein University of Vermont

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