David W. Speicher

Overview

Best Publications

• Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

  Robert E. Handschumacher;Matthew W. Harding;Jeffrey Rice;Rhett J. Drugge

  2364
  Citations

• Nuclear lamin-A Scales With Tissue Stiffness and Enhances Matrix-Directed Differentiation

  Joe Swift;Irena L. Ivanovska;Amnon Buxboim;Takamasa Harada

  1941
  Citations

• Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

  Adam J. Engler;Christine Carag-Krieger;Colin P. Johnson;Matthew Raab

  987
  Citations

• Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.

  Gilbert S. Omenn;David J. States;Marcin Adamski;Thomas W. Blackwell

  830
  Citations

• KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

  Josh R. Friedman;William J. Fredericks;David E. Jensen;David W. Speicher

  792
  Citations

• Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

  Alexander Roesch;Adina Vultur;Ivan Bogeski;Huan Wang

  738
  Citations

• Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A -mutated cancers

  Benjamin G. Bitler;Katherine M. Aird;Azat Garipov;Hua Li

  648
  Citations

• Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors

  Vinit Kumar;Laxminarasimha Donthireddy;Douglas Marvel;Thomas Condamine

  647
  Citations

• HUPO Plasma Proteome Project specimen collection and handling : Towards the standardization of parameters for plasma proteome samples

  Alex J. Rai;Craig A. Gelfand;Bruce C. Haywood;David J. Warunek

  618
  Citations

• Erythrocyte spectrin is comprised of many homologous triple helical segments

  David W. Speicher;Vincent T. Marchesi

  569
  Citations

• Depletion of multiple high-abundance proteins improves protein profiling capacities of human serum and plasma.

  Lynn A. Echan;Hsin-Yao Tang;Nadeem Ali-Khan;KiBeom Lee

  509
  Citations

• Forced Unfolding of Proteins Within Cells

  Colin P. Johnson;Hsin-Yao Tang;Christine Carag;David W. Speicher

  448
  Citations

• A HUPO test sample study reveals common problems in mass spectrometry–based proteomics

  Alexander W. Bell;Eric W. Deutsch;Catherine E. Au;Robert E. Kearney

  407
  Citations

• The Proteome of the Mouse Photoreceptor Sensory Cilium Complex

  Qin Liu;Glenn Tan;Natasha Levenkova;Tiansen Li

  400
  Citations

• Isolation and amino acid sequence of cyclophilin

  M W Harding;R E Handschumacher;D W Speicher

  384
  Citations

• sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

  Amanpreet Kaur;Amanpreet Kaur;Marie R. Webster;Katie Marchbank;Reeti Behera

  377
  Citations

• A chromatin remodelling complex that loads cohesin onto human chromosomes

  Mohamed-Ali Hakimi;Daniel A. Bochar;John A. Schmiesing;Yuanshu Dong

  363
  Citations

• Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

  Amanpreet Kaur;Amanpreet Kaur;Amanpreet Kaur;Brett L. Ecker;Stephen M. Douglass;Curtis H. Kugel

  327
  Citations

• Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study.

  David J States;Gilbert S Omenn;Thomas W Blackwell;Damian Fermin

  315
  Citations

• The Proteome of the Mouse Photoreceptor Sensory Cilium

  Glenn Tan;Edward N. Pugh;David W. Speicher;Eric A. Pierce

  23
  Citations