World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
111
Citations
42122
World Ranking
480
National Ranking
42

Medicine

D-Index
112
Citations
42307
World Ranking
5179
National Ranking
512

Research.com Recognitions

  • 2016 - Member of Academia Europaea

Overview

Ian Kimber is affiliated with the University of Manchester in the United Kingdom. Their research primarily focuses on the field of medicine, with significant contributions in dermatology, immunology and allergy, small animals, physiology, and plant science. The scientist's work engages deeply with topics related to contact dermatitis and allergies, animal testing and alternatives, allergic rhinitis and sensitization, food allergy and anaphylaxis research, pesticide exposure and toxicity, occupational exposure and asthma, and CAR-T cell therapy research.

Kimber has published extensively in several academic venues, notably contributing to Regulatory Toxicology and Pharmacology, Critical Reviews in Toxicology, Human Gene Therapy, Toxicology Letters, and Frontiers in Molecular Neuroscience. The majority of published work appears in Regulatory Toxicology and Pharmacology.

Recent papers by Ian Kimber include:

  • Determination of the relative allergenic potency of proteins: hurdles and opportunities, 2020, Critical Reviews in Toxicology
  • Reference Chemical Potency List (RCPL): A new tool for evaluating the accuracy of skin sensitisation potency measurements by New Approach Methodologies (NAMs), 2022, Regulatory Toxicology and Pharmacology
  • Enzymes and sensitization via skin exposure: A critical analysis, 2021, Regulatory Toxicology and Pharmacology
  • Specificity of the local lymph node assay (LLNA) for skin sensitisation, 2023, Regulatory Toxicology and Pharmacology
  • Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article, 2024, Human Gene Therapy

Frequent co-authors collaborating with Ian Kimber include Amaia Irizar, Peter Griem, Andreas Natsch, Hans Bender, and Matthias Vey. These collaborations highlight a multidisciplinary approach within allied research areas.

Kimber's research themes cover a broad spectrum of medical topics, with particular emphasis on allergic reactions and toxicity assessments relevant to human health and safety. Contact dermatitis and allergies feature prominently as a central research interest, supported by studies investigating allergenic protein potency, skin sensitization assays, and risk factors associated with therapeutic interventions such as gene therapies.

In recognition of their academic contributions, Ian Kimber was named a Member of Academia Europaea in 2016, reflecting involvement in the broader scientific community.

Best Publications

  • Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.

    David W. Roberts;Grace Patlewicz;Petra S. Kern;Frank Gerberick

  • Immunogenicity of therapeutic proteins: Influence of aggregation

    Kirsty D. Ratanji;Jeremy P. Derrick;Rebecca J. Dearman;Ian Kimber

  • Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

    Sarah Adler;David Basketter;Stuart Creton;Olavi Pelkonen

  • Food processing and allergenicity

    Kitty C.M. Verhoeckx;Yvonne M. Vissers;Joseph L. Baumert;Roland Faludi

  • Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migration.

    M Cumberbatch;R J Dearman;I Kimber

  • Assessment of the safety of foods derived from genetically modified (GM) crops

    A. König;A. Cockburn;R.W.R. Crevel;E. Debruyne

  • Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods

    G. Frank Gerberick;Cindy A. Ryan;Petra S. Kern;Harald Schlatter

  • Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration.

    M Cumberbatch;I Kimber

  • The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

    L. M. Hamilton;C. Torres-Lozano;S. M. Puddicombe;A. Richter

  • Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects Current knowledge assembled at an international workshop at BfR, Germany

    M. Peiser;T. Tralau;J. Heidler;A. M. Api

  • Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies.

    Louisa K. James;Mohamed H. Shamji;Samantha M. Walker;Duncan R. Wilson

  • The murine local lymph node assay: a commentary on collaborative studies and new directions.

    I. Kimber;D.A. Basketter

  • A murine local lymph node assay for the identification of contact allergens. Assay development and results of an initial validation study

    I. Kimber;C. Weisenberger

  • Why Are Some Proteins Allergens

    Russell D. J. Huby;Rebecca J. Dearman;Ian Kimber

  • Tumour necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization.

    M Cumberbatch;I Kimber

  • The local lymph node assay: developments and applications.

    I. Kimber;R.J. Dearman;E.W. Scholes;D.A. Basketter

  • The effects of ultraviolet radiation on the human immune system

    M S Duthie;I Kimber;M Norval

  • Classification of contact allergens according to potency: proposals.

    I Kimber;D.A Basketter;M Butler;A Gamer

  • A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses.

    David A. Basketter;Linda J Lea;Andrea Dickens;David Briggs

  • Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy

    M. H. Shamji;C. Ljørring;J. N. Francis;M. A Calderon

  • Use of the local lymph node assay for the estimation of relative contact allergenic potency.

    D. A. Basketter;L. Blaikie;R. J. Dearman;I. Kimber

Frequent Co-Authors

Rebecca J. Dearman
Rebecca J. Dearman University of Manchester
David A. Basketter
David A. Basketter University of Bedfordshire
Marie Cumberbatch
Marie Cumberbatch AstraZeneca (United Kingdom)
Cindy A. Ryan
Cindy A. Ryan Procter & Gamble (United States)
G. Frank Gerberick
G. Frank Gerberick Procter & Gamble (United States)
Christopher E.M. Griffiths
Christopher E.M. Griffiths University of Manchester
John Ashby
John Ashby Syngenta (Switzerland)
Michael Moore
Michael Moore Plymouth Marine Laboratory
Nancy J. Rothwell
Nancy J. Rothwell University of Manchester
Mary Norval
Mary Norval University of Edinburgh

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