John Ashby

Overview

Best Publications

• Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

  John Ashby;Raymond W. Tennant

  1040
  Citations

• Some Alkyl Hydroxy Benzoate Preservatives (Parabens) Are Estrogenic

  Edwin J. Routledge;Joanne Parker;Jenny Odum;John Ashby

  979
  Citations

• Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP.

  John Ashby;Raymond W. Tennant

  938
  Citations

• An evaluation of 6 short-term tests for detecting organic chemical carcinogens

  I F Purchase;E Longstaff;J Ashby;J A Styles

  736
  Citations

• Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis:

  J. Ashby;A. Brady;C.R. Elcombe;B.M. Elliott

  439
  Citations

• The rodent uterotrophic assay: Critical protocol features, studies with nonyl phenols, and comparison with a yeast estrogenicity assay

  J. Odum;P.A. Lefevre;S. Tittensor;D. Paton

  365
  Citations

• International Commission for Protection Against Environmental Mutagens and Carcinogens. Genotoxicity under extreme culture conditions. A report from ICPEMC Task Group 9

  David Scott;Sheila M. Galloway;Richard R. Marshall;Motoi Ishidate

  354
  Citations

• Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use

  I. F. H. Purchase;E. Longstaff;John Ashby;J. A. Styles

  331
  Citations

• Classification according to chemical structure, mutagenicity to Salmonella and level of carcinogenicity of a further 39 chemicals tested for carcinogenicity by the U.S. National Toxicology Program.

  Raymond W. Tennant;John Ashby

  318
  Citations

• The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: phase 1.

  Jun Kanno;Lesley Onyon;Joseph Haseman;Penelope Fenner-Crisp

  268
  Citations

• The single cell gel electrophoresis assay for induced DNA damage (comet assay): measurement of tail length and moment.

  J. Ashby;H. Tinwell;P.A. Lefevre;M.A. Browne

  238
  Citations

• Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity

  John Ashby

  235
  Citations

• The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens.

  John Ashby

  201
  Citations

• Does carcinogenic potency correlate with mutagenic potency in the Ames assay

  John Ashby;J. A. Styles

  194
  Citations

• Safety evaluation of phytosterol esters. Part 1. Assessment of oestrogenicity using a combination of in vivo and in vitro assays.

  V.A Baker;P.A Hepburn;S.J Kennedy;P.A Jones

  192
  Citations

• The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators

  J. Ashby;P. A. Lefevre

  178
  Citations

• The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dose-response studies

  Jun Kanno;Lesley Onyon;Shyamal Peddada;John Ashby

  169
  Citations

• Structure activity relationships in skin sensitization using the murine local lymph node assay

  J Ashby;D A Basketter;D Paton;I Kimber

  165
  Citations

• Critical review and evaluation of the uterotrophic bioassay for the identification of possible estrogen agonists and antagonists: in support of the validation of the OECD uterotrophic protocols for the laboratory rodent. Organisation for Economic Co-operation and Development.

  J William Owens;John Ashby

  157
  Citations

• Phenotypic Anchoring of Gene Expression Changes during Estrogen-Induced Uterine Growth

  Jonathan G. Moggs;Helen Tinwell;Tracey Spurway;Hur Song Chang

  152
  Citations