His primary areas of study are Genotoxicity, In vivo, In vitro, Toxicity and Pharmacology. His Genotoxicity study integrates concerns from other disciplines, such as Toxicology, Micronucleus, Micronucleus test and Cytotoxicity. His study looks at the relationship between Toxicology and fields such as Risk analysis, as well as how they intersect with chemical problems.
His In vivo research is multidisciplinary, relying on both Clastogen and Carcinogen. His study looks at the intersection of Clastogen and topics like Molecular biology with Cancer research, Mutagen and Comet assay. His work in the fields of Toxicity, such as Oecd guideline, intersects with other areas such as Human exposure, Mechanism and Mitotic index.
Genotoxicity, In vivo, Pharmacology, Micronucleus test and In vitro are his primary areas of study. His study in Genotoxicity is interdisciplinary in nature, drawing from both Toxicology, Micronucleus and Carcinogen. His In vivo study combines topics from a wide range of disciplines, such as Molecular biology and Comet assay.
His research investigates the link between Pharmacology and topics such as Genetics that cross with problems in Chromosome aberration. His research integrates issues of Metaphase, Immunology, Bone marrow and Cytochalasin B in his study of Micronucleus test. His In vitro research is multidisciplinary, incorporating elements of Apoptosis and Mammalian cell.
His primary areas of study are Genotoxicity, Carcinogen, In vivo, Pharmacology and Gene mutation. His studies in Genotoxicity integrate themes in fields like In vitro, Toxicology and Micronucleus test. His biological study spans a wide range of topics, including Genetic Toxicology, Mode of action and Biotechnology.
His In vivo research is multidisciplinary, relying on both Molecular biology, Micronucleus and Comet assay. Micronucleus is a subfield of Toxicity that David Kirkland tackles. His studies deal with areas such as Glyphosate and International agency as well as Pharmacology.
His main research concerns Genotoxicity, Carcinogen, International agency, Glyphosate and Pharmacology. The various areas that David Kirkland examines in his Genotoxicity study include In vivo and Micronucleus test. His In vivo study incorporates themes from Cell culture, In vitro, Apoptosis, Immunology and Molecular biology.
His International agency study combines topics in areas such as Carcinogenesis Mechanism and Aminomethylphosphonic acid. Pharmacology is connected with Ames test and Gene mutation in his research. As part of one scientific family, he deals mainly with the area of Genetic Toxicology, narrowing it down to issues related to the Risk analysis, and often Genetics.
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Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens: I. Sensitivity, specificity and relative predictivity
David Kirkland;Marilyn Aardema;Leigh Henderson;Lutz Müller.
Mutation Research (2005)
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens: III. Appropriate follow-up testing in vivo
David Kirkland;Günter Speit.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2005)
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
David Kirkland;Stefan Pfuhler;David Tweats;Marilyn Aardema.
Mutation Research (2007)
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
David Kirkland;Lesley Reeve;David Gatehouse;Philippe Vanparys.
Mutation Research (2011)
Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type.
Paul Fowler;Katie Smith;Jamie Young;Laura Jeffrey.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2012)
Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: a follow-up to an ECVAM workshop.
David Kirkland;Peter Kasper;Lutz Müller;Raffaella Corvi.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2008)
Clastogenicity, photo-clastogenicity or pseudo-photo-clastogenicity: Genotoxic effects of zinc oxide in the dark, in pre-irradiated or simultaneously irradiated Chinese hamster ovary cells.
Eric K. Dufour;Tirukalikundram Kumaravel;Gerhard J. Nohynek;David Kirkland.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2006)
Report from working group on in vitro tests for chromosomal aberrations.
Sheila M. Galloway;Marilyn J. Aardema;Motoi Ishidate;James L. Ivett.
Mutation Research (1994)
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles.
David Kirkland;Marilyn Aardema;Lutz Müller;Hayashi Makoto.
Mutation Research (2006)
Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds.
David J Kirkland;Lutz Müller.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2000)
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