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Richard A. Padgett

Richard A. Padgett

D-Index & Metrics

Molecular Biology

D-Index
44
Citations
14068
World Ranking
2892
National Ranking
1377

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Richard A. Padgett is affiliated with the Cleveland Clinic in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields, focusing notably on molecular biology, hematology, cell biology, cancer research, and genetics.

The scientist's research topics include RNA research and splicing, acute myeloid leukemia research, RNA modifications and cancer, RNA and protein synthesis mechanisms, interferon and immune responses, mosquito-borne diseases and control, and zebrafish biomedical research applications.

Frequent co-authors of Richard A. Padgett include:

  • Courtney E. Hershberger
  • Jaroslaw P. Maciejewski
  • Torsten Haferlach
  • Noah J. Daniels
  • Carmelo Gurnari

The venues where Padgett often publishes include:

  • Blood
  • Leukemia
  • Developmental Cell
  • Cell Stem Cell
  • Nucleic Acids Research

Among recent publications are:

  • "Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production" (2021, Developmental Cell)
  • "Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia" (2021, Cell Stem Cell)
  • "Comprehensive database and evolutionary dynamics of U12-type introns" (2020, Nucleic Acids Research)
  • "Complex landscape of alternative splicing in myeloid neoplasms" (2020, Leukemia)
  • "Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms" (2021, Cell Reports)

Richard A. Padgett has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) twice, in 2013 and again in 2017.

Best Publications

  • Splicing of Messenger RNA Precursors

    Phillip A. Sharp;Stephen Hardy;Richard A. Padgett

  • Rapid DNA isolations for enzymatic and hybridization analysis.

    Ronald W. Davis;Marjorie Thomas;John Cameron;Thomas P. St. John

  • Recognition of cap structure in splicing in vitro of mRNA precursors

    Maria M. Konarska;Richard A. Padgett;Phillip A. Sharp

  • Splicing of Messenger RNA Precursors

    Phillip A. Sharp

  • Rates of in situ transcription and splicing in large human genes.

    Jarnail Singh;Richard A Padgett

  • Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

    Richard A. Padgett;Maria M. Konarska;Maria M. Konarska;Paula J. Grabowski;Steven F. Hardy

  • Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

    G M Wahl;R A Padgett;G R Stark

  • Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis.

    Hideki Makishima;Valeria Visconte;Hirotoshi Sakaguchi;Anna M. Jankowska

  • Biased chromatin signatures around polyadenylation sites and exons.

    Noah Spies;Cydney B. Nielsen;Richard A. Padgett;Christopher B. Burge

  • Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

    Chantana Polprasert;Isabell Schulze;Mikkael Sekeres;Hideki Makishima

  • Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA.

    M. Aebi;H. Hornig;R.A. Padgett;J. Reiser

  • Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein

    Richard A. Padgett;Stephen M. Mount;Joan A. Steitz;Phillip A. Sharp

  • Evolutionary Fates and Origins of U12-Type Introns

    Christopher B. Burge;Richard A. Padgett;Phillip A. Sharp

  • Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites.

    Stephen L. Hall;Richard A. Padgett

  • Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns.

    Stephen L. Hall;Richard A. Padgett

  • Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate

    Paula J. Grabowski;Richard A. Padgett;Phillip A. Sharp

  • Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I

    Huiling He;Sandya Liyanarachchi;Keiko Akagi;Rebecca Nagy

  • Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

    Maria M. Konarska;Maria M. Konarska;Paula J. Grabowski;Richard A. Padgett;Phillip A. Sharp

  • Trans splicing of mrna precursors in vitro

    Maria M. Konarska;Richard A. Padgett;Phillip A. Sharp

  • New connections between splicing and human disease.

    Richard A. Padgett

Frequent Co-Authors

Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Mikkael A. Sekeres
Mikkael A. Sekeres Cleveland Clinic
Seishi Ogawa
Seishi Ogawa Kyoto University
Yuichi Shiraishi
Yuichi Shiraishi University of Tokyo
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Torsten Haferlach
Torsten Haferlach MLL Munich Leukemia Laboratory
kenichi yoshida
kenichi yoshida Kyoto University
Carsten Müller-Tidow
Carsten Müller-Tidow University Hospital Heidelberg

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