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Mikkael A. Sekeres

Mikkael A. Sekeres

D-Index & Metrics

Medicine

D-Index
99
Citations
41709
World Ranking
8508
National Ranking
4390

Overview

Mikkael A. Sekeres is affiliated with the Cleveland Clinic in the United States. Their research primarily focuses on Medicine, with a significant contribution to the subfields of Hematology, Genetics, Molecular Biology, Public Health, Environmental and Occupational Health, and Oncology. Their work spans various topics including Acute Myeloid Leukemia Research, Myeloproliferative Neoplasms: Diagnosis and Treatment, Chronic Myeloid Leukemia Treatments, Acute Lymphoblastic Leukemia Research, Hemoglobinopathies and Related Disorders, Histone Deacetylase Inhibitors Research, and Chronic Lymphocytic Leukemia Research.

They have authored numerous papers, with notable recent publications including:

  • Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA, 2020, Annals of Oncology
  • Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes, 2020, New England Journal of Medicine
  • Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes, 2021, Journal of Clinical Oncology
  • Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia (QuANTUM-First): a randomised, double-blind, placebo-controlled, phase 3 trial, 2023, The Lancet
  • SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS, 2020, Blood

Frequent co-authors in Sekeres's publications include:

  • Rami S. Komrokji (128 collaborations)
  • Valeria Santini (90 collaborations)
  • Amer M. Zeidan (85 collaborations)
  • Michael R. Savona (83 collaborations)
  • Uwe Platzbecker (81 collaborations)

Their work is frequently published in the following venues:

  • Blood (114 publications)
  • Clinical Lymphoma Myeloma & Leukemia (58 publications)
  • Journal of Clinical Oncology (32 publications)
  • Leukemia (15 publications)
  • Blood Advances (13 publications)

Mikkael A. Sekeres has also contributed to book publications under The MIT Press, including the titles "Drugs and the FDA" (2022) and "When Blood Breaks Down" (2020).

Best Publications

  • Revised International Prognostic Scoring System for Myelodysplastic Syndromes

    Peter L. Greenberg;Heinz Tuechler;Julie Schanz;Guillermo Sanz

  • Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

    David P. Steensma;Rafael Bejar;Siddhartha Jaiswal;R. Coleman Lindsley

  • Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia

    Eytan M. Stein;Eytan M. Stein;Courtney D. DiNardo;Daniel A. Pollyea;Amir T. Fathi

  • Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

    C. D. DiNardo;E. M. Stein;S. De Botton;G. J. Roboz

  • Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

    M C Liu;G R Oxnard;E A Klein;C Swanton

  • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

    Ying Jiang;Andrew Dunbar;Lukasz P. Gondek;Sanjay Mohan

  • Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

    Pierre Fenaux;Pierre Fenaux;Uwe Platzbecker;Ghulam J. Mufti;Guillermo Garcia-Manero

  • Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis.

    Hideki Makishima;Valeria Visconte;Hirotoshi Sakaguchi;Anna M. Jankowska

  • STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

    Andres Jerez;Michael J. Clemente;Hideki Makishima;Hanna Koskela

  • Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

    Chantana Polprasert;Isabell Schulze;Mikkael Sekeres;Hideki Makishima

  • 250K Single Nucleotide Polymorphism Array Karyotyping Identifies Acquired Uniparental Disomy and Homozygous Mutations, Including Novel Missense Substitutions of c-Cbl, in Myeloid Malignancies

    Andrew J Dunbar;Lukasz P Gondek;Christine L O'Keefe;Hideki Makishima

  • Dynamics of clonal evolution in myelodysplastic syndromes

    Hideki Makishima;Hideki Makishima;Tetsuichi Yoshizato;Kenichi Yoshida;Mikkael Sekeres

  • Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

    Lukasz P. Gondek;Ramon Tiu;Christine L. O'Keefe;Mikkael A. Sekeres

  • Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

    Anna M. Jankowska;Hideki Makishima;Ramon V. Tiu;Hadrian Szpurka

  • Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms.

    F. Traina;V. Visconte;Paul Elson;A. Tabarroki

  • Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes.

    David A Sallman;Amy E DeZern;Guillermo Garcia-Manero;David P Steensma

  • Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

    Eytan M. Stein;Eytan M. Stein;Courtney D. DiNardo;Amir T. Fathi;Daniel A. Pollyea

  • Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation.

    Tetsuichi Yoshizato;Yasuhito Nannya;Yoshiko Atsuta;Yusuke Shiozawa;Yusuke Shiozawa

  • Characteristics of US Patients with Myelodysplastic Syndromes: Results of Six Cross-sectional Physician Surveys

    Mikkael A. Sekeres;W. Marieke Schoonen;Hagop M Kantarjian;Alan List

  • Enasidenib in mutant-IDH2 relapsed or refractory acute myeloid leukemia (R/R AML): Results of a phase I dose-escalation and expansion study.

    Eytan M. Stein;Courtney Denton Dinardo;Daniel Aaron Pollyea;Amir Tahmasb Fathi

Frequent Co-Authors

Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Alan F. List
Alan F. List Precision BioSciences
Guillermo Garcia-Manero
Guillermo Garcia-Manero The University of Texas MD Anderson Cancer Center
David P. Steensma
David P. Steensma Harvard University
Pierre Fenaux
Pierre Fenaux Université Paris Cité
Hagop M. Kantarjian
Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center
Seishi Ogawa
Seishi Ogawa Kyoto University
Richard Stone
Richard Stone Harvard University
Torsten Haferlach
Torsten Haferlach MLL Munich Leukemia Laboratory
Lisa Rybicki
Lisa Rybicki Cleveland Clinic

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