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Jaroslaw P. Maciejewski

Jaroslaw P. Maciejewski

D-Index & Metrics

Medicine

D-Index
120
Citations
52616
World Ranking
3757
National Ranking
2067

Overview

Jaroslaw P. Maciejewski is affiliated with the Cleveland Clinic in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology.

The scientist's work spans several subfields, including hematology, genetics, molecular biology, immunology, and cancer research. Key topics covered in their research include acute myeloid leukemia, myeloproliferative neoplasms, chronic myeloid leukemia treatments, the complement system in diseases, cancer genomics and diagnostics, blood groups and transfusion, and chronic lymphocytic leukemia research.

Maciejewski has contributed a significant body of scholarly articles, with frequent publication venues being:

  • Blood
  • Leukemia
  • Clinical Lymphoma Myeloma & Leukemia
  • Journal of Clinical Oncology
  • Blood Advances

Some of the recent notable papers include:

  • SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS, 2020, Blood
  • Molecular landscape and clonal architecture of adult myelodysplastic/myeloproliferative neoplasms, 2020, Blood
  • Baseline clinical characteristics and disease burden in patients with paroxysmal nocturnal hemoglobinuria (PNH): updated analysis from the International PNH Registry, 2020, Annals of Hematology
  • Germ lineDDX41mutations define a unique subtype of myeloid neoplasms, 2022, Blood
  • Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria, 2020, Haematologica

Frequent collaborators in their research efforts include Carmelo Gurnari, Valeria Visconte, Simona Pagliuca, Arda Durmaz, and Hetty E. Carraway.

Best Publications

  • Revised International Prognostic Scoring System for Myelodysplastic Syndromes

    Peter L. Greenberg;Heinz Tuechler;Julie Schanz;Guillermo Sanz

  • The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.

    Peter Hillmen;Neal S. Young;Jörg Schubert;Robert A. Brodsky

  • Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

    Myunggon Ko;Yun Huang;Yun Huang;Anna M. Jankowska;Utz J. Pape;Utz J. Pape

  • Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

    Hanna L.M. Koskela;Samuli Eldfors;Pekka Ellonen;Arjan J. van Adrichem

  • Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.

    Robert A. Brodsky;Neal S. Young;Elisabetta Antonioli;Antonio M. Risitano

  • The pathophysiology of acquired aplastic anemia.

    Neal S. Young;Jaroslaw Maciejewski

  • Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

    Tetsuichi Yoshizato;Bogdan Dumitriu;Kohei Hosokawa;Hideki Makishima

  • Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

    Jaroslaw Maciejewski;Carmine Selleri;Stacie Anderson;Neal S. Young

  • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

    Ying Jiang;Andrew Dunbar;Lukasz P. Gondek;Sanjay Mohan

  • Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis.

    Hideki Makishima;Valeria Visconte;Hirotoshi Sakaguchi;Anna M. Jankowska

  • STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

    Andres Jerez;Michael J. Clemente;Hideki Makishima;Hanna Koskela

  • Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

    Peter Hillmen;Petra Muus;Alexander Roth;Modupe O. Elebute

  • Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

    Chantana Polprasert;Isabell Schulze;Mikkael Sekeres;Hideki Makishima

  • Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms.

    Anna M. Jankowska;Hadrian Szpurka;Ramon V. Tiu;Hideki Makishima

  • 250K Single Nucleotide Polymorphism Array Karyotyping Identifies Acquired Uniparental Disomy and Homozygous Mutations, Including Novel Missense Substitutions of c-Cbl, in Myeloid Malignancies

    Andrew J Dunbar;Lukasz P Gondek;Christine L O'Keefe;Hideki Makishima

  • Dynamics of clonal evolution in myelodysplastic syndromes

    Hideki Makishima;Hideki Makishima;Tetsuichi Yoshizato;Kenichi Yoshida;Mikkael Sekeres

  • Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents.

    Marcin W. Wlodarski;Marcin W. Wlodarski;Shinsuke Hirabayashi;Victor Pastor;Jan Starý

  • Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

    Lukasz P. Gondek;Ramon Tiu;Christine L. O'Keefe;Mikkael A. Sekeres

  • HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome.

    Yogen Saunthararajah;Ryotaro Nakamura;Jun Mo Nam;Jamie Robyn

  • Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

    Hanna L. M. Rajala;Samuli Eldfors;Heikki Kuusanmäki;Arjan J. van Adrichem

Frequent Co-Authors

Mikkael A. Sekeres
Mikkael A. Sekeres Cleveland Clinic
Alan F. List
Alan F. List Precision BioSciences
Seishi Ogawa
Seishi Ogawa Kyoto University
Neal S. Young
Neal S. Young National Institutes of Health
Michael A. McDevitt
Michael A. McDevitt Johns Hopkins University
Eric D. Hsi
Eric D. Hsi Cleveland Clinic
Torsten Haferlach
Torsten Haferlach MLL Munich Leukemia Laboratory
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Yuichi Shiraishi
Yuichi Shiraishi University of Tokyo
Guillermo Garcia-Manero
Guillermo Garcia-Manero The University of Texas MD Anderson Cancer Center

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