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Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
132
Citations
58574
World Ranking
177
National Ranking
112

James L. Manley publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where James L. Manley sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 355 publications — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

James L. Manley D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where James L. Manley sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 132 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2006 - Fellow of the American Academy of Arts and Sciences

Overview

James L. Manley is affiliated with Columbia University in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology.

Their work spans a variety of subfields including:

  • Molecular Biology
  • Neurology
  • Genetics
  • Hematology
  • Immunology

Manley's research topics cover multiple areas related to RNA and disease, specifically:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Amyotrophic Lateral Sclerosis Research
  • Acute Myeloid Leukemia Research
  • Neurogenetic and Muscular Disorders Research
  • RNA regulation and disease

Their recent publications include:

  • "ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs" (2020), Genes & Development
  • "SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation" (2020), Autophagy
  • "SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes" (2021), Proceedings of the National Academy of Sciences
  • "Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation" (2020), Nature Communications
  • "Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains" (2020), Genome Research

Frequent coauthors who collaborate with Manley include:

  • Zhaoqi Liu
  • Jian Zhang
  • Pedro Bak-Gordon
  • Shuang Feng
  • Lizhi Liu

The scientist frequently publishes in the following venues:

  • Genes & Development
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • RNA Biology
  • Cell Reports

Among their recognitions, James L. Manley has been named a Fellow of the American Association for the Advancement of Science (AAAS) in 2008 and a Fellow of the American Academy of Arts and Sciences in 2006.

Best Publications

  • DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract

    James L. Manley;Andrew Fire;Amparo Cano;Phillip A. Sharp

  • Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

    Mo Chen;James L. Manley

  • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

    Charles J. David;Mo Chen;Marcela Assanah;Peter Canoll

  • Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

    Yingwu Xu;Xiao Tao;Baohe Shen;Tiffany Horng

  • Mechanism and regulation of mRNA polyadenylation

    Diana F. Colgan;James L. Manley

  • Alternative polyadenylation of mRNA precursors.

    Bin Tian;James L. Manley

  • SR proteins and splicing control.

    J L Manley;R Tacke

  • Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

    Charles J. David;James L. Manley

  • Inactivation of the SR Protein Splicing Factor ASF/SF2 Results in Genomic Instability

    Xialu Li;James L. Manley

  • Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

    Jhumku D. Kohtz;Sharon F. Jamison;Cindy L. Will;Ping Zuo;Ping Zuo

  • Mechanisms and Consequences of Alternative Polyadenylation

    Dafne Campigli Di Giammartino;Kensei Nishida;James L. Manley

  • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

    Karen Colwill;Tony Pawson;Brenda Andrews;Jayendra Prasad

  • RNA polymerase II and the integration of nuclear events

    Yutaka Hirose;James L. Manley

  • The RNA polymerase II CTD coordinates transcription and RNA processing

    Jing-Ping Hsin;James L. Manley

  • A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro

    Hui Ge;James L. Manley

  • A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy.

    Tsuyoshi Kashima;James L Manley

  • Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing.

    Robert J. Sims;Scott Millhouse;Chi-Fu Chen;Brian A. Lewis

  • Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

    Yongsheng Shi;Dafne Campigli Di Giammartino;Derek Taylor;Ali Sarkeshik

  • The Polyadenylation Factor CstF-64 Regulates Alternative Processing of IgM Heavy Chain Pre-mRNA during B Cell Differentiation

    Yoshio Takagaki;Rebecca L Seipelt;Martha L Peterson;James L Manley

  • Transcriptional repression of eukaryotic promoters.

    Michael Levine;James L. Manley

Frequent Co-Authors

Carol Prives
Carol Prives Columbia University
Bin Tian
Bin Tian The Wistar Institute
Liang Tong
Liang Tong Columbia University
Michael S. Levine
Michael S. Levine Princeton University
Raul Rabadan
Raul Rabadan Columbia University
John R. Yates
John R. Yates Scripps Research Institute
Richard Jove
Richard Jove Nova Southeastern University
Adrian R. Krainer
Adrian R. Krainer Cold Spring Harbor Laboratory
Matthew Meyerson
Matthew Meyerson Harvard University

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