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Genetics

D-Index
76
Citations
20990
World Ranking
1829
National Ranking
842

Overview

Bin Tian is affiliated with The Wistar Institute in the United States. Their research primarily spans multiple interconnected fields, including Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad areas, Tian's work focuses on subfields such as Molecular Biology, Epidemiology, Immunology, Cardiology and Cardiovascular Medicine, as well as Public Health, Environmental and Occupational Health.

The main topics covered in Tian's research include:

  • Herpesvirus Infections and Treatments
  • RNA Research and Splicing
  • Mosquito-borne diseases and control
  • Viral Infections and Immunology Research
  • RNA modifications and cancer
  • Cytomegalovirus and herpesvirus research
  • Interferon and immune responses

Bin Tian has contributed to numerous publications with a strong presence in specialized journals. Frequent publication venues include:

  • Poultry Science
  • Frontiers in Microbiology
  • Veterinary Research
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Among recent papers associated with Tian's research are:

  • "U1 snRNP regulates chromatin retention of noncoding RNAs" (2020) published in Nature
  • "The role of host eIF2α in viral infection" (2020) published in Virology Journal
  • "SOCS Proteins Participate in the Regulation of Innate Immune Response Caused by Viruses" (2020) published in Frontiers in Immunology
  • "ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs" (2020) published in Genes & Development
  • "Genomic Analysis Revealed a Convergent Evolution of LINE-1 in Coat Color: A Case Study in Water Buffaloes (Bubalus bubalis)" (2020) published in Molecular Biology and Evolution

Research collaborations form an important part of Tian's scientific work. Frequent co-authors include:

  • Mafeng Liu
  • Shun Chen
  • Renyong Jia
  • Dekang Zhu
  • Juan Huang

Best Publications

  • Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart

    Ralph R. Alcendor;Shumin Gao;Peiyong Zhai;Daniela Zablocki

  • Alternative polyadenylation of mRNA precursors.

    Bin Tian;James L. Manley

  • A large-scale analysis of mRNA polyadenylation of human and mouse genes

    Bin Tian;Jun Hu;Haibo Zhang;Carol S. Lutz

  • Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

    William A. Freed-Pastor;Hideaki Mizuno;Xi Zhao;Anita Langerød

  • Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

    Zhe Ji;Ju Youn Lee;Zhenhua Pan;Bingjun Jiang

  • RNA-Seq methods for transcriptome analysis

    Radmila Hrdlickova;Masoud Toloue;Bin Tian

  • Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

    Mainul Hoque;Zhe Ji;Dinghai Zheng;Wenting Luo

  • A deletion mutation in TaHRC confers Fhb1 resistance to Fusarium head blight in wheat

    Zhenqi Su;Amy Bernardo;Bin Tian;Hui Chen

  • Biased alternative polyadenylation in human tissues

    Haibo Zhang;Ju Youn Lee;Bin Tian

  • Alternative cleavage and polyadenylation: the long and short of it

    Bin Tian;James L. Manley

  • The double-stranded-RNA-binding motif: interference and much more

    Bin Tian;Philip C. Bevilacqua;Amy Diegelman-Parente;Michael B. Mathews

  • Characterization of the mouse IFN-λ ligand-receptor system: IFN-λs exhibit antitumor activity against B16 melanoma

    Ahmed Lasfar;Anita Lewis-Antes;Sergey V Smirnov;Shubha Anantha

  • Reprogramming of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation in Generation of Pluripotent Stem Cells from Different Cell Types

    Zhe Ji;Bin Tian

  • Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation

    Jun Hu;Carol S. Lutz;Jeffrey Wilusz;Bin Tian

  • Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR.

    Bin Tian;Robert J. White;Tianbing Xia;Stephen Welle

  • Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation.

    Wencheng Li;Bei You;Mainul Hoque;Dinghai Zheng

  • Signals for pre-mRNA cleavage and polyadenylation

    Bin Tian;Joel H. Graber

  • Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing.

    Bin Tian;Zhenhua Pan;Ju Youn Lee

  • Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

    Fan Zhang;Patrick R. Romano;Tokiko Nagamura-Inoue;Bin Tian

  • Association between gene expression profile and tumor invasion in oral squamous cell carcinoma

    Gokce Altay Toruner;Gokce Altay Toruner;Gokce Altay Toruner;Celal Ulger;Celal Ulger;Celal Ulger;Mualla Alkan;Mualla Alkan;Anthony T. Galante

Frequent Co-Authors

Junichi Sadoshima
Junichi Sadoshima Rutgers, The State University of New Jersey
James L. Manley
James L. Manley Columbia University
Stephen F. Vatner
Stephen F. Vatner Rutgers, The State University of New Jersey
Harold N. Trick
Harold N. Trick Kansas State University
Dorothy E. Vatner
Dorothy E. Vatner Rutgers, The State University of New Jersey
Michael B. Mathews
Michael B. Mathews Rutgers, The State University of New Jersey
Guihua Bai
Guihua Bai United States Department of Agriculture
Lynne E. Maquat
Lynne E. Maquat University of Rochester
Jeffrey Wilusz
Jeffrey Wilusz Colorado State University
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital

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