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D-Index & Metrics

Molecular Biology

D-Index
63
Citations
12714
World Ranking
1814
National Ranking
909

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeffrey Wilusz is a researcher affiliated with Colorado State University in the United States. Their primary area of expertise lies within Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology. Their work also touches on subfields such as Plant Science, Cancer Research, Cardiology and Cardiovascular Medicine, and Infectious Diseases.

Their research topics cover a range of subjects related to RNA and cancer biology, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research
  • DNA Repair Mechanisms
  • Mitochondrial Function and Pathology
  • Cancer-related gene regulation

Jeffrey Wilusz has published several papers, notable among them are:

  • "YTHDF2 destabilizes m6A-modified neural-specific RNAs to restrain differentiation in induced pluripotent stem cells" (2020) in RNA
  • "The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention" (2020) in Wiley Interdisciplinary Reviews - RNA
  • "Aedes aegypti miRNA-33 modulates permethrin induced toxicity by regulating VGSC transcripts" (2021) in Scientific Reports
  • "Mind the Gapmer: Implications of Co-transcriptional Cleavage by Antisense Oligonucleotides" (2020) in Molecular Cell
  • "A plant-infecting subviral RNA associated with poleroviruses produces a subgenomic RNA which resists exonuclease XRN1 in vitro" (2021) in Virology

Their frequent coauthors include:

  • John R. Anderson
  • David G. Maranon
  • Gus Waneka
  • Joseph Stewart
  • Wentao Li

Jeffrey Wilusz has contributed to several publication venues, particularly in:

  • Virology
  • RNA
  • Wiley Interdisciplinary Reviews - RNA
  • Scientific Reports
  • Molecular Cell

In recognition of their contributions to science, they were named a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • The highways and byways of mRNA decay.

    Nicole L. Garneau;Jeffrey Wilusz;Carol J. Wilusz

  • Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

    Irma Sánchez-Vargas;Jaclyn C. Scott;B. Katherine Poole-Smith;Alexander W. E. Franz

  • The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.

    Devi Mukherjee;Min Gao;J.Patrick O'Connor;Reinout Raijmakers

  • Bringing the role of mRNA decay in the control of gene expression into focus.

    Carol J. Wilusz;Jeffrey Wilusz

  • C6/36 Aedes albopictus cells have a dysfunctional antiviral RNA interference response.

    Doug E. Brackney;Jaclyn C. Scott;Fumihiko Sagawa;Jimmy E. Woodward

  • The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location.

    C C MacDonald;J Wilusz;T Shenk

  • ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system

    Lance P. Ford;Janice Watson;Jack D. Keene;Jeffrey Wilusz

  • Aedes aegypti uses RNA interference in defense against Sindbis virus infection

    Corey L Campbell;Kimberly M Keene;Douglas E Brackney;Ken E Olson

  • Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation

    Jun Hu;Carol S. Lutz;Jeffrey Wilusz;Bin Tian

  • A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements

    Min Gao;Carol J. Wilusz;Stuart W. Peltz;Jeffrey Wilusz

  • Cleavage site determinants in the mammalian polyadenylation signal.

    Fan Chen;C. C. Macdonald;J. Wilusz

  • A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.

    Y Takagaki;J L Manley;C C MacDonald;J Wilusz

  • A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif.

    Jeffrey Wilusz;Thomas Eugene Shenk

  • Interaction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitro.

    Min Gao;David T. Fritz;Lance P. Ford;Jeffrey Wilusz

  • A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability.

    Stephanie L. Moon;John R. Anderson;Yutaro Kumagai;Carol J. Wilusz

  • CUG-BP binds to RNA substrates and recruits PARN deadenylase.

    Karen C.M. Moraes;Carol J. Wilusz;Jeffrey Wilusz

  • Eukaryotic Lsm proteins: lessons from bacteria

    Carol J Wilusz;Jeffrey Wilusz

  • Systematic Analysis of Cis-Elements in Unstable mRNAs Demonstrates that CUGBP1 Is a Key Regulator of mRNA Decay in Muscle Cells

    Jerome E. Lee;Ju Youn Lee;Jeffrey Wilusz;Bin Tian

  • hnRNP F Influences Binding of a 64-Kilodalton Subunit of Cleavage Stimulation Factor to mRNA Precursors in Mouse B Cells

    Kristen L. Veraldi;George K. Arhin;Kathleen Martincic;Ling-Hsiu Chung-Ganster

  • The poly(A) tail inhibits the assembly of a 3'-to-5' exonuclease in an in vitro RNA stability system.

    L P Ford;P S Bagga;J Wilusz

Frequent Co-Authors

John R. Anderson
John R. Anderson Carnegie Mellon University
Jack D. Keene
Jack D. Keene Duke University
Thomas Shenk
Thomas Shenk Princeton University
Bin Tian
Bin Tian The Wistar Institute
Ken E. Olson
Ken E. Olson Colorado State University
Carol D. Blair
Carol D. Blair Colorado State University
Gregory D. Ebel
Gregory D. Ebel Colorado State University
Joann Mudge
Joann Mudge National Center for Genome Resources
William C. Black
William C. Black Colorado State University
Robert N. Lightowlers
Robert N. Lightowlers Newcastle University

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