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Biology and Biochemistry

D-Index
59
Citations
12882
World Ranking
12502
National Ranking
889

Overview

Elmar Wahle is affiliated with Martin Luther University Halle-Wittenberg in Germany. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology as a subfield. Their scientific contributions emphasize RNA research and splicing, RNA and protein synthesis mechanisms, and RNA modifications in relation to cancer.

The scientist's work addresses several main topics, including:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Genetics, Aging, and Longevity in Model Organisms
  • Heat shock proteins research
  • Molecular Biology Techniques and Applications

Elmar Wahle's recent publications demonstrate an engagement with molecular and cellular mechanisms, particularly focusing on RNA biology. Some notable recent papers include:

  • Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition, 2020, Cell Reports
  • Reconstitution of 3' end processing of mammalian pre-mRNA reveals a central role of RBBP6, 2022, Genes & Development
  • RNA binding proteins Smaug and Cup induce CCR4-NOT-dependent deadenylation of the nanos mRNA in a reconstituted system, 2023, Nucleic Acids Research
  • RNA binding proteins Smaug and Cup induce CCR4-NOT-dependent deadenylation of the nanos mRNA in a reconstituted system, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Establishment of 5'-3' interactions in mRNA independent of a continuous ribose-phosphate backbone, 2020, RNA

The scientist has collaborated frequently with several coauthors, including:

  • Filip Pekovic
  • Christiane Rammelt
  • Christian Ihling
  • Florian Kluge
  • Uwe Kühn

Elmar Wahle's studies have been published across a range of venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Genes & Development
  • Nucleic Acids Research
  • RNA

Best Publications

  • Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

    Erwin van Dijk;Nicolas Cougot;Sylke Meyer;Sylvie Babajko

  • Messenger RNA turnover in eukaryotes: pathways and enzymes.

    Sylke Meyer;Claudia Temme;Elmar Wahle

  • The Biochemistry of 3′-End Cleavage and Polyadenylation of Messenger RNA Precursors

    Elmar Wahle;Walter Keller

  • 3′‐End processing of pre‐mRNA in eukaryotes

    Elmar Wahle;Ursula Rüegsegger

  • Structure and function of poly(A) binding proteins.

    Uwe Kühn;Elmar Wahle

  • A Novel poly(A)-binding Protein Acts as a Specificity Factor in the Second Phase of Messenger RNA Polyadenylation

    Elmar Wahle

  • Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.

    Doreen Weidensdorfer;Nadine Stöhr;Anne Baude;Marcell Lederer

  • Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA

    Angelo Calado;Fernando M.S. Tomé;Bernard Brais;G.A. Rouleau

  • Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease

    Christof G. Körner;Elmar Wahle

  • The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes

    Christof G. Körner;Michael Wormington;Martina Muckenthaler;Sandra Schneider

  • Poly(A) Tail Length Control Is Caused by Termination of Processive Synthesis

    Elmar Wahle

  • Assembly of a processive messenger RNA polyadenylation complex

    S Bienroth;W Keller;E Wahle

  • Control of poly(A) tail length

    Christian R. Eckmann;Christiane Rammelt;Elmar Wahle

  • A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila.

    Claudia Temme;Sophie Zaessinger;Sylke Meyer;Martine Simonelig

  • Poly(A) tail metabolism and function in eucaryotes.

    A Sachs;E Wahle

  • RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes

    Elmar Wahle;G. Sebastiaan Winkler

  • The biochemistry of polyadenylation

    Elmar Wahle;Walter Keller

  • Cap-dependent deadenylation of mRNA.

    Eva Dehlin;Michael Wormington;Christof G. Körner;Elmar Wahle

  • Poly(A) tail length is controlled by the nuclear poly(A) binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor

    Uwe Kühn;Miriam Gündel;Anne Knoth;Yvonne Kerwitz

  • Purification of the cleavage and polyadenylation factor involved in the 3'-processing of messenger RNA precursors.

    S Bienroth;E Wahle;C Suter-Crazzolara;W Keller

Frequent Co-Authors

Walter Keller
Walter Keller University of Basel
Andrea Sinz
Andrea Sinz Martin Luther University Halle-Wittenberg
Hauke Lilie
Hauke Lilie Martin Luther University Halle-Wittenberg
Maria Carmo-Fonseca
Maria Carmo-Fonseca University of Lisbon
Annette G. Beck-Sickinger
Annette G. Beck-Sickinger Leipzig University
Stefan Hüttelmaier
Stefan Hüttelmaier Martin Luther University Halle-Wittenberg
Alan B. Sachs
Alan B. Sachs Thermo Fisher Scientific (United States)
Gerhard Christofori
Gerhard Christofori University of Basel
Heinz Himmelbauer
Heinz Himmelbauer BOKU University
Howard D. Lipshitz
Howard D. Lipshitz University of Toronto

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