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Chemistry

D-Index
54
Citations
9706
World Ranking
12673
National Ranking
932

Overview

Andrea Sinz is affiliated with Martin Luther University Halle-Wittenberg in Germany. Their research spans several interconnected fields primarily within biochemistry, genetics, and molecular biology, alongside significant contributions in medicine. Sinz's work focuses extensively on molecular biology and spectroscopy, with involvement in infectious diseases, renewable energy, sustainability, the environment, and cancer research.

The scientist's main research topics include:

  • Mass Spectrometry Techniques and Applications
  • Advanced Proteomics Techniques and Applications
  • Advanced biosensing and bioanalysis techniques
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Acute Myeloid Leukemia Research
  • Enzyme Structure and Function

Important publication venues for Andrea Sinz have included bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Scientific Reports, and Blood.

Co-authorship collaborations have frequently involved the following researchers:

  • Christian Ihling
  • Claudio Iacobucci
  • Stefan Hüttelmaier
  • Marc Kipping
  • Panagiotis L. Kastritis

Some of the recent papers authored or co-authored by Andrea Sinz are:

  • Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein-Protein InteractionsA Method for All Seasons (2021, Chemical Reviews)
  • Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients (2020, Journal of Proteome Research)
  • Flexibility of intrinsically disordered degrons in AUX/IAA proteins reinforces auxin co-receptor assemblies (2020, Nature Communications)
  • Direct Observation of "Elongated" Conformational States in α-Synuclein upon Liquid-Liquid Phase Separation (2022, Angewandte Chemie International Edition)
  • The COVID-19 MS Coalition-accelerating diagnostics, prognostics, and treatment (2020, The Lancet)

Best Publications

  • Chemical cross-linking and mass spectrometry to map three-dimensional protein structures and protein-protein interactions.

    Andrea Sinz

  • Chemical cross-linking and mass spectrometry for mapping three-dimensional structures of proteins and protein complexes.

    Andrea Sinz

  • StavroX—A Software for Analyzing Crosslinked Products in Protein Interaction Studies

    Michael Götze;Jens Pettelkau;Sabine Schaks;Konstanze Bosse

  • Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters.

    Stefan Kalkhof;Andrea Sinz

  • Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein-Protein Interactions─A Method for All Seasons.

    Lolita Piersimoni;Panagiotis L. Kastritis;Christian Arlt;Andrea Sinz

  • Automated assignment of MS/MS cleavable cross-links in protein 3D-structure analysis.

    Michael Götze;Jens Pettelkau;Romy Fritzsche;Christian H. Ihling

  • Cleavable Cross-Linker for Protein Structure Analysis: Reliable Identification of Cross-Linking Products by Tandem MS

    Mathias Q. Müller;Frank Dreiocker;Christian H. Ihling;Mathias Schäfer

  • Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients.

    Christian Ihling;Dirk Tänzler;Sven Hagemann;Astrid Kehlen

  • A cross-linking/mass spectrometry workflow based on MS-cleavable cross-linkers and the MeroX software for studying protein structures and protein-protein interactions.

    Claudio Iacobucci;Michael Götze;Michael Götze;Christian H. Ihling;Christine Piotrowski

  • Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis.

    Andrea Sinz;Marcus Bantscheff;Stefan Mikkat;Bruno Ringel

  • Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

    Claudia Temme;Lianbing Zhang;Elisabeth Kremmer;Christian Ihling

  • Cross-Linking/Mass Spectrometry for Studying Protein Structures and Protein-Protein Interactions: Where Are We Now and Where Should We Go from Here?

    Andrea Sinz

  • Divide and conquer: cleavable cross-linkers to study protein conformation and protein-protein interactions.

    Andrea Sinz

  • A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions.

    Michael Götze;Claudio Iacobucci;Christian H. Ihling;Andrea Sinz

  • The advancement of chemical cross-linking and mass spectrometry for structural proteomics: from single proteins to protein interaction networks

    Andrea Sinz

  • Mapping the topology and determination of a low-resolution three-dimensional structure of the calmodulin-melittin complex by chemical cross-linking and high-resolution FTICRMS: direct demonstration of multiple binding modes.

    Daniela M. Schulz;Christian Ihling;G. Marius Clore;Andrea Sinz

  • Chemical cross‐linking and native mass spectrometry: A fruitful combination for structural biology

    Andrea Sinz;Christian Arlt;Dror Chorev;Michal Sharon

  • First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

    Claudio Iacobucci;Christine Piotrowski;Ruedi Aebersold;Ruedi Aebersold;Bruno C. Amaral

  • Investigation of protein–protein interactions in living cells by chemical crosslinking and mass spectrometry

    Andrea Sinz

  • Mapping low-resolution three-dimensional protein structures using chemical cross-linking and Fourier transform ion-cyclotron resonance mass spectrometry.

    Gry H. Dihazi;Andrea Sinz

Frequent Co-Authors

Ludger A. Wessjohann
Ludger A. Wessjohann Leibniz Association
Karl Mechtler
Karl Mechtler Research Institute of Molecular Pathology
Olaf Jahn
Olaf Jahn Max Planck Society
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Frank Sobott
Frank Sobott University of Leeds
Elmar Wahle
Elmar Wahle Martin Luther University Halle-Wittenberg
Annette G. Beck-Sickinger
Annette G. Beck-Sickinger Leipzig University
Stefan Hüttelmaier
Stefan Hüttelmaier Martin Luther University Halle-Wittenberg
Vichai Reutrakul
Vichai Reutrakul Mahidol University
Jens Meiler
Jens Meiler Vanderbilt University

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