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Christoph H. Borchers

Christoph H. Borchers

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Chemistry
Canada
2025

D-Index & Metrics

Chemistry

D-Index
80
Citations
25552
World Ranking
3386
National Ranking
79

Biology and Biochemistry

D-Index
88
Citations
30253
World Ranking
2688
National Ranking
82

Research.com Recognitions

  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award

Overview

Christoph H. Borchers is affiliated with McGill University in Canada, contributing extensively to the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research output includes a significant focus on molecular biology and spectroscopy, along with specialized work in oncology, cancer research, and pulmonary and respiratory medicine.

The main topics covered in their research encompass advanced proteomics techniques and applications, mass spectrometry techniques and applications, and metabolomics combined with mass spectrometry studies. Other important topics in their portfolio include cancer, hypoxia, and metabolism; enzyme structure and function; metabolism related to diabetes and cancer; and mechanisms of neuroinflammation and neurodegeneration.

Frequent collaborators in their work include René P. Zahedi, Vincent R. Richard, Yassene Mohammed, Evgeniy V. Petrotchenko, and Andrew J. Link.

They have published extensively in multiple venues, with the highest number of publications appearing in PROTEOMICS, UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Journal of Proteome Research, and Molecular & Cellular Proteomics.

Recent papers highlight a range of topics and venues:

  • Mass-Spectrometric Detection of SARS-CoV-2 Virus in Scrapings of the Epithelium of the Nasopharynx of Infected Patients via Nucleocapsid N Protein, 2020, Journal of Proteome Research
  • Profiling of Metabolites of Bacillus spp. and Their Application in Sustainable Plant Growth Promotion and Biocontrol, 2021, Frontiers in Sustainable Food Systems
  • Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation, 2023, Cell Metabolism
  • Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID, 2023, Cell Reports Medicine
  • Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry, 2020, Structure

Best Publications

  • Histone demethylation by a family of JmjC domain-containing proteins

    Yu Ichi Tsukada;Jia Fang;Jia Fang;Hediye Erdjument-Bromage;Maria E. Warren

  • Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

    Terri A. Addona;Susan E. Abbatiello;Birgit Schilling;Steven J. Skates

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Purification and Functional Characterization of a Histone H3-Lysine 4-Specific Methyltransferase

    Hengbin Wang;Ru Cao;Li Xia;Hediye Erdjument-Bromage

  • Multiple Reaction Monitoring-based, Multiplexed, Absolute Quantitation of 45 Proteins in Human Plasma

    Michael A. Kuzyk;Derek Smith;Juncong Yang;Tyra J. Cross

  • JNK phosphorylates paxillin and regulates cell migration

    Cai Huang;Zenon Rajfur;Christoph Borchers;Michael D. Schaller

  • Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

    Steven A. Carr;Susan E. Abbatiello;Bradley L. Ackermann;Christoph Borchers

  • Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.

    Manabu Furukawa;Yizhou Joseph He;Christoph Borchers;Yue Xiong

  • Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast

    Tiaojiang Xiao;Hana Hall;Kelby O. Kizer;Yoichiro Shibata

  • An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography-tandem mass spectrometry.

    Jun Han;Karen Lin;Carita Sequeira;Christoph H. Borchers

  • The human proteome project: Current state and future direction

    Pierre Legrain;Ruedi Aebersold;Ruedi Aebersold;Alexander Archakov;Amos Marc Bairoch

  • A HUPO test sample study reveals common problems in mass spectrometry–based proteomics

    Alexander W. Bell;Eric W. Deutsch;Catherine E. Au;Robert E. Kearney

  • Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

    John A. Bowden;Alan Heckert;Candice Z. Ulmer;Christina M. Jones

  • Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

    Tobias Eckle;Katherine Hartmann;Stephanie Bonney;Susan Reithel

  • Current trends in quantitative proteomics

    Monica H. Elliott;Derek S. Smith;Carol E. Parker;Christoph Borchers

  • Architecture of the RNA polymerase II–Mediator core initiation complex.

    C. Plaschka;L. Larivière;L. Wenzeck;M. Seizl

  • A Quantitative Study of the Effects of Chaotropic Agents, Surfactants, and Solvents on the Digestion Efficiency of Human Plasma Proteins by Trypsin

    Jennifer L. Proc;Michael A. Kuzyk;Darryl B. Hardie;Juncong Yang

  • Mass Spectrometric Characterization of the Glycosylation Pattern of HIV-gp120 Expressed in CHO Cells

    Xuegong Zhu;Christoph Borchers;Rachelle J. Bienstock;Kenneth B. Tomer

  • Effect of Antibiotic Treatment on the Intestinal Metabolome

    L. Caetano M. Antunes;Jun Han;Rosana B. R. Ferreira;Petra Lolić

  • Mass spectrometry based biomarker discovery, verification, and validation--quality assurance and control of protein biomarker assays.

    Carol E. Parker;Christoph H. Borchers

Frequent Co-Authors

Carol E. Parker
Carol E. Parker National Institute of Environmental Health Sciences
Ahmed El-Sohemy
Ahmed El-Sohemy University of Toronto
B. Brett Finlay
B. Brett Finlay University of British Columbia
Kenneth B. Tomer
Kenneth B. Tomer National Institutes of Health
Steven A. Carr
Steven A. Carr Broad Institute
Eric W. Deutsch
Eric W. Deutsch University of Washington
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
daniel c liebler
daniel c liebler Vanderbilt University
Robert L. Moritz
Robert L. Moritz Institute for Systems Biology
Bruce M. McManus
Bruce M. McManus University of British Columbia

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