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D-Index & Metrics

Molecular Biology

D-Index
76
Citations
23693
World Ranking
1144
National Ranking
593

Overview

William F. Marzluff is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research centers predominantly in the fields of Biochemistry, Genetics, and Molecular Biology, with a primary focus on Molecular Biology. Other subfields of study include Plant Science, Cancer Research, Cardiology and Cardiovascular Medicine, and Genetics.

The scientist's work covers several interconnected topics in molecular and cellular biology. These include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation

Marzluff has published extensively, with contributions spread across various scientific journals and repositories. Frequent publication venues include:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Biology of the Cell
  • RNA
  • Nature Communications

Recent significant papers authored or co-authored by Marzluff include:

  • "Structure of an active human histone pre-mRNA 3'-end processing machinery" (2020) published in Science
  • "CDK-Regulated Phase Separation Seeded by Histone Genes Ensures Precise Growth and Function of Histone Locus Bodies" (2020) published in Developmental Cell
  • "Engineering highly efficient backsplicing and translation of synthetic circRNAs" (2021) published in Molecular Therapy - Nucleic Acids
  • "A standardized nomenclature for mammalian histone genes" (2022) published in Epigenetics & Chromatin
  • "CRL4 DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development" (2020) published in Science Advances

The collaborative nature of their research is evident from frequent co-authors, including:

  • Zbigniew Domiński
  • Robert J. Duronio
  • Rita M. Meganck
  • Joshua D. Welch
  • Liang Tong

This extensive network of research topics, publication outlets, and collaborative partnerships underscores a focus on understanding molecular mechanisms in RNA biology, chromatin dynamics, and related cellular processes relevant to genetics and disease investigation.

Best Publications

  • Circular RNAs are abundant, conserved, and associated with ALU repeats

    William R. Jeck;Jessica A. Sorrentino;Kai Wang;Michael K. Slevin

  • The genome of the sea urchin Strongylocentrotus purpuratus.

    Erica Sodergren;George M. Weinstock;Eric H. Davidson;R. Andrew Cameron

  • Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

    William F. Marzluff;Eric J. Wagner;Robert J. Duronio

  • The human and mouse replication-dependent histone genes.

    William F. Marzluff;Preetam Gongidi;Keith R. Woods;Jianping Jin

  • Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5′ to 3′ and 3′ to 5′

    Thomas E. Mullen;William F. Marzluff

  • A unified phylogeny-based nomenclature for histone variants

    Paul B Talbert;Kami Ahmad;Geneviève Almouzni;Juan Ausió

  • Formation of the 3' end of histone mRNA.

    Zbigniew Dominski;William F Marzluff

  • Histone mRNA concentrations are regulated at the level of transcription and mRNA degradation

    Donald B. Sittman;Reed A. Graves;William F. Marzluff

  • Histone mRNA expression: multiple levels of cell cycle regulation and important developmental consequences.

    William F Marzluff;Robert J Duronio

  • The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.

    Zeng Feng Wang;Michael L. Whitfield;Thomas C. Ingledue;Zbigniew Dominski

  • Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms.

    Michael L. Whitfield;Lian Xing Zheng;Amy Baldwin;Tomohiko Ohta

  • Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps.

    Michael E. Harris;Ruth Böhni;Martin H. Schneiderman;Lakshman Ramamurthy

  • The Polyadenylation Factor CPSF-73 Is Involved in Histone-Pre-mRNA Processing

    Zbigniew Dominski;Xiao Cui Yang;William F. Marzluff

  • Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

    Handan Kaygun;William F Marzluff

  • Regulation of histone mRNA production and stability in serum-stimulated mouse 3T6 fibroblasts

    A. J. DeLisle;R. A. Graves;William F Marzluff;L. F. Johnson

  • Formation of the 3' end of histone mRNA: getting closer to the end.

    Zbigniew Dominski;William F. Marzluff

  • Birth and Death of Histone mRNAs.

    William F. Marzluff;Kaitlin P. Koreski

  • Cell cycle regulation of mouse H3 histone mRNA metabolism.

    R. B. Alterman;S. Ganguly;D. H. Schulze;William F Marzluff

  • Stem-Loop Binding Protein Facilitates 3′-End Formation by Stabilizing U7 snRNP Binding to Histone Pre-mRNA

    Zbigniew Dominski;Lian Xing Zheng;Ricardo Sanchez;William F. Marzluff

  • Metazoan replication-dependent histone mRNAs: a distinct set of RNA polymerase II transcripts

    William F Marzluff

Frequent Co-Authors

Robert J. Duronio
Robert J. Duronio University of North Carolina at Chapel Hill
Michal Dadlez
Michal Dadlez Polish Academy of Sciences
Michael L. Whitfield
Michael L. Whitfield Dartmouth College
Liang Tong
Liang Tong Columbia University
Christoph H. Borchers
Christoph H. Borchers McGill University
Gary M. Wessel
Gary M. Wessel Brown University
Aravind Asokan
Aravind Asokan Duke University
Arthur I. Skoultchi
Arthur I. Skoultchi Albert Einstein College of Medicine
Christine G. Elsik
Christine G. Elsik University of Missouri
Arcady Mushegian
Arcady Mushegian National Science Foundation

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