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Andrzej Dziembowski

Andrzej Dziembowski

D-Index & Metrics

Molecular Biology

D-Index
51
Citations
10039
World Ranking
2502
National Ranking
1237

Research.com Recognitions

  • 2020 - Polish Academy of Science
  • 2018 - Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej for explaining the function of key enzymes involved in RNA degradation, the dysfunction of which leads to pathological states
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Andrzej Dziembowski is affiliated with United Way in the United States and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a specialized focus on Molecular Biology. Their research spans related subfields including Genetics, Cancer Research, Aging, and Immunology.

The scientist's main research topics include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA Interference and Gene Delivery
  • Genetics, Aging, and Longevity in Model Organisms
  • Connective tissue disorders research
  • MicroRNA in disease regulation

Dziembowski has published numerous papers in well-recognized venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • RNA
  • Wiley Interdisciplinary Reviews - RNA

Selected recent papers include:

  • "Mitochondrial protein biogenesis in the synapse is supported by local translation," 2020, EMBO Reports
  • "Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C," 2020, Nature Communications
  • "Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae," 2021, Nature Communications
  • "Measuring the tail: Methods for poly(A) tail profiling," 2022, Wiley Interdisciplinary Reviews - RNA
  • "The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis," 2021, Nature Communications

Frequent co-authors who have collaborated significantly with Dziembowski include:

  • Seweryn Mroczek
  • Paweł S. Krawczyk
  • Olga Gewartowska
  • Jakub Gruchota
  • Natalia Gumińska

Throughout their career, Andrzej Dziembowski has received recognition in the form of several awards:

  • Polish Academy of Science, 2020
  • Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej, 2018, for explaining the function of key enzymes involved in RNA degradation, the dysfunction of which leads to pathological states
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Mitochondrial double-stranded RNA triggers antiviral signalling in humans

    Ashish Dhir;Somdutta Dhir;Lukasz S. Borowski;Lukasz S. Borowski;Laura Jimenez

  • A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

    Andrzej Dziembowski;Esben Lorentzen;Elena Conti;Bertrand Séraphin

  • PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures.

    Pawel S Krawczyk;Leszek Lipinski;Andrzej Dziembowski;Andrzej Dziembowski

  • Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

    Michal Szymon Lubas;Marianne Spangsberg Christensen;Maiken Søndergaard Kristiansen;Michal Domanski

  • Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

    Lidia Wrobel;Ulrike Topf;Piotr Bragoszewski;Sebastian Wiese;Sebastian Wiese

  • Endonucleolytic RNA cleavage by a eukaryotic exosome

    Alice Lebreton;Alice Lebreton;Rafal Tomecki;Rafal Tomecki;Andrzej Dziembowski;Andrzej Dziembowski;Bertrand Séraphin;Bertrand Séraphin

  • Structural and Biochemical Insights to the Role of the Ccr4-not Complex and Ddx6 ATPase in Microrna Repression.

    Hansruedi Mathys;Hansruedi Mathys;Jérôme Basquin;Sevim Ozgur;Mariusz Czarnocki-Cieciura;Mariusz Czarnocki-Cieciura;Mariusz Czarnocki-Cieciura

  • The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

    Rafal Tomecki;Rafal Tomecki;Maiken Søndergaard Kristiansen;Søren Lykke-Andersen;Aleksander Chlebowski

  • RNA decay machines: the exosome.

    Aleksander Chlebowski;Michał Lubas;Michał Lubas;Michał Lubas;Torben Heick Jensen;Andrzej Dziembowski;Andrzej Dziembowski

  • Cytoplasmic RNA decay pathways - enzymes and mechanisms.

    Anna Łabno;Rafał Tomecki;Rafał Tomecki;Andrzej Dziembowski;Andrzej Dziembowski

  • Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci

    Lukasz S. Borowski;Andrzej Dziembowski;Monika S. Hejnowicz;Piotr P. Stepien

  • Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the RNase II Nuclease Family

    Esben Lorentzen;Jerome Basquin;Rafal Tomecki;Andrzej Dziembowski

  • Identification of a novel human nuclear-encoded mitochondrial poly(A) polymerase

    Rafal Tomecki;Aleksandra Dmochowska;Kamil Gewartowski;Andrzej Dziembowski

  • Subunit architecture of multimeric complexes isolated directly from cells

    Helena Hernández;Andrzej Dziembowski;Thomas Taverner;Bertrand Séraphin

  • The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis

    Michal Lubas;Michal Lubas;Michal Lubas;Peter Refsing Andersen;Aleks Schein;Andrzej Dziembowski;Andrzej Dziembowski

  • Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing

    Andrzej Dziembowski;Ana-Paula Ventura;Berthold Rutz;Friederike Caspary

  • The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism.

    Andrzej Dziembowski;Jan Piwowarski;Rafal Hoser;Michal Minczuk

  • Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

    Michal Lubas;Christian K Damgaard;Rafal Tomecki;Rafal Tomecki;Dominik Cysewski;Dominik Cysewski

  • Recent developments in the analysis of protein complexes1

    Andrzej Dziembowski;Bertrand Séraphin

  • The eukaryotic RNA exosome: same scaffold but variable catalytic subunits.

    Søren Lykke-Andersen;Rafal Tomecki;Torben Heick Jensen;Andrzej Dziembowski

Frequent Co-Authors

Bertrand Séraphin
Bertrand Séraphin Institute of Genetics and Molecular and Cellular Biology
Elena Conti
Elena Conti Max Planck Society
Torben Heick Jensen
Torben Heick Jensen Aarhus University
Michal Minczuk
Michal Minczuk University of Cambridge
Krzysztof Ginalski
Krzysztof Ginalski University of Warsaw
Padraic G. Fallon
Padraic G. Fallon Trinity College Dublin
José M. Valpuesta
José M. Valpuesta Spanish National Research Council
Agnieszka Chacinska
Agnieszka Chacinska IMol Polish Academy of Sciences
David Chandler
David Chandler University of California, Berkeley
Yanick J. Crow
Yanick J. Crow Université Paris Cité

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