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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Molecular Biology

D-Index
122
Citations
46896
World Ranking
244
National Ranking
16

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2004 - Fellow of the Royal Society of Edinburgh
  • 2004 - Fellow of the Royal Society, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

David Tollervey is affiliated with the University of Edinburgh in the United Kingdom. Their research primarily falls within the broad field of Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Molecular Biology. The scientist's work also extends into Cancer Research, Infectious Diseases, Genetics, and Cell Biology.

Their research topics focus on various aspects of RNA biology, including:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Fungal and yeast genetics research
  • Cancer-related molecular mechanisms research
  • Genomics and Chromatin Dynamics
  • RNA regulation and disease

David Tollervey has published extensively in several scientific venues. The most frequent venues for their publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Molecular Cell
  • SSRN Electronic Journal

Their recent notable publications include:

  • "Regulation of the RNAPII Pool Is Integral to the DNA Damage Response" (2020, Cell)
  • "Stress-Induced Translation Inhibition through Rapid Displacement of Scanning Initiation Factors" (2020, Molecular Cell)
  • "Nascent Transcript Folding Plays a Major Role in Determining RNA Polymerase Elongation Rates" (2020, Molecular Cell)
  • "A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis" (2022, Nature Communications)
  • "The promises and pitfalls of specialized ribosomes" (2022, Molecular Cell)

Throughout their career, David Tollervey has collaborated frequently with several researchers, including:

  • Tomasz W. Turowski
  • Christos Spanos
  • Vadim Shchepachev
  • Stefan Bresson
  • Aleksandra Helwak

David Tollervey's contributions to science have been recognized by several professional honors. They were named a Fellow of the Royal Society of Edinburgh and a Fellow of the Royal Society, United Kingdom, both in 2004. Additionally, they are a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Coding-sequence determinants of gene expression in Escherichia coli.

    Grzegorz Kudla;Andrew W. Murray;David Tollervey;Joshua B. Plotkin

  • Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding

    Aleksandra Helwak;Grzegorz Kudla;Tatiana Dudnakova;David Tollervey

  • The Many Pathways of RNA Degradation

    Jonathan Houseley;David Tollervey

  • The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases

    Philip Mitchell;Elisabeth Petfalski;Andrej Shevchenko;Matthias Mann

  • RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

    John LaCava;Jonathan Houseley;Cosmin Saveanu;Elisabeth Petfalski

  • Ribosome synthesis in Saccharomyces cerevisiae.

    Jaap Venema;David Tollervey

  • RNA-quality control by the exosome.

    Jonathan Houseley;John LaCava;David Tollervey

  • Functions of the exosome in rRNA, snoRNA and snRNA synthesis.

    Christine Allmang;Joanna Kufel;Guillaume Chanfreau;Guillaume Chanfreau;Philip Mitchell

  • Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation, and ribosome assembly.

    David Tollervey;Hanna Lehtonen;Ralf Jansen;Hildegard Kern

  • A new system for naming ribosomal proteins

    Nenad Ban;Roland Beckmann;Jamie H D Cate;Jonathan D Dinman

  • The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.

    Christine Allmang;Elisabeth Petfalski;Alexandre Podtelejnikov;Matthias Mann

  • Function and synthesis of small nucleolar RNAs

    David Tollervey;Tamás Kiss

  • 90S Pre-Ribosomes Include the 35S Pre-rRNA, the U3 snoRNP, and 40S Subunit Processing Factors but Predominantly Lack 60S Synthesis Factors

    Paola Grandi;Vladimir Rybin;Jochen Baßler;Elisabeth Petfalski

  • Identification of a Regulated Pathway for Nuclear Pre-mRNA Turnover

    Cécile Bousquet-Antonelli;Carlo Presutti;David Tollervey

  • Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

    Aziz El Hage;Sarah L. French;Ann L. Beyer;David Tollervey

  • 60S pre‐ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm

    Tracy A Nissan;Jochen Bassler;Elisabeth Petfalski;David Tollervey

  • The box H+ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase

    Denis L.J. Lafontaine;Cécile Bousquet-Antonelli;Yves Henry;Michèle Caizergues-Ferrer

  • Dob1p (Mtr4p) is a putative ATP‐dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae

    Jesús de la Cruz;Dieter Kressler;David Tollervey;Patrick Linder

  • The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site.

    Y. Henry;H. Wood;J.P. Morrissey;E. Petfalski

  • The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast.

    D. Tollervey;H. Lehtonen;M. Carmo-Fonseca;E. C. Hurt

Frequent Co-Authors

Sander Granneman
Sander Granneman University of Edinburgh
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Ed Hurt
Ed Hurt Heidelberg University
Denis L. J. Lafontaine
Denis L. J. Lafontaine Université Libre de Bruxelles
Jean D. Beggs
Jean D. Beggs University of Edinburgh
David L. Gally
David L. Gally University of Edinburgh
John P. Morrissey
John P. Morrissey University College Cork
Markus T. Bohnsack
Markus T. Bohnsack University of Göttingen
Maria Carmo-Fonseca
Maria Carmo-Fonseca University of Lisbon
Thomas Dandekar
Thomas Dandekar University of Würzburg

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