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Torben Heick Jensen

Torben Heick Jensen

D-Index & Metrics

Molecular Biology

D-Index
64
Citations
18271
World Ranking
1722
National Ranking
12

Overview

Torben Heick Jensen is affiliated with Aarhus University in Denmark and specializes in biochemistry, genetics, and molecular biology. Their research focuses on molecular biology, with significant work related to RNA research and splicing, RNA modifications and cancer, as well as RNA and protein synthesis mechanisms.

They have contributed extensively to several areas of RNA biology, including RNA regulation and disease, genomics and chromatin dynamics, and cancer-related molecular mechanisms and gene regulation.

Key recent publications include:

  • Integrator is a genome-wide attenuator of non-productive transcription (2020, Molecular Cell)
  • Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression (2022, Molecular Cell)
  • A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome (2020, Cell Reports)
  • circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation (2020, eLife)
  • Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae (2021, Nature Communications)

The most frequent co-authors collaborating with Torben Heick Jensen include:

  • Manfred Schmid
  • William Garland
  • Jérôme O. Rouvière
  • Guifen Wu
  • Søren Lykke-Andersen

Their work has appeared predominantly in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nucleic Acids Research
  • Cell Reports
  • Nature Communications

Best Publications

  • An atlas of active enhancers across human cell types and tissues

    Robin Andersson;Claudia Gebhard;Irene Miguel-Escalada;Ilka Hoof

  • Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.

    Søren Lykke-Andersen;Torben Heick Jensen

  • RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters

    Pascal Preker;Jesper Nielsen;Susanne Kammler;Søren Lykke-Andersen

  • Quality control of mRNA 3′-end processing is linked to the nuclear exosome

    Patricia Hilleren;Terri McCarthy;Michael Rosbash;Roy Parker

  • SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

    Andrea B Eberle;Søren Lykke-Andersen;Oliver Mühlemann;Torben Heick Jensen

  • A nucleoporin is required for induction of Ca2+ spiking in legume nodule development and essential for rhizobial and fungal symbiosis.

    Norihito Kanamori;Lene Heegaard Madsen;Simona Radutoiu;Mirela Frantescu

  • Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

    Michal Szymon Lubas;Marianne Spangsberg Christensen;Maiken Søndergaard Kristiansen;Michal Domanski

  • The exosome: a multipurpose RNA-decay machine.

    Manfred Schmid;Torben Heick Jensen

  • Interactions between mRNA Export Commitment, 3′-End Quality Control, and Nuclear Degradation

    Domenico Libri;Ken Dower;Jocelyne Boulay;Rune Thomsen

  • The Specificity of the CRM1-Rev Nuclear Export Signal Interaction Is Mediated by RanGTP*

    Peter Askjaer;Torben Heick Jensen;Jakob Nilsson;Ludwig Englmeier

  • Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality

    Evgenia Ntini;Aino I Järvelin;Jette Bornholdt;Yun Chen

  • Dealing with Pervasive Transcription

    Torben Heick Jensen;Alain Jacquier;Domenico Libri

  • The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

    Rafal Tomecki;Rafal Tomecki;Maiken Søndergaard Kristiansen;Søren Lykke-Andersen;Aleksander Chlebowski

  • RNA decay machines: the exosome.

    Aleksander Chlebowski;Michał Lubas;Michał Lubas;Michał Lubas;Torben Heick Jensen;Andrzej Dziembowski;Andrzej Dziembowski

  • A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription.

    Torben Heick Jensen;Kimberly Patricio;Terri McCarthy;Michael Rosbash

  • Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.

    Nicola Meola;Michal Domanski;Evdoxia Karadoulama;Yun Chen

  • Crosstalk between mRNA 3′ End Processing and Transcription Initiation

    Christophe K. Mapendano;Søren Lykke-Andersen;Jørgen Kjems;Edouard Bertrand

  • The human cap-binding complex is functionally connected to the nuclear RNA exosome

    Peter Refsing Andersen;Michal Domanski;Michal Domanski;Maiken Søndergaard Kristiansen;Maiken Søndergaard Kristiansen;Helena Storvall

  • The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis

    Michal Lubas;Michal Lubas;Michal Lubas;Peter Refsing Andersen;Aleks Schein;Andrzej Dziembowski;Andrzej Dziembowski

  • The DECD box Putative ATPase Sub2p Is an Early mRNA Export Factor

    Torben Heick Jensen;Jocelyne Boulay;Michael Rosbash;Domenico Libri

Frequent Co-Authors

Albin Sandelin
Albin Sandelin University of Copenhagen
Michael Rosbash
Michael Rosbash Brandeis University
Jørgen Kjems
Jørgen Kjems Aarhus University
Jens S. Andersen
Jens S. Andersen University of Southern Denmark
Edouard Bertrand
Edouard Bertrand Centre national de la recherche scientifique, CNRS
Lars M. Steinmetz
Lars M. Steinmetz Stanford University
Michael P. Rout
Michael P. Rout Rockefeller University
Claire Moore
Claire Moore Tufts University
Brian T. Chait
Brian T. Chait Rockefeller University

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