2026 Nick J. Proudfoot: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	100	752	708	108	103	212	37165
Molecular Biology	100	530	474	41	36	212	37165

Research.com Recognitions

2024 - Research.com Genetics in United Kingdom Leader Award
2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
2023 - Research.com Genetics in United Kingdom Leader Award

Overview

Nick J. Proudfoot is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple disciplines, primarily focusing on the intersection of mathematics and molecular biology.

The scientist's main fields of study include Mathematics and Biochemistry, Genetics and Molecular Biology, with extensive work also bridging Molecular Biology, Geometry and Topology, Discrete Mathematics and Combinatorics, Algebra and Number Theory, and Mathematical Physics.

Their research addresses various topics, including:

Advanced Combinatorial Mathematics
Algebraic structures and combinatorial models
RNA Research and Splicing
RNA modifications and cancer
Algebraic Geometry and Number Theory
Advanced Topics in Algebra
Genomics and Chromatin Dynamics

Nick J. Proudfoot has contributed to a number of research papers, among them recent publications:

"Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics" (2022) in Nature Reviews Molecular Cell Biology
"POINT technology illuminates the processing of polymerase-associated intact nascent transcripts" (2021) in Molecular Cell
"Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy" (2022) in Cell
"Enhancers predominantly regulate gene expression during differentiation via transcription initiation" (2021) in Molecular Cell
"A semi-small decomposition of the Chow ring of a matroid" (2022) in Advances in Mathematics

The scientist frequently collaborates with the following co-authors:

Takayuki Nojima
Rui Sousa-Luís
Gwendal Dujardin
Jacob P. Matherne
Eric Ramos

Their publications have appeared in several academic venues, including:

arXiv (Cornell University)
bioRxiv (Cold Spring Harbor Laboratory)
Advances in Mathematics
Nature Reviews Molecular Cell Biology
Molecular Cell

Best Publications

3′ Non-coding region sequences in eukaryotic messenger RNA

N. J. Proudfoot;G. G. Brownlee

3336
Citations
The structure and evolution of the human β-globin gene family

Argiris Efstratiadis;James W. Posakony;Tom Maniatis;Richard M. Lawn

1642
Citations
Integrating mRNA Processing with Transcription

Nick J. Proudfoot;Andre Furger;Michael J. Dye

1458
Citations
Pre-mRNA processing reaches back to transcription and ahead to translation.

Melissa J. Moore;Nick J. Proudfoot

1039
Citations
Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination

Konstantina Skourti-Stathaki;Nicholas J. Proudfoot;Natalia Gromak

813
Citations
Ending the message: poly(A) signals then and now

Nick J. Proudfoot

734
Citations
Human 5′ → 3′ exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

Steven West;Natalia Gromak;Nick J. Proudfoot

608
Citations
Mitochondrial double-stranded RNA triggers antiviral signalling in humans

Ashish Dhir;Somdutta Dhir;Lukasz S. Borowski;Lukasz S. Borowski;Laura Jimenez

597
Citations
Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing

Takayuki Nojima;Tomás Gomes;Ana Rita Fialho Grosso;Hiroshi Kimura

571
Citations
Poly(A) signals.

Nick Proudfoot

553
Citations
A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression

Konstantina Skourti-Stathaki;Nicholas J. Proudfoot

551
Citations
Primary microRNA transcripts are processed co-transcriptionally.

Mariangela Morlando;Monica Ballarino;Natalia Gromak;Francesca Pagano

505
Citations
Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut

Nick J. Proudfoot

500
Citations
Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

Celia J. Webby;Alexander Wolf;Natalia Gromak;Mathias Dreger

469
Citations
BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair

Elodie Hatchi;Konstantina Skourti-Stathaki;Steffen Ventz;Luca Pinello

465
Citations
Alpha-thalassaemia caused by a polyadenylation signal mutation.

D. R. Higgs;S. E. Y. Goodbourn;J. Lamb;J. B. Clegg

453
Citations
Gene loops juxtapose promoters and terminators in yeast.

Justin M O'Sullivan;Sue Mei Tan-Wong;Antonin Morillon;Barbara Lee

430
Citations
Transcriptional interference and termination between duplicated α -globin gene constructs suggests a novel mechanism for gene regulation

N. J. Proudfoot

422
Citations
A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

Richard Treisman;Nicholas J. Proudfoot;Monica Shander;Tom Maniatis

419
Citations
Intergenic transcription and transinduction of the human beta-globin locus.

Hilary L. Ashe;Joan Monks;Mark Wijgerde;Peter Fraser

417
Citations

Frequent Co-Authors

Maria Carmo-Fonseca University of Lisbon

Tom Maniatis Columbia University

Mauro Giacca King's College London

George G. Brownlee University of Oxford

Hiroshi Kimura Tokyo Institute of Technology

Melissa A. Brown University of Queensland

Manolis Kellis MIT

Douglas R. Higgs University of Oxford

Yanick J. Crow Université Paris Cité

David J. Weatherall University of Oxford

External Links

Personal website of Nick J. Proudfoot

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