World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
98
Citations
85465
World Ranking
790
National Ranking
397

Molecular Biology

D-Index
98
Citations
85465
World Ranking
560
National Ranking
307

Research.com Recognitions

  • 1990 - Fellow of the American Statistical Association (ASA)

Overview

David Bentley is affiliated with the University of Colorado Denver in the United States and specializes in biochemistry, genetics, and molecular biology. Their research focuses predominantly on molecular biology, with significant work in RNA research and splicing, RNA modifications and cancer, and mechanisms of RNA and protein synthesis. They have also contributed to genomics and chromatin dynamics, interferon and immune responses, signaling pathways in disease, and plant and fungal interactions research.

They have an extensive publication record with 67 publications in their main field of study. Their research appears frequently in several notable venues, including bioRxiv (Cold Spring Harbor Laboratory) with 6 papers, SSRN Electronic Journal with 4 papers, Molecular Cell and eLife with 3 papers each, and Genes & Development with 2 publications.

Their recent papers include:

  • Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing, published in 2021 in Molecular Cell
  • Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription, published in 2020 in Genes & Development
  • The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model, published in 2022 in Molecular Cell
  • Pre-mRNA splicing and its cotranscriptional connections, published in 2023 in Trends in Genetics
  • Xrn2 substrate mapping identifies torpedo loading sites and extensive premature termination of RNA pol II transcription, published in 2022 in Genes & Development

David Bentley has collaborated frequently with several coauthors, reflecting ongoing research partnerships in their field. Some of the most frequent coauthors include:

  • Nova Fong
  • Benjamin Erickson
  • Ryan M. Sheridan
  • Robin D. Dowell
  • Dylan J. Taatjes

Their work spans a variety of specialized topics such as RNA research and splicing with 36 publications, RNA modifications and cancer with 30 publications, and RNA and protein synthesis mechanisms with 20 publications. Other areas covered include genomics and chromatin dynamics, interferon and immune responses, as well as signaling pathways in disease and plant and fungal interactions.

In recognition of their contributions to the field, David Bentley was awarded the title of Fellow of the American Statistical Association in 1990.

Best Publications

  • Initial sequencing and analysis of the human genome.

    Eric S. Lander;Lauren M. Linton;Bruce Birren;Chad Nusbaum

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

    Sarah-Jane Dawson;Dana W Y Tsui;Muhammed Murtaza;Heather Biggs

  • Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

    Muhammed Murtaza;Sarah-Jane Dawson;Dana W. Y. Tsui;Davina Gale

  • The DNA sequence of human chromosome 22

    I. Dunham;N. Shimizu;B. A. Roe;S. Chissoe

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

    Tim Forshew;Muhammed Murtaza;Christine Parkinson;Christine Parkinson;Davina Gale

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • A gene map of the human genome

    G. D. Schuler;M. S. Boguski;E. A. Stewart;L. D. Stein

  • The C-terminal domain of RNA polymerase II couples mRNA processing to transcription.

    Susan McCracken;Nova Fong;Krassimir Yankulov;Scott Ballantyne

  • Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana

    K. Mayer;C. Schüller;R. Wambutt;G. Murphy

  • Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

    Claire Palles;Jean-Baptiste Cazier;Kimberley M Howarth;Enric Domingo

  • Coupling mRNA processing with transcription in time and space

    David L. Bentley

  • A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells.

    David L. Bentley;Mark Groudine

  • A Slow RNA Polymerase II Affects Alternative Splicing In Vivo

    Manuel de la Mata;Claudio R Alonso;Sebastián Kadener;Juan P Fededa

  • Highly parallel SNP genotyping.

    J B Fan;A Oliphant;R Shen;B G Kermani

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

    Susan McCracken;Nova Fong;Emanuel Rosonina;Krassimir Yankulov

  • Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors.

    David L Bentley

  • Common VKORC1 and GGCX polymorphisms associated with warfarin dose.

    Mia Wadelius;L.Y. Chen;K. Downes;J. Ghori

Frequent Co-Authors

Sean Humphray
Sean Humphray Illumina (United States)
Jenny C. Taylor
Jenny C. Taylor University of Oxford
Panos Deloukas
Panos Deloukas Queen Mary University of London
Terence H. Rabbitts
Terence H. Rabbitts Institute of Cancer Research
Sarah Hunt
Sarah Hunt European Bioinformatics Institute
Peter Donnelly
Peter Donnelly University of Oxford
Anna Schuh
Anna Schuh University of Oxford
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Samantha J.L. Knight
Samantha J.L. Knight University of Oxford
Nicholas A. Watkins
Nicholas A. Watkins NHS Blood and Transplant

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